BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 11598120)

  • 1. Multiple activation loop conformations and their regulatory properties in the insulin receptor's kinase domain.
    Ablooglu AJ; Frankel M; Rusinova E; Ross JB; Kohanski RA
    J Biol Chem; 2001 Dec; 276(50):46933-40. PubMed ID: 11598120
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intrasteric inhibition of ATP binding is not required to prevent unregulated autophosphorylation or signaling by the insulin receptor.
    Frankel M; Ablooglu AJ; Leone JW; Rusinova E; Ross JB; Heinrikson RL; Kohanski RA
    Mol Cell Biol; 2001 Jul; 21(13):4197-207. PubMed ID: 11390649
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism.
    Till JH; Ablooglu AJ; Frankel M; Bishop SM; Kohanski RA; Hubbard SR
    J Biol Chem; 2001 Mar; 276(13):10049-55. PubMed ID: 11124964
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Partial activation of the insulin receptor kinase domain by juxtamembrane autophosphorylation.
    Cann AD; Bishop SM; Ablooglu AJ; Kohanski RA
    Biochemistry; 1998 Aug; 37(32):11289-300. PubMed ID: 9698376
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Conformational changes in the activation loop of the insulin receptor's kinase domain.
    Frankel M; Bishop SM; Ablooglu AJ; Han YP; Kohanski RA
    Protein Sci; 1999 Oct; 8(10):2158-65. PubMed ID: 10548062
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
    Lee CC; Jia Y; Li N; Sun X; Ng K; Ambing E; Gao MY; Hua S; Chen C; Kim S; Michellys PY; Lesley SA; Harris JL; Spraggon G
    Biochem J; 2010 Sep; 430(3):425-37. PubMed ID: 20632993
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An investigation of the role of Glu-842, Glu-844 and His-846 in the function of the cytoplasmic domain of the epidermal growth factor receptor.
    Timms JF; Noble ME; Gregoriou M
    Biochem J; 1995 May; 308 ( Pt 1)(Pt 1):219-29. PubMed ID: 7755568
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of the insulin receptor's kinase domain changes the rate-determining step of substrate phosphorylation.
    Ablooglu AJ; Kohanski RA
    Biochemistry; 2001 Jan; 40(2):504-13. PubMed ID: 11148045
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Investigation of the catalytic site within the ATP-grasp domain of Clostridium symbiosum pyruvate phosphate dikinase.
    Ye D; Wei M; McGuire M; Huang K; Kapadia G; Herzberg O; Martin BM; Dunaway-Mariano D
    J Biol Chem; 2001 Oct; 276(40):37630-9. PubMed ID: 11468288
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-function analysis of the reactive site in the first Kunitz-type domain of human tissue factor pathway inhibitor-2.
    Chand HS; Schmidt AE; Bajaj SP; Kisiel W
    J Biol Chem; 2004 Apr; 279(17):17500-7. PubMed ID: 14970225
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket.
    Villa F; Deak M; Bloomberg GB; Alessi DR; van Aalten DM
    J Biol Chem; 2005 Mar; 280(9):8180-7. PubMed ID: 15611135
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Autophosphorylation dependent destabilization of the insulin receptor kinase domain: tryptophan-1175 reports changes in the catalytic cleft.
    Bishop SM; Ross JB; Kohanski RA
    Biochemistry; 1999 Mar; 38(10):3079-89. PubMed ID: 10074361
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chemical rescue of a mutant protein-tyrosine kinase.
    Williams DM; Wang D; Cole PA
    J Biol Chem; 2000 Dec; 275(49):38127-30. PubMed ID: 11006267
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ligand regulates epidermal growth factor receptor kinase specificity: activation increases preference for GAB1 and SHC versus autophosphorylation sites.
    Fan YX; Wong L; Deb TB; Johnson GR
    J Biol Chem; 2004 Sep; 279(37):38143-50. PubMed ID: 15231819
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Active mutants of the human p38alpha mitogen-activated protein kinase.
    Diskin R; Askari N; Capone R; Engelberg D; Livnah O
    J Biol Chem; 2004 Nov; 279(45):47040-9. PubMed ID: 15284239
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA recognition by the homing endonuclease PI-SceI involves a divalent metal ion cofactor-induced conformational change.
    Noël AJ; Wende W; Pingoud A
    J Biol Chem; 2004 Feb; 279(8):6794-804. PubMed ID: 14634013
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cross-talk between thiamin diphosphate binding and phosphorylation loop conformation in human branched-chain alpha-keto acid decarboxylase/dehydrogenase.
    Li J; Wynn RM; Machius M; Chuang JL; Karthikeyan S; Tomchick DR; Chuang DT
    J Biol Chem; 2004 Jul; 279(31):32968-78. PubMed ID: 15166214
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Arginine residues in the active site of human phenol sulfotransferase (SULT1A1).
    Chen G; Chen X
    J Biol Chem; 2003 Sep; 278(38):36358-64. PubMed ID: 12867416
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Catalytic independent functions of a protein kinase as revealed by a kinase-dead mutant: study of the Lys72His mutant of cAMP-dependent kinase.
    Iyer GH; Garrod S; Woods VL; Taylor SS
    J Mol Biol; 2005 Sep; 351(5):1110-22. PubMed ID: 16054648
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase.
    Atwell S; Adams JM; Badger J; Buchanan MD; Feil IK; Froning KJ; Gao X; Hendle J; Keegan K; Leon BC; Müller-Dieckmann HJ; Nienaber VL; Noland BW; Post K; Rajashankar KR; Ramos A; Russell M; Burley SK; Buchanan SG
    J Biol Chem; 2004 Dec; 279(53):55827-32. PubMed ID: 15507431
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.