128 related articles for article (PubMed ID: 11600374)
1. Analysis of antimalarial synergy between bestatin and endoprotease inhibitors using statistical response-surface modelling.
Gavigan CS; Machado SG; Dalton JP; Bell A
Antimicrob Agents Chemother; 2001 Nov; 45(11):3175-81. PubMed ID: 11600374
[TBL] [Abstract][Full Text] [Related]
2. Chemical target validation studies of aminopeptidase in malaria parasites using alpha-aminoalkylphosphonate and phosphonopeptide inhibitors.
Cunningham E; Drag M; Kafarski P; Bell A
Antimicrob Agents Chemother; 2008 Sep; 52(9):3221-8. PubMed ID: 18458130
[TBL] [Abstract][Full Text] [Related]
3. Plasmodium chabaudi chabaudi and P. falciparum: inhibition of aminopeptidase and parasite growth by bestatin and nitrobestatin.
Nankya-Kitaka MF; Curley GP; Gavigan CS; Bell A; Dalton JP
Parasitol Res; 1998 Jul; 84(7):552-8. PubMed ID: 9694371
[TBL] [Abstract][Full Text] [Related]
4. Antimalarial synergy of cysteine and aspartic protease inhibitors.
Semenov A; Olson JE; Rosenthal PJ
Antimicrob Agents Chemother; 1998 Sep; 42(9):2254-8. PubMed ID: 9736544
[TBL] [Abstract][Full Text] [Related]
5. Plasmodium falciparum: effects of proteinase inhibitors on globin hydrolysis by cultured malaria parasites.
Rosenthal PJ
Exp Parasitol; 1995 Mar; 80(2):272-81. PubMed ID: 7895837
[TBL] [Abstract][Full Text] [Related]
6. Overexpression of leucyl aminopeptidase in Plasmodium falciparum parasites. Target for the antimalarial activity of bestatin.
Gardiner DL; Trenholme KR; Skinner-Adams TS; Stack CM; Dalton JP
J Biol Chem; 2006 Jan; 281(3):1741-5. PubMed ID: 16286469
[TBL] [Abstract][Full Text] [Related]
7. KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.
González-Bacerio J; Maluf SEC; Méndez Y; Pascual I; Florent I; Melo PMS; Budu A; Ferreira JC; Moreno E; Carmona AK; Rivera DG; Alonso Del Rivero M; Gazarini ML
Bioorg Med Chem; 2017 Sep; 25(17):4628-4636. PubMed ID: 28728898
[TBL] [Abstract][Full Text] [Related]
8. Roles for two aminopeptidases in vacuolar hemoglobin catabolism in Plasmodium falciparum.
Dalal S; Klemba M
J Biol Chem; 2007 Dec; 282(49):35978-87. PubMed ID: 17895246
[TBL] [Abstract][Full Text] [Related]
9. Stage-specific antimalarial activity of cysteine protease inhibitors.
Shenai BR; Semenov AV; Rosenthal PJ
Biol Chem; 2002 May; 383(5):843-7. PubMed ID: 12108550
[TBL] [Abstract][Full Text] [Related]
10. Plasmodium falciparum: differential sensitivity in vitro to E-64 (cysteine protease inhibitor) and Pepstatin A (aspartyl protease inhibitor).
Bailly E; Jambou R; Savel J; Jaureguiberry G
J Protozool; 1992; 39(5):593-9. PubMed ID: 1522541
[TBL] [Abstract][Full Text] [Related]
11. Simple 1,2-aminoalcohols as strain-specific antimalarial agents.
Howarth J; Lloyd DG
J Antimicrob Chemother; 2000 Oct; 46(4):625-8. PubMed ID: 11020263
[TBL] [Abstract][Full Text] [Related]
12. Aminopeptidases of malaria parasites: new targets for chemotherapy.
Trenholme KR; Brown CL; Skinner-Adams TS; Stack C; Lowther J; To J; Robinson MW; Donnelly SM; Dalton JP; Gardiner DL
Infect Disord Drug Targets; 2010 Jun; 10(3):217-25. PubMed ID: 20334618
[TBL] [Abstract][Full Text] [Related]
13. Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development.
Stack CM; Lowther J; Cunningham E; Donnelly S; Gardiner DL; Trenholme KR; Skinner-Adams TS; Teuscher F; Grembecka J; Mucha A; Kafarski P; Lua L; Bell A; Dalton JP
J Biol Chem; 2007 Jan; 282(3):2069-80. PubMed ID: 17107951
[TBL] [Abstract][Full Text] [Related]
14. Cysteine proteinase inhibitors block early steps in hemoglobin degradation by cultured malaria parasites.
Gamboa de Domínguez ND; Rosenthal PJ
Blood; 1996 May; 87(10):4448-54. PubMed ID: 8639807
[TBL] [Abstract][Full Text] [Related]
15. The role of aminopeptidases in haemoglobin degradation in Plasmodium falciparum-infected erythrocytes.
Gavigan CS; Dalton JP; Bell A
Mol Biochem Parasitol; 2001 Sep; 117(1):37-48. PubMed ID: 11551630
[TBL] [Abstract][Full Text] [Related]
16. Mapping the Pathway and Dynamics of Bestatin Inhibition of the Plasmodium falciparum M1 Aminopeptidase PfA-M1.
Yang W; Riley BT; Lei X; Porebski BT; Kass I; Buckle AM; McGowan S
ChemMedChem; 2018 Dec; 13(23):2504-2513. PubMed ID: 30318749
[TBL] [Abstract][Full Text] [Related]
17. Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds.
Skinner-Adams TS; Lowther J; Teuscher F; Stack CM; Grembecka J; Mucha A; Kafarski P; Trenholme KR; Dalton JP; Gardiner DL
J Med Chem; 2007 Nov; 50(24):6024-31. PubMed ID: 17960925
[TBL] [Abstract][Full Text] [Related]
18. Identification of hemoglobin degradation products in Plasmodium falciparum.
Kamchonwongpaisan S; Samoff E; Meshnick SR
Mol Biochem Parasitol; 1997 Jun; 86(2):179-86. PubMed ID: 9200124
[TBL] [Abstract][Full Text] [Related]
19. Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Drinkwater N; Vinh NB; Mistry SN; Bamert RS; Ruggeri C; Holleran JP; Loganathan S; Paiardini A; Charman SA; Powell AK; Avery VM; McGowan S; Scammells PJ
Eur J Med Chem; 2016 Mar; 110():43-64. PubMed ID: 26807544
[TBL] [Abstract][Full Text] [Related]
20. A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum.
Rosenthal PJ; McKerrow JH; Aikawa M; Nagasawa H; Leech JH
J Clin Invest; 1988 Nov; 82(5):1560-6. PubMed ID: 3053784
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]