BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 11602573)

  • 1. Down-modulation of type 1 interferon responses by receptor cross-competition for a shared Jak kinase.
    Dondi E; Pattyn E; Lutfalla G; Van Ostade X; Uzé G; Pellegrini S; Tavernier J
    J Biol Chem; 2001 Dec; 276(50):47004-12. PubMed ID: 11602573
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase.
    Rani MR; Leaman DW; Han Y; Leung S; Croze E; Fish EN; Wolfman A; Ransohoff RM
    J Biol Chem; 1999 Nov; 274(45):32507-11. PubMed ID: 10542297
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential tyrosine phosphorylation of the IFNAR chain of the type I interferon receptor and of an associated surface protein in response to IFN-alpha and IFN-beta.
    Abramovich C; Shulman LM; Ratovitski E; Harroch S; Tovey M; Eid P; Revel M
    EMBO J; 1994 Dec; 13(24):5871-7. PubMed ID: 7813427
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer cells.
    Tai Z; Lin Y; He Y; Huang J; Guo J; Yang L; Zhang G; Wang F
    Cell Signal; 2014 Mar; 26(3):619-28. PubMed ID: 24333668
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction.
    Yan H; Krishnan K; Lim JT; Contillo LG; Krolewski JJ
    Mol Cell Biol; 1996 May; 16(5):2074-82. PubMed ID: 8628273
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The antiviral action of interferon is potentiated by removal of the conserved IRTAM domain of the IFNAR1 chain of the interferon alpha/beta receptor: effects on JAK-STAT activation and receptor down-regulation.
    Basu L; Yang CH; Murti A; Garcia JV; Croze E; Constantinescu SN; Mullersman JE; Pfeffer LM
    Virology; 1998 Mar; 242(1):14-21. PubMed ID: 9501047
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The neutralization of type I IFN biologic actions by anti-IFNAR-2 monoclonal antibodies is not entirely due to inhibition of Jak-Stat tyrosine phosphorylation.
    Novick D; Nabioullin RR; Ragsdale W; McKenna S; Weiser W; Garone L; Burkins C; Kim SH; Rubinstein M; Tepper MA; Arulanandam AR
    J Interferon Cytokine Res; 2000 Nov; 20(11):971-82. PubMed ID: 11096454
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C.
    Radaeva S; Jaruga B; Kim WH; Heller T; Liang TJ; Gao B
    Biochem J; 2004 Apr; 379(Pt 1):199-208. PubMed ID: 14690454
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1.
    Richter MF; Duménil G; Uzé G; Fellous M; Pellegrini S
    J Biol Chem; 1998 Sep; 273(38):24723-9. PubMed ID: 9733772
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.
    Ragimbeau J; Dondi E; Alcover A; Eid P; Uzé G; Pellegrini S
    EMBO J; 2003 Feb; 22(3):537-47. PubMed ID: 12554654
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The proximal tyrosines of the cytoplasmic domain of the beta chain of the type I interferon receptor are essential for signal transducer and activator of transcription (Stat) 2 activation. Evidence that two Stat2 sites are required to reach a threshold of interferon alpha-induced Stat2 tyrosine phosphorylation that allows normal formation of interferon-stimulated gene factor 3.
    Nadeau OW; Domanski P; Usacheva A; Uddin S; Platanias LC; Pitha P; Raz R; Levy D; Majchrzak B; Fish E; Colamonici OR
    J Biol Chem; 1999 Feb; 274(7):4045-52. PubMed ID: 9933596
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TYK2 activity promotes ligand-induced IFNAR1 proteolysis.
    Marijanovic Z; Ragimbeau J; Kumar KG; Fuchs SY; Pellegrini S
    Biochem J; 2006 Jul; 397(1):31-8. PubMed ID: 16551269
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase.
    Colamonici O; Yan H; Domanski P; Handa R; Smalley D; Mullersman J; Witte M; Krishnan K; Krolewski J
    Mol Cell Biol; 1994 Dec; 14(12):8133-42. PubMed ID: 7526154
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Definition of the interferon-alpha receptor-binding domain on the TYK2 kinase.
    Yan H; Piazza F; Krishnan K; Pine R; Krolewski JJ
    J Biol Chem; 1998 Feb; 273(7):4046-51. PubMed ID: 9461596
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor.
    Gauzzi MC; Barbieri G; Richter MF; Uzé G; Ling L; Fellous M; Pellegrini S
    Proc Natl Acad Sci U S A; 1997 Oct; 94(22):11839-44. PubMed ID: 9342324
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dimerization of a chimeric CD4-interferon-alpha receptor reconstitutes the signaling events preceding STAT phosphorylation.
    Krishnan K; Yan H; Lim JT; Krolewski JJ
    Oncogene; 1996 Jul; 13(1):125-33. PubMed ID: 8700538
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Constitutive STAT1 tyrosine phosphorylation in U937 monocytes overexpressing the TYK2 protein tyrosine kinase does not induce gene transcription.
    Eilers A; Kanda K; Klose B; Krolewski J; Decker T
    Cell Growth Differ; 1996 Jun; 7(6):833-40. PubMed ID: 8780896
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.
    Velazquez L; Mogensen KE; Barbieri G; Fellous M; Uzé G; Pellegrini S
    J Biol Chem; 1995 Feb; 270(7):3327-34. PubMed ID: 7531704
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Configuration of the interferon-alpha/beta receptor complex determines the context of the biological response.
    Ghislain J; Sussman G; Goelz S; Ling LE; Fish EN
    J Biol Chem; 1995 Sep; 270(37):21785-92. PubMed ID: 7665599
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist.
    Best SM; Morris KL; Shannon JG; Robertson SJ; Mitzel DN; Park GS; Boer E; Wolfinbarger JB; Bloom ME
    J Virol; 2005 Oct; 79(20):12828-39. PubMed ID: 16188985
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.