These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

288 related articles for article (PubMed ID: 11604031)

  • 41. Structure-based generation of viable leads from small combinatorial libraries.
    Laird ER; Blake JF
    Curr Opin Drug Discov Devel; 2004 May; 7(3):354-9. PubMed ID: 15216940
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Novel technologies for virtual screening.
    Lengauer T; Lemmen C; Rarey M; Zimmermann M
    Drug Discov Today; 2004 Jan; 9(1):27-34. PubMed ID: 14761803
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase.
    Dayam R; Sanchez T; Neamati N
    J Med Chem; 2005 Dec; 48(25):8009-15. PubMed ID: 16335925
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Natural product-like libraries based on non-aromatic, polycyclic motifs.
    Messer R; Fuhrer CA; Häner R
    Curr Opin Chem Biol; 2005 Jun; 9(3):259-65. PubMed ID: 15939327
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Drug- and lead-likeness, target class, and molecular diversity analysis of 7.9 million commercially available organic compounds provided by 29 suppliers.
    Chuprina A; Lukin O; Demoiseaux R; Buzko A; Shivanyuk A
    J Chem Inf Model; 2010 Apr; 50(4):470-9. PubMed ID: 20297844
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Current practices in generation of small molecule new leads.
    Goodnow RA
    J Cell Biochem Suppl; 2001; Suppl 37():13-21. PubMed ID: 11842423
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Drug discovery: a historical perspective.
    Drews J
    Science; 2000 Mar; 287(5460):1960-4. PubMed ID: 10720314
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Current progress in natural product-like libraries for discovery screening.
    Tan DS
    Comb Chem High Throughput Screen; 2004 Nov; 7(7):631-43. PubMed ID: 15578925
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Combinatorial chemistry as a tool for drug discovery.
    Floyd CD; Leblanc C; Whittaker M
    Prog Med Chem; 1999; 36():91-168. PubMed ID: 10818672
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Chemical feature-based pharmacophores and virtual library screening for discovery of new leads.
    Langer T; Krovat EM
    Curr Opin Drug Discov Devel; 2003 May; 6(3):370-6. PubMed ID: 12833670
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Ligand-based pharmacophore detection, screening of potential gliptins and docking studies to get effective antidiabetic agents.
    Agrawal R; Jain P; Dikshit SN
    Comb Chem High Throughput Screen; 2012 Dec; 15(10):849-76. PubMed ID: 23140189
    [TBL] [Abstract][Full Text] [Related]  

  • 52. An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmes.
    Albert JS; Blomberg N; Breeze AL; Brown AJ; Burrows JN; Edwards PD; Folmer RH; Geschwindner S; Griffen EJ; Kenny PW; Nowak T; Olsson LL; Sanganee H; Shapiro AB
    Curr Top Med Chem; 2007; 7(16):1600-29. PubMed ID: 17979771
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Designing active template molecules by combining computational de novo design and human chemist's expertise.
    Lameijer EW; Tromp RA; Spanjersberg RF; Brussee J; Ijzerman AP
    J Med Chem; 2007 Apr; 50(8):1925-32. PubMed ID: 17367122
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Lead optimization via high-throughput molecular docking.
    Joseph-McCarthy D; Baber JC; Feyfant E; Thompson DC; Humblet C
    Curr Opin Drug Discov Devel; 2007 May; 10(3):264-74. PubMed ID: 17554852
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Ultrafast de novo docking combining pharmacophores and combinatorics.
    Gastreich M; Lilienthal M; Briem H; Claussen H
    J Comput Aided Mol Des; 2006 Dec; 20(12):717-34. PubMed ID: 17265098
    [TBL] [Abstract][Full Text] [Related]  

  • 56. ADME evaluation in drug discovery. 5. Correlation of Caco-2 permeation with simple molecular properties.
    Hou TJ; Zhang W; Xia K; Qiao XB; Xu XJ
    J Chem Inf Comput Sci; 2004; 44(5):1585-600. PubMed ID: 15446816
    [TBL] [Abstract][Full Text] [Related]  

  • 57. A comparison of physiochemical property profiles of development and marketed oral drugs.
    Wenlock MC; Austin RP; Barton P; Davis AM; Leeson PD
    J Med Chem; 2003 Mar; 46(7):1250-6. PubMed ID: 12646035
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Strategies for rapid deconvolution of combinational libraries: comparative evaluation using a model system.
    Konings DA; Wyatt JR; Ecker DJ; Freier SM
    J Med Chem; 1997 Dec; 40(26):4386-95. PubMed ID: 9435908
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Recent trends in library design: 'rational design' revisited.
    Schnur DM
    Curr Opin Drug Discov Devel; 2008 May; 11(3):375-80. PubMed ID: 18428091
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates.
    Xiao Z; Morris-Natschke SL; Lee KH
    Med Res Rev; 2016 Jan; 36(1):32-91. PubMed ID: 26359649
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.