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8. Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis. Yang QH; Church-Hajduk R; Ren J; Newton ML; Du C Genes Dev; 2003 Jun; 17(12):1487-96. PubMed ID: 12815069 [TBL] [Abstract][Full Text] [Related]
9. Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease. Challa M; Malladi S; Pellock BJ; Dresnek D; Varadarajan S; Yin YW; White K; Bratton SB EMBO J; 2007 Jul; 26(13):3144-56. PubMed ID: 17557079 [TBL] [Abstract][Full Text] [Related]
10. Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice. Martins LM; Morrison A; Klupsch K; Fedele V; Moisoi N; Teismann P; Abuin A; Grau E; Geppert M; Livi GP; Creasy CL; Martin A; Hargreaves I; Heales SJ; Okada H; Brandner S; Schulz JB; Mak T; Downward J Mol Cell Biol; 2004 Nov; 24(22):9848-62. PubMed ID: 15509788 [TBL] [Abstract][Full Text] [Related]
11. Autocatalytic processing of HtrA2/Omi is essential for induction of caspase-dependent cell death through antagonizing XIAP. Seong YM; Choi JY; Park HJ; Kim KJ; Ahn SG; Seong GH; Kim IK; Kang S; Rhim H J Biol Chem; 2004 Sep; 279(36):37588-96. PubMed ID: 15201285 [TBL] [Abstract][Full Text] [Related]
12. The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity. van Loo G; van Gurp M; Depuydt B; Srinivasula SM; Rodriguez I; Alnemri ES; Gevaert K; Vandekerckhove J; Declercq W; Vandenabeele P Cell Death Differ; 2002 Jan; 9(1):20-6. PubMed ID: 11803371 [TBL] [Abstract][Full Text] [Related]
13. Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi. Li W; Srinivasula SM; Chai J; Li P; Wu JW; Zhang Z; Alnemri ES; Shi Y Nat Struct Biol; 2002 Jun; 9(6):436-41. PubMed ID: 11967569 [TBL] [Abstract][Full Text] [Related]
14. Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15. Trencia A; Fiory F; Maitan MA; Vito P; Barbagallo AP; Perfetti A; Miele C; Ungaro P; Oriente F; Cilenti L; Zervos AS; Formisano P; Beguinot F J Biol Chem; 2004 Nov; 279(45):46566-72. PubMed ID: 15328349 [TBL] [Abstract][Full Text] [Related]
15. Omi/HtrA2 Regulates a Mitochondria-Dependent Apoptotic Pathway in a Murine Model of Septic Encephalopathy. Wang P; Hu Y; Yao D; Li Y Cell Physiol Biochem; 2018; 49(6):2163-2173. PubMed ID: 30286467 [TBL] [Abstract][Full Text] [Related]
16. Variations in the protein level of Omi/HtrA2 in the heart of aged rats may contribute to the increased susceptibility of cardiomyocytes to ischemia/reperfusion injury and cell death : Omi/HtrA2 and aged heart injury. Wang K; Zhang J; Liu J; Tian J; Wu Y; Wang X; Quan L; Xu H; Wang W; Liu H Age (Dordr); 2013 Jun; 35(3):733-46. PubMed ID: 22535253 [TBL] [Abstract][Full Text] [Related]
17. Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway. Srinivasula SM; Datta P; Fan XJ; Fernandes-Alnemri T; Huang Z; Alnemri ES J Biol Chem; 2000 Nov; 275(46):36152-7. PubMed ID: 10950947 [TBL] [Abstract][Full Text] [Related]
18. Akt attenuation of the serine protease activity of HtrA2/Omi through phosphorylation of serine 212. Yang L; Sun M; Sun XM; Cheng GZ; Nicosia SV; Cheng JQ J Biol Chem; 2007 Apr; 282(15):10981-7. PubMed ID: 17311912 [TBL] [Abstract][Full Text] [Related]
19. Translocation of the serine protease Omi/HtrA2 from mitochondria into the cytosol upon seizure-induced hippocampal injury in the neonatal rat brain. Rami A; Kim M; Niquet J Neurochem Res; 2010 Dec; 35(12):2199-207. PubMed ID: 21132459 [TBL] [Abstract][Full Text] [Related]
20. Expression of AIF and HtrA2/Omi in small lymphocytic lymphoma and diffuse large B-cell lymphoma. Li S; Wan M; Cao X; Ren Y Arch Pathol Lab Med; 2011 Jul; 135(7):903-8. PubMed ID: 21732781 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]