These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 11641236)

  • 1. Defects of the insulin receptor substrate (IRS) system in human metabolic disorders.
    Sesti G; Federici M; Hribal ML; Lauro D; Sbraccia P; Lauro R
    FASEB J; 2001 Oct; 15(12):2099-111. PubMed ID: 11641236
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin receptor substrate polymorphisms and type 2 diabetes mellitus.
    Sesti G
    Pharmacogenomics; 2000 Aug; 1(3):343-57. PubMed ID: 11256583
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential.
    Giovannone B; Scaldaferri ML; Federici M; Porzio O; Lauro D; Fusco A; Sbraccia P; Borboni P; Lauro R; Sesti G
    Diabetes Metab Res Rev; 2000; 16(6):434-41. PubMed ID: 11114102
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.
    Kubota N; Tobe K; Terauchi Y; Eto K; Yamauchi T; Suzuki R; Tsubamoto Y; Komeda K; Nakano R; Miki H; Satoh S; Sekihara H; Sciacchitano S; Lesniak M; Aizawa S; Nagai R; Kimura S; Akanuma Y; Taylor SI; Kadowaki T
    Diabetes; 2000 Nov; 49(11):1880-9. PubMed ID: 11078455
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of IRS-2 causes type 2 diabetes in mice.
    Withers DJ; Gutierrez JS; Towery H; Burks DJ; Ren JM; Previs S; Zhang Y; Bernal D; Pons S; Shulman GI; Bonner-Weir S; White MF
    Nature; 1998 Feb; 391(6670):900-4. PubMed ID: 9495343
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules.
    Tanaka S; Ito T; Wands JR
    J Biol Chem; 1996 Jun; 271(24):14610-6. PubMed ID: 8662827
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.
    Kido Y; Burks DJ; Withers D; Bruning JC; Kahn CR; White MF; Accili D
    J Clin Invest; 2000 Jan; 105(2):199-205. PubMed ID: 10642598
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Gly-->Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells.
    Hribal ML; Federici M; Porzio O; Lauro D; Borboni P; Accili D; Lauro R; Sesti G
    J Clin Endocrinol Metab; 2000 May; 85(5):2004-13. PubMed ID: 10843189
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice.
    Yamauchi T; Tobe K; Tamemoto H; Ueki K; Kaburagi Y; Yamamoto-Honda R; Takahashi Y; Yoshizawa F; Aizawa S; Akanuma Y; Sonenberg N; Yazaki Y; Kadowaki T
    Mol Cell Biol; 1996 Jun; 16(6):3074-84. PubMed ID: 8649419
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Down-regulation of insulin receptor substrates (IRS)-1 and IRS-2 and Src homologous and collagen-like protein Shc gene expression by insulin in skeletal muscle is not associated with insulin resistance or type 2 diabetes.
    Huang X; Vaag A; Hansson M; Groop L
    J Clin Endocrinol Metab; 2002 Jan; 87(1):255-9. PubMed ID: 11788655
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity.
    Stefan N; Kovacs P; Stumvoll M; Hanson RL; Lehn-Stefan A; Permana PA; Baier LJ; Tataranni PA; Silver K; Bogardus C
    Diabetes; 2003 Jun; 52(6):1544-50. PubMed ID: 12765968
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets.
    Federici M; Hribal ML; Ranalli M; Marselli L; Porzio O; Lauro D; Borboni P; Lauro R; Marchetti P; Melino G; Sesti G
    FASEB J; 2001 Jan; 15(1):22-24. PubMed ID: 11099486
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Common amino acid substitutions in insulin receptor substrate-4 are not associated with Type II diabetes mellitus or insulin resistance.
    Almind K; Frederiksen SK; Ahlgren MG; Urhammer S; Hansen T; Clausen JO; Pedersen O
    Diabetologia; 1998 Aug; 41(8):969-74. PubMed ID: 9726601
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin receptor substrate (IRS) proteins IRS-1 and IRS-2 differential signaling in the insulin/insulin-like growth factor-I pathways in fetal brown adipocytes.
    Valverde AM; Lorenzo M; Pons S; White MF; Benito M
    Mol Endocrinol; 1998 May; 12(5):688-97. PubMed ID: 9605931
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The new elements of insulin signaling. Insulin receptor substrate-1 and proteins with SH2 domains.
    Myers MG; White MF
    Diabetes; 1993 May; 42(5):643-50. PubMed ID: 8387037
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The IR1152 mutant insulin receptor selectively impairs insulin action in skeletal muscle but not in liver.
    Caruso M; Miele C; Oliva A; Condorelli G; Oriente F; Riccardi G; Capaldo B; Fiory F; Accili D; Formisano P; Beguinot F
    Diabetes; 2000 Jul; 49(7):1194-202. PubMed ID: 10909978
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells.
    Brüning JC; Winnay J; Cheatham B; Kahn CR
    Mol Cell Biol; 1997 Mar; 17(3):1513-21. PubMed ID: 9032279
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heterozygous knockout of the IRS-1 gene in mice enhances obesity-linked insulin resistance: a possible model for the development of type 2 diabetes.
    Shirakami A; Toyonaga T; Tsuruzoe K; Shirotani T; Matsumoto K; Yoshizato K; Kawashima J; Hirashima Y; Miyamura N; Kahn CR; Araki E
    J Endocrinol; 2002 Aug; 174(2):309-19. PubMed ID: 12176670
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins.
    Morris DL; Cho KW; Zhou Y; Rui L
    Diabetes; 2009 Sep; 58(9):2039-47. PubMed ID: 19542202
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel T608R missense mutation in insulin receptor substrate-1 identified in a subject with type 2 diabetes impairs metabolic insulin signaling.
    Esposito DL; Li Y; Vanni C; Mammarella S; Veschi S; Della Loggia F; Mariani-Costantini R; Battista P; Quon MJ; Cama A
    J Clin Endocrinol Metab; 2003 Apr; 88(4):1468-75. PubMed ID: 12679424
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.