440 related articles for article (PubMed ID: 11668216)
21. The nuclear pregnane X receptor regulates xenobiotic detoxification.
Kliewer SA
J Nutr; 2003 Jul; 133(7 Suppl):2444S-2447S. PubMed ID: 12840222
[TBL] [Abstract][Full Text] [Related]
22. MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype.
Lamba J; Strom S; Venkataramanan R; Thummel KE; Lin YS; Liu W; Cheng C; Lamba V; Watkins PB; Schuetz E
Clin Pharmacol Ther; 2006 Apr; 79(4):325-38. PubMed ID: 16580901
[TBL] [Abstract][Full Text] [Related]
23. Novel single nucleotide polymorphisms in the promoter and intron 1 of human pregnane X receptor/NR1I2 and their association with CYP3A4 expression.
Lamba J; Lamba V; Strom S; Venkataramanan R; Schuetz E
Drug Metab Dispos; 2008 Jan; 36(1):169-81. PubMed ID: 17925385
[TBL] [Abstract][Full Text] [Related]
24. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
Staudinger J; Liu Y; Madan A; Habeebu S; Klaassen CD
Drug Metab Dispos; 2001 Nov; 29(11):1467-72. PubMed ID: 11602523
[TBL] [Abstract][Full Text] [Related]
25. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
Maglich JM; Stoltz CM; Goodwin B; Hawkins-Brown D; Moore JT; Kliewer SA
Mol Pharmacol; 2002 Sep; 62(3):638-46. PubMed ID: 12181440
[TBL] [Abstract][Full Text] [Related]
26. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.
Lehmann JM; McKee DD; Watson MA; Willson TM; Moore JT; Kliewer SA
J Clin Invest; 1998 Sep; 102(5):1016-23. PubMed ID: 9727070
[TBL] [Abstract][Full Text] [Related]
27. Humanized xenobiotic response in mice expressing nuclear receptor SXR.
Xie W; Barwick JL; Downes M; Blumberg B; Simon CM; Nelson MC; Neuschwander-Tetri BA; Brunt EM; Guzelian PS; Evans RM
Nature; 2000 Jul; 406(6794):435-9. PubMed ID: 10935643
[TBL] [Abstract][Full Text] [Related]
28. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
Moore LB; Parks DJ; Jones SA; Bledsoe RK; Consler TG; Stimmel JB; Goodwin B; Liddle C; Blanchard SG; Willson TM; Collins JL; Kliewer SA
J Biol Chem; 2000 May; 275(20):15122-7. PubMed ID: 10748001
[TBL] [Abstract][Full Text] [Related]
29. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
Tirona RG; Lee W; Leake BF; Lan LB; Cline CB; Lamba V; Parviz F; Duncan SA; Inoue Y; Gonzalez FJ; Schuetz EG; Kim RB
Nat Med; 2003 Feb; 9(2):220-4. PubMed ID: 12514743
[TBL] [Abstract][Full Text] [Related]
30. Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio).
Bainy AC; Kubota A; Goldstone JV; Lille-Langøy R; Karchner SI; Celander MC; Hahn ME; Goksøyr A; Stegeman JJ
Aquat Toxicol; 2013 Oct; 142-143():447-57. PubMed ID: 24121122
[TBL] [Abstract][Full Text] [Related]
31. A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.
Lemaire G; de Sousa G; Rahmani R
Biochem Pharmacol; 2004 Dec; 68(12):2347-58. PubMed ID: 15548381
[TBL] [Abstract][Full Text] [Related]
32. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
Hoffart E; Ghebreghiorghis L; Nussler AK; Thasler WE; Weiss TS; Schwab M; Burk O
Br J Pharmacol; 2012 Mar; 165(5):1595-608. PubMed ID: 21913896
[TBL] [Abstract][Full Text] [Related]
33. Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors.
Anakk S; Kalsotra A; Shen Q; Vu MT; Staudinger JL; Davies PJ; Strobel HW
FASEB J; 2003 Sep; 17(12):1736-8. PubMed ID: 12958193
[TBL] [Abstract][Full Text] [Related]
34. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
35. Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor.
Ripp SL; Fitzpatrick JL; Peters JM; Prough RA
Drug Metab Dispos; 2002 May; 30(5):570-5. PubMed ID: 11950789
[TBL] [Abstract][Full Text] [Related]
36. Screening for polymorphisms in the PXR gene in a Dutch population.
Bosch TM; Deenen M; Pruntel R; Smits PH; Schellens JH; Beijnen JH; Meijerman I
Eur J Clin Pharmacol; 2006 May; 62(5):395-9. PubMed ID: 16568343
[TBL] [Abstract][Full Text] [Related]
37. Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element.
El-Sankary W; Bombail V; Gibson GG; Plant N
Drug Metab Dispos; 2002 Sep; 30(9):1029-34. PubMed ID: 12167569
[TBL] [Abstract][Full Text] [Related]
38. Pharmaceutical use of mouse models humanized for the xenobiotic receptor.
Xie W; Evans RM
Drug Discov Today; 2002 May; 7(9):509-15. PubMed ID: 11983567
[TBL] [Abstract][Full Text] [Related]
39. Role of Sp1, C/EBP alpha, HNF3, and PXR in the basal- and xenobiotic-mediated regulation of the CYP3A4 gene.
Bombail V; Taylor K; Gibson GG; Plant N
Drug Metab Dispos; 2004 May; 32(5):525-35. PubMed ID: 15100175
[TBL] [Abstract][Full Text] [Related]
40. Rat PXR reporter-gene activity correlates with the induction of CYP3A in rat precision-cut liver slices.
Cui X; Thomas A; Montgomery D; Gu C; Morrison RA; White RE; Cheng KC
Comb Chem High Throughput Screen; 2005 Jun; 8(4):341-6. PubMed ID: 16101010
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
