166 related articles for article (PubMed ID: 11673862)
1. Random mutagenesis of human cytochrome p450 2A6 and screening with indole oxidation products.
Nakamura K; Martin MV; Guengerich FP
Arch Biochem Biophys; 2001 Nov; 395(1):25-31. PubMed ID: 11673862
[TBL] [Abstract][Full Text] [Related]
2. Expansion of substrate specificity of cytochrome P450 2A6 by random and site-directed mutagenesis.
Wu ZL; Podust LM; Guengerich FP
J Biol Chem; 2005 Dec; 280(49):41090-100. PubMed ID: 16215230
[TBL] [Abstract][Full Text] [Related]
3. Oxidation of indole by cytochrome P450 enzymes.
Gillam EM; Notley LM; Cai H; De Voss JJ; Guengerich FP
Biochemistry; 2000 Nov; 39(45):13817-24. PubMed ID: 11076521
[TBL] [Abstract][Full Text] [Related]
4. Analysis of coumarin 7-hydroxylation activity of cytochrome P450 2A6 using random mutagenesis.
Kim D; Wu ZL; Guengerich FP
J Biol Chem; 2005 Dec; 280(48):40319-27. PubMed ID: 16207711
[TBL] [Abstract][Full Text] [Related]
5. Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
Park SH; Kim DH; Kim D; Kim DH; Jung HC; Pan JG; Ahn T; Kim D; Yun CH
Drug Metab Dispos; 2010 May; 38(5):732-9. PubMed ID: 20100815
[TBL] [Abstract][Full Text] [Related]
6. Identification of amino acid residues involved in 4-chloroindole 3-hydroxylation by cytochrome P450 2A6 using screening of random libraries.
Zhang ZG; Liu Y; Guengerich FP; Matse JH; Chen J; Wu ZL
J Biotechnol; 2009 Jan; 139(1):12-8. PubMed ID: 18984015
[TBL] [Abstract][Full Text] [Related]
7. Generation of new protein kinase inhibitors utilizing cytochrome p450 mutant enzymes for indigoid synthesis.
Guengerich FP; Sorrells JL; Schmitt S; Krauser JA; Aryal P; Meijer L
J Med Chem; 2004 Jun; 47(12):3236-41. PubMed ID: 15163202
[TBL] [Abstract][Full Text] [Related]
8. Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen.
Koenigs LL; Peter RM; Thompson SJ; Rettie AE; Trager WF
Drug Metab Dispos; 1997 Dec; 25(12):1407-15. PubMed ID: 9394031
[TBL] [Abstract][Full Text] [Related]
9. Biosynthesis of new indigoid inhibitors of protein kinases using recombinant cytochrome P450 2A6.
Wu ZL; Aryal P; Lozach O; Meijer L; Guengerich FP
Chem Biodivers; 2005 Jan; 2(1):51-65. PubMed ID: 17191919
[TBL] [Abstract][Full Text] [Related]
10. Expression of cytochrome P450 2A6 in Escherichia coli: purification, spectral and catalytic characterization, and preparation of polyclonal antibodies.
Soucek P
Arch Biochem Biophys; 1999 Oct; 370(2):190-200. PubMed ID: 10510277
[TBL] [Abstract][Full Text] [Related]
11. Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants.
Sansen S; Hsu MH; Stout CD; Johnson EF
Arch Biochem Biophys; 2007 Aug; 464(2):197-206. PubMed ID: 17540336
[TBL] [Abstract][Full Text] [Related]
12. Cytochrome P450 BM-3 evolved by random and saturation mutagenesis as an effective indole-hydroxylating catalyst.
Li HM; Mei LH; Urlacher VB; Schmid RD
Appl Biochem Biotechnol; 2008 Jan; 144(1):27-36. PubMed ID: 18415984
[TBL] [Abstract][Full Text] [Related]
13. Exploiting the versatility of human cytochrome P450 enzymes: the promise of blue roses from biotechnology.
Gillam EM; Guengerich FP
IUBMB Life; 2001 Dec; 52(6):271-7. PubMed ID: 11895075
[TBL] [Abstract][Full Text] [Related]
14. Kinetic analysis of oxidation of coumarins by human cytochrome P450 2A6.
Yun CH; Kim KH; Calcutt MW; Guengerich FP
J Biol Chem; 2005 Apr; 280(13):12279-91. PubMed ID: 15665333
[TBL] [Abstract][Full Text] [Related]
15. Directed-evolution analysis of human cytochrome P450 2A6 for enhanced enzymatic catalysis.
Lee H; Kim JH; Han S; Lim YR; Park HG; Chun YJ; Park SW; Kim D
J Toxicol Environ Health A; 2014; 77(22-24):1409-18. PubMed ID: 25343290
[TBL] [Abstract][Full Text] [Related]
16. Functional characterization of cytochrome P450 2A6 allelic variants CYP2A6*15, CYP2A6*16, CYP2A6*21, and CYP2A6*22.
Tiong KH; Yiap BC; Tan EL; Ismail R; Ong CE
Drug Metab Dispos; 2010 May; 38(5):745-51. PubMed ID: 20139165
[TBL] [Abstract][Full Text] [Related]
17. Protein engineering of toluene ortho-monooxygenase of Burkholderia cepacia G4 for regiospecific hydroxylation of indole to form various indigoid compounds.
Rui L; Reardon KF; Wood TK
Appl Microbiol Biotechnol; 2005 Jan; 66(4):422-9. PubMed ID: 15290130
[TBL] [Abstract][Full Text] [Related]
18. Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
Spracklin DK; Thummel KE; Kharasch ED
Drug Metab Dispos; 1996 Sep; 24(9):976-83. PubMed ID: 8886607
[TBL] [Abstract][Full Text] [Related]
19. Identification of Val117 and Arg372 as critical amino acid residues for the activity difference between human CYP2A6 and CYP2A13 in coumarin 7-hydroxylation.
He XY; Shen J; Hu WY; Ding X; Lu AY; Hong JY
Arch Biochem Biophys; 2004 Jul; 427(2):143-53. PubMed ID: 15196988
[TBL] [Abstract][Full Text] [Related]
20. Competitive interactions between cytochromes P450 2A6 and 2E1 for NADPH-cytochrome P450 oxidoreductase in the microsomal membranes produced by a baculovirus expression system.
Tan Y; Patten CJ; Smith T; Yang CS
Arch Biochem Biophys; 1997 Jun; 342(1):82-91. PubMed ID: 9185616
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]