BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 11689159)

  • 1. Cholera toxin-B subunit blocks excitatory opioid receptor-mediated hyperalgesic effects in mice, thereby unmasking potent opioid analgesia and attenuating opioid tolerance/dependence.
    Shen KF; Crain SM
    Brain Res; 2001 Nov; 919(1):20-30. PubMed ID: 11689159
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Naloxone rapidly evokes endogenous kappa opioid receptor-mediated hyperalgesia in naïve mice pretreated briefly with GM1 ganglioside or in chronic morphine-dependent mice.
    Crain SM; Shen KF
    Brain Res; 2007 Sep; 1167():31-41. PubMed ID: 17692296
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ultra-low doses of naltrexone or etorphine increase morphine's antinociceptive potency and attenuate tolerance/dependence in mice.
    Shen KF; Crain SM
    Brain Res; 1997 May; 757(2):176-90. PubMed ID: 9200746
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Acute thermal hyperalgesia elicited by low-dose morphine in normal mice is blocked by ultra-low-dose naltrexone, unmasking potent opioid analgesia.
    Crain SM; Shen KF
    Brain Res; 2001 Jan; 888(1):75-82. PubMed ID: 11146054
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ultra-low concentrations of naloxone selectively antagonize excitatory effects of morphine on sensory neurons, thereby increasing its antinociceptive potency and attenuating tolerance/dependence during chronic cotreatment.
    Crain SM; Shen KF
    Proc Natl Acad Sci U S A; 1995 Nov; 92(23):10540-4. PubMed ID: 7479836
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Low doses of cyclic AMP-phosphodiesterase inhibitors rapidly evoke opioid receptor-mediated thermal hyperalgesia in naïve mice which is converted to prominent analgesia by cotreatment with ultra-low-dose naltrexone.
    Crain SM; Shen KF
    Brain Res; 2008 Sep; 1231():16-24. PubMed ID: 18656459
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neuraminidase inhibitor, oseltamivir blocks GM1 ganglioside-regulated excitatory opioid receptor-mediated hyperalgesia, enhances opioid analgesia and attenuates tolerance in mice.
    Crain SM; Shen KF
    Brain Res; 2004 Jan; 995(2):260-6. PubMed ID: 14672816
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cholera toxin-B subunit blocks excitatory effects of opioids on sensory neuron action potentials indicating that GM1 ganglioside may regulate Gs-linked opioid receptor functions.
    Shen KF; Crain SM
    Brain Res; 1990 Oct; 531(1-2):1-7. PubMed ID: 1981160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Etorphine elicits anomalous excitatory opioid effects on sensory neurons treated with GM1 ganglioside or pertussis toxin in contrast to its potent inhibitory effects on naive or chronic morphine-treated cells.
    Crain SM; Shen KF
    Brain Res; 1996 Nov; 741(1-2):275-83. PubMed ID: 9001733
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Morphine hyperalgesia in mice is unrelated to opioid activity, analgesia, or tolerance: evidence for multiple diverse hyperalgesic systems.
    Juni A; Klein G; Kest B
    Brain Res; 2006 Jan; 1070(1):35-44. PubMed ID: 16409995
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antagonists at excitatory opioid receptors on sensory neurons in culture increase potency and specificity of opiate analgesics and attenuate development of tolerance/dependence.
    Shen KF; Crain SM
    Brain Res; 1994 Feb; 636(2):286-97. PubMed ID: 8012813
    [TBL] [Abstract][Full Text] [Related]  

  • 12. GM1 ganglioside-induced modulation of opioid receptor-mediated functions.
    Crain SM; Shen KF
    Ann N Y Acad Sci; 1998 Jun; 845():106-25. PubMed ID: 9668346
    [TBL] [Abstract][Full Text] [Related]  

  • 13. After chronic opioid exposure sensory neurons become supersensitive to the excitatory effects of opioid agonists and antagonists as occurs after acute elevation of GM1 ganglioside.
    Crain SM; Shen KF
    Brain Res; 1992 Mar; 575(1):13-24. PubMed ID: 1324084
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antagonists of excitatory opioid receptor functions enhance morphine's analgesic potency and attenuate opioid tolerance/dependence liability.
    Crain SM; Shen KF
    Pain; 2000 Feb; 84(2-3):121-31. PubMed ID: 10666516
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Brief treatment of sensory ganglion neurons with GM1 ganglioside enhances the efficacy of opioid excitatory effects on the action potential.
    Shen KF; Crain SM; Ledeen RW
    Brain Res; 1991 Sep; 559(1):130-8. PubMed ID: 1685937
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modulatory effects of Gs-coupled excitatory opioid receptor functions on opioid analgesia, tolerance, and dependence.
    Crain SM; Shen KF
    Neurochem Res; 1996 Nov; 21(11):1347-51. PubMed ID: 8947924
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biphalin, an enkephalin analog with unexpectedly high antinociceptive potency and low dependence liability in vivo, selectively antagonizes excitatory opioid receptor functions of sensory neurons in culture.
    Shen KF; Crain SM
    Brain Res; 1995 Dec; 701(1-2):158-66. PubMed ID: 8925279
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced analgesic potency and reduced tolerance of morphine in 129/SvEv mice: evidence for a deficiency in GM1 ganglioside-regulated excitatory opioid receptor functions.
    Crain SM; Shen K
    Brain Res; 2000 Feb; 856(1-2):227-35. PubMed ID: 10677630
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chronic selective activation of excitatory opioid receptor functions in sensory neurons results in opioid 'dependence' without tolerance.
    Shen KF; Crain SM
    Brain Res; 1992 Nov; 597(1):74-83. PubMed ID: 1335822
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Paradoxical effects of the opioid antagonist naltrexone on morphine analgesia, tolerance, and reward in rats.
    Powell KJ; Abul-Husn NS; Jhamandas A; Olmstead MC; Beninger RJ; Jhamandas K
    J Pharmacol Exp Ther; 2002 Feb; 300(2):588-96. PubMed ID: 11805221
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.