BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 11695551)

  • 1. Is p53 haploinsufficient for tumor suppression? Implications for the p53+/- mouse model in carcinogenicity testing.
    Venkatachalam S; Tyner SD; Pickering CR; Boley S; Recio L; French JE; Donehower LA
    Toxicol Pathol; 2001; 29 Suppl():147-54. PubMed ID: 11695551
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The nature of the heterozygous Trp53 knockout model for identification of mutagenic carcinogens.
    French J; Storer RD; Donehower LA
    Toxicol Pathol; 2001; 29 Suppl():24-9. PubMed ID: 11695559
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of heterozygosity frequency at the Trp53 locus in p53-deficient (+/-) mouse tumors is carcinogen-and tissue-dependent.
    French JE; Lacks GD; Trempus C; Dunnick JK; Foley J; Mahler J; Tice RR; Tennant RW
    Carcinogenesis; 2001 Jan; 22(1):99-106. PubMed ID: 11159747
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA repair-deficient Xpa and Xpa/p53+/- knock-out mice: nature of the models.
    van Steeg H; de Vries A; van Oostrom CTh ; van Benthem J; Beems RB; van Kreijl CF
    Toxicol Pathol; 2001; 29 Suppl():109-16. PubMed ID: 11695546
    [TBL] [Abstract][Full Text] [Related]  

  • 5. P53+/- hemizygous knockout mouse: overview of available data.
    Storer RD; French JE; Haseman J; Hajian G; LeGrand EK; Long GG; Mixson LA; Ochoa R; Sagartz JE; Soper KA
    Toxicol Pathol; 2001; 29 Suppl():30-50. PubMed ID: 11695560
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Xpa and Xpa/p53+/- knockout mice: overview of available data.
    van Kreijl CF; McAnulty PA; Beems RB; Vynckier A; van Steeg H; Fransson-Steen R; Alden CL; Forster R; van der Laan JW; Vandenberghe J
    Toxicol Pathol; 2001; 29 Suppl():117-27. PubMed ID: 11695547
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation.
    Venkatachalam S; Shi YP; Jones SN; Vogel H; Bradley A; Pinkel D; Donehower LA
    EMBO J; 1998 Aug; 17(16):4657-67. PubMed ID: 9707425
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chromosome 11 allelotypes reflect a mechanism of chemical carcinogenesis in heterozygous p53-deficient mice.
    Hulla JE; French JE; Dunnick JK
    Carcinogenesis; 2001 Jan; 22(1):89-98. PubMed ID: 11159746
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alternative models for carcinogenicity testing: weight of evidence evaluations across models.
    Cohen SM
    Toxicol Pathol; 2001; 29 Suppl():183-90. PubMed ID: 11695556
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heterozygous p53-deficient mice are not susceptible to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) carcinogenicity.
    Park CB; Kim DJ; Uehara N; Takasuka N; Hiroyasu BT; Tsuda H
    Cancer Lett; 1999 May; 139(2):177-82. PubMed ID: 10395176
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanisms of hormonal carcinogenesis in the p53+/- hemizygous knockout mouse: studies with diethylstilbestrol.
    Carmichael PL; Mills JJ; Campbell M; Basu M; Caldwell J
    Toxicol Pathol; 2001; 29 Suppl():155-60. PubMed ID: 11695552
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of heterozygous loss of p53 on benzo[a]pyrene-induced mutations and tumors in DNA repair-deficient XPA mice.
    van Oostrom CT; Boeve M; van Den Berg J; de Vries A; Dollé ME; Beems RB; van Kreijl CF; Vijg J; van Steeg H
    Environ Mol Mutagen; 1999; 34(2-3):124-30. PubMed ID: 10529736
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased tumor cell proliferation in murine tumors with decreasing dosage of wild-type p53.
    Tyner SD; Choi J; Laucirica R; Ford RJ; Donehower LA
    Mol Carcinog; 1999 Mar; 24(3):197-208. PubMed ID: 10204804
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Use of p53 transgenic mice in the development of cancer models for multiple purposes.
    Lubet RA; Zhang Z; Wiseman RW; You M
    Exp Lung Res; 2000 Dec; 26(8):581-93. PubMed ID: 11195457
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A perspective on current and future uses of alternative models for carcinogenicity testing.
    Goodman JI
    Toxicol Pathol; 2001; 29 Suppl():173-6. PubMed ID: 11695554
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Detection of genotoxic and non-genotoxic carcinogens in Xpc(-/-)p53(+/-) mice.
    Melis JP; Speksnijder EN; Kuiper RV; Salvatori DC; Schaap MM; Maas S; Robinson J; Verhoef A; van Benthem J; Luijten M; van Steeg H
    Toxicol Appl Pharmacol; 2013 Jan; 266(2):289-97. PubMed ID: 23153559
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neonatal mouse model: review of methods and results.
    McClain RM; Keller D; Casciano D; Fu P; MacDonald J; Popp J; Sagartz J
    Toxicol Pathol; 2001; 29 Suppl():128-37. PubMed ID: 11695548
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetically altered mouse models for identifying carcinogens.
    Tennant RW; Stasiewicz S; Mennear J; French JE; Spalding JW
    IARC Sci Publ; 1999; (146):123-50. PubMed ID: 10353386
    [No Abstract]   [Full Text] [Related]  

  • 19. Use of transgenic animals for carcinogenicity testing: considerations and implications for risk assessment.
    Gulezian D; Jacobson-Kram D; McCullough CB; Olson H; Recio L; Robinson D; Storer R; Tennant R; Ward JM; Neumann DA
    Toxicol Pathol; 2000; 28(3):482-99. PubMed ID: 10862569
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CB6F1-rasH2 mouse: overview of available data.
    Usui T; Mutai M; Hisada S; Takoaka M; Soper KA; McCullough B; Alden C
    Toxicol Pathol; 2001; 29 Suppl():90-108. PubMed ID: 11695565
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.