BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

508 related articles for article (PubMed ID: 11695848)

  • 1. Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin.
    Hanioka N; Ozawa S; Jinno H; Ando M; Saito Y; Sawada J
    Xenobiotica; 2001 Oct; 31(10):687-99. PubMed ID: 11695848
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Glucuronidation of etoposide in human liver microsomes is specifically catalyzed by UDP-glucuronosyltransferase 1A1.
    Watanabe Y; Nakajima M; Ohashi N; Kume T; Yokoi T
    Drug Metab Dispos; 2003 May; 31(5):589-95. PubMed ID: 12695347
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Involvement of multiple UDP-glucuronosyltransferase 1A isoforms in glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes.
    Nakajima M; Sakata N; Ohashi N; Kume T; Yokoi T
    Drug Metab Dispos; 2002 Nov; 30(11):1250-6. PubMed ID: 12386132
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Troglitazone glucuronidation in human liver and intestine microsomes: high catalytic activity of UGT1A8 and UGT1A10.
    Watanabe Y; Nakajima M; Yokoi T
    Drug Metab Dispos; 2002 Dec; 30(12):1462-9. PubMed ID: 12433820
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).
    Gagné JF; Montminy V; Belanger P; Journault K; Gaucher G; Guillemette C
    Mol Pharmacol; 2002 Sep; 62(3):608-17. PubMed ID: 12181437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of human UDP-glucuronosyltransferase isoform(s) responsible for the glucuronidation of 2-(4-chlorophenyl)- 5-(2-furyl)-4-oxazoleacetic acid (TA-1801A).
    Kaji H; Kume T
    Drug Metab Pharmacokinet; 2005 Jun; 20(3):212-8. PubMed ID: 15988124
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human UDP-glucuronosyltransferase isoforms involved in bisphenol A glucuronidation.
    Hanioka N; Naito T; Narimatsu S
    Chemosphere; 2008 Dec; 74(1):33-6. PubMed ID: 18990428
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New Insights into SN-38 Glucuronidation: Evidence for the Important Role of UDP Glucuronosyltransferase 1A9.
    Xiao L; Zhu L; Li W; Li C; Cao Y; Ge G; Sun X
    Basic Clin Pharmacol Toxicol; 2018 Apr; 122(4):424-428. PubMed ID: 29076612
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms.
    Court MH; Duan SX; von Moltke LL; Greenblatt DJ; Patten CJ; Miners JO; Mackenzie PI
    J Pharmacol Exp Ther; 2001 Dec; 299(3):998-1006. PubMed ID: 11714888
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4.
    Aprile S; Del Grosso E; Grosa G
    Drug Metab Dispos; 2010 Jul; 38(7):1141-6. PubMed ID: 20375181
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glucuronidation of DRF-6574, hydroxy metabolite of DRF-4367 (a novel COX-2 inhibitor) by pooled human liver, intestinal microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT1A1, 1A3 and 1A8.
    Muzeeb S; Basha SJ; Shashikumar D; Mullangi R; Srinivas NR
    Eur J Drug Metab Pharmacokinet; 2006; 31(4):299-309. PubMed ID: 17315542
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of niflumic acid as a selective inhibitor of human liver microsomal UDP-glucuronosyltransferase 1A9: application to the reaction phenotyping of acetaminophen glucuronidation.
    Miners JO; Bowalgaha K; Elliot DJ; Baranczewski P; Knights KM
    Drug Metab Dispos; 2011 Apr; 39(4):644-52. PubMed ID: 21245288
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans.
    Kato Y; Ikushiro S; Emi Y; Tamaki S; Suzuki H; Sakaki T; Yamada S; Degawa M
    Drug Metab Dispos; 2008 Jan; 36(1):51-5. PubMed ID: 17908920
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
    Ma L; Sun J; Peng Y; Zhang R; Shao F; Hu X; Zhu J; Wang X; Cheng X; Zhu Y; Wan P; Feng D; Wu H; Wang G
    Drug Metab Dispos; 2012 Apr; 40(4):734-41. PubMed ID: 22238289
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver.
    Girard H; Villeneuve L; Court MH; Fortier LC; Caron P; Hao Q; von Moltke LL; Greenblatt DJ; Guillemette C
    Drug Metab Dispos; 2006 Jul; 34(7):1220-8. PubMed ID: 16595709
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes.
    Yong WP; Ramirez J; Innocenti F; Ratain MJ
    Clin Cancer Res; 2005 Sep; 11(18):6699-704. PubMed ID: 16166450
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acyl glucuronidation of fluoroquinolone antibiotics by the UDP-glucuronosyltransferase 1A subfamily in human liver microsomes.
    Tachibana M; Tanaka M; Masubuchi Y; Horie T
    Drug Metab Dispos; 2005 Jun; 33(6):803-11. PubMed ID: 15769885
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D.
    Jinno H; Tanaka-Kagawa T; Hanioka N; Saeki M; Ishida S; Nishimura T; Ando M; Saito Y; Ozawa S; Sawada J
    Drug Metab Dispos; 2003 Jan; 31(1):108-13. PubMed ID: 12485959
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential rates of glucuronidation for 7-ethyl-10-hydroxy-camptothecin (SN-38) lactone and carboxylate in human and rat microsomes and recombinant UDP-glucuronosyltransferase isoforms.
    Tallman MN; Ritter JK; Smith PC
    Drug Metab Dispos; 2005 Jul; 33(7):977-83. PubMed ID: 15833930
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Close association of UGT1A9 IVS1+399C>T with UGT1A1*28, *6, or *60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese.
    Saito Y; Sai K; Maekawa K; Kaniwa N; Shirao K; Hamaguchi T; Yamamoto N; Kunitoh H; Ohe Y; Yamada Y; Tamura T; Yoshida T; Minami H; Ohtsu A; Matsumura Y; Saijo N; Sawada J
    Drug Metab Dispos; 2009 Feb; 37(2):272-6. PubMed ID: 18981166
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.