107 related articles for article (PubMed ID: 11701008)
1. Total syntheses of conformationally constrained didemnin B analogues. replacements of N,O-dimethyltyrosine with L-1,2,3,4-tetrahydroisoquinoline and L-1,2,3,4-tetrahydro-7-methoxyisoquinoline.
Tarver JE; Pfizenmayer AJ; Joullié MM
J Org Chem; 2001 Nov; 66(23):7575-87. PubMed ID: 11701008
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological activity of [Tic5] didemnin B.
Pfizenmayer AJ; Vera MD; Ding X; Xiao D; Chen WC; Joullié MM
Bioorg Med Chem Lett; 1998 Dec; 8(24):3653-6. PubMed ID: 9934489
[TBL] [Abstract][Full Text] [Related]
3. Structure--activity relationships of side-chain modified didemnins.
Ding X; Vera MD; Liang B; Zhao Y; Leonard MS; Joullié MM
Bioorg Med Chem Lett; 2001 Jan; 11(2):231-4. PubMed ID: 11206466
[TBL] [Abstract][Full Text] [Related]
4. (2S,3R) beta-methyl-2',6'-dimethyltyrosine-L-tetrahydroisoquinoline-3-carboxylic acid [(2S,3R)TMT-L-Tic-OH] is a potent, selective delta-opioid receptor antagonist in mouse brain.
Hosohata K; Varga EV; Alfaro-Lopez J; Tang X; Vanderah TW; Porreca F; Hruby VJ; Roeske WR; Yamamura HI
J Pharmacol Exp Ther; 2003 Feb; 304(2):683-8. PubMed ID: 12538822
[TBL] [Abstract][Full Text] [Related]
5. Total synthesis of a conformationally constrained didemnin B analog.
Xiao D; Vera MD; Liang B; Joullié MM
J Org Chem; 2001 Apr; 66(8):2734-42. PubMed ID: 11304195
[TBL] [Abstract][Full Text] [Related]
6. Constrained phenylalanine analogues. Preferred conformation of the 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) residue.
Valle G; Kazmierski WM; Crisma M; Bonora GM; Toniolo C; Hruby VJ
Int J Pept Protein Res; 1992; 40(3-4):222-32. PubMed ID: 1335996
[TBL] [Abstract][Full Text] [Related]
7. Total syntheses and biological investigations of tamandarins A and B and tamandarin A analogs.
Liang B; Richard DJ; Portonovo PS; Joullié MM
J Am Chem Soc; 2001 May; 123(19):4469-74. PubMed ID: 11457232
[TBL] [Abstract][Full Text] [Related]
8. An exploration of the effects of L- and D-tetrahydroisoquinoline-3-carboxylic acid substitutions at positions 2, 3 and 7 in cyclic and linear antagonists of vasopressin and oxytocin and at position 3 in arginine vasopressin.
Manning M; Cheng LL; Stoev S; Bankowski K; Przybyiski J; Klis WA; Sawyer WH; Wo NC; Chan WY
J Pept Sci; 1995; 1(1):66-79. PubMed ID: 9222985
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and cytostatic activities of didemnin derivatives.
Schmidt U; Griesser H; Haas G; Kroner M; Riedl B; Schumacher A; Sutoris F; Haupt A; Emling F
J Pept Res; 1999 Aug; 54(2):146-61. PubMed ID: 10461749
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of didemnin photoaffinity analogues.
Vera MD; Pfizenmayer AJ; Ding X; Ahuja D; Toogood PL; Joullié MM
Bioorg Med Chem Lett; 2001 Jul; 11(14):1871-4. PubMed ID: 11459650
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, biological activity and molecular modeling studies of 1,2,3,4-tetrahydroisoquinoline derivatives as conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor containing a tyrosine moiety.
Baraldi PG; Makaeva R; Pavani MG; Nuñez Mdel C; Spalluto G; Moro S; Falzoni S; Di Virgilio F; Romagnoli R
Arzneimittelforschung; 2002; 52(4):273-85. PubMed ID: 12040970
[TBL] [Abstract][Full Text] [Related]
12. Crystal and molecular structure of didemnin A, an antiviral depsipeptide.
Hossain MB; Van Der Helm D; Antel J; Sheldrick GM; Weinheimer AJ; Sanduja SK
Int J Pept Protein Res; 1996; 47(1-2):20-7. PubMed ID: 8907495
[TBL] [Abstract][Full Text] [Related]
13. Tyrosinium-D-tetrahydroisoquinoline-3-carboxylate 1.5-hydrate and tyrosyl-D-tetrahydroisoquinoline-3-carboxamide hydrate.
Deschamps JR; Flippen-Anderson JL; Moore C; Cudney R; George C
Acta Crystallogr C; 1997 Oct; 53 ( Pt 10)():1478-82. PubMed ID: 9362554
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of protein synthesis by didemnins: cell potency and SAR.
Ahuja D; Geiger A; Ramanjulu JM; Vera MD; SirDeshpande B; Pfizenmayer A; Abazeed M; Krosky DJ; Beidler D; Joullié MM; Toogood PL
J Med Chem; 2000 Nov; 43(22):4212-8. PubMed ID: 11063617
[TBL] [Abstract][Full Text] [Related]
15. [Lys3]Didemnins as potential affinity ligands.
Vera MD; Pfizenmayer AJ; Ding X; Xiao D; Joullié MM
Bioorg Med Chem Lett; 2001 Jan; 11(1):13-6. PubMed ID: 11140723
[TBL] [Abstract][Full Text] [Related]
16. Solution and solid-state structure of the diketopiperazine of tyrosyl-tetrahydroisoquinoline-3-carboxylic acid.
Ciajolo MR; Balboni G; Picone D; Salvadori S; Tancredi T; Temussi PA; Tuzi A
Int J Pept Protein Res; 1995 Aug; 46(2):134-8. PubMed ID: 8567167
[TBL] [Abstract][Full Text] [Related]
17. Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.
Mohler ML; Kang GS; Hong SS; Patil R; Kirichenko OV; Li W; Rakov IM; Geisert EE; Miller DD
J Med Chem; 2006 Sep; 49(19):5845-8. PubMed ID: 16970409
[TBL] [Abstract][Full Text] [Related]
18. Development of a model for the delta opioid receptor pharmacophore. 1. Conformationally restricted Tyr1 replacements in the cyclic delta receptor selective tetrapeptide Tyr-c[D-Cys-Phe-D-Pen]OH (JOM-13).
Mosberg HI; Lomize AL; Wang C; Kroona H; Heyl DL; Sobczyk-Kojiro K; Ma W; Mousigian C; Porreca F
J Med Chem; 1994 Dec; 37(25):4371-83. PubMed ID: 7996549
[TBL] [Abstract][Full Text] [Related]
19. Crystal structures of dipeptides containing the Dmt-Tic pharmacophore.
Bryant SD; George C; Flippen-Anderson JL; Deschamps JR; Salvadori S; Balboni G; Guerrini R; Lazarus LH
J Med Chem; 2002 Dec; 45(25):5506-13. PubMed ID: 12459018
[TBL] [Abstract][Full Text] [Related]
20. Conformational analysis of potent and very selective delta opioid dipeptide antagonists.
Amodeo P; Balboni G; Crescenzi O; Guerrini R; Picone D; Salvadori S; Tancredi T; Temussi PA
FEBS Lett; 1995 Dec; 377(3):363-7. PubMed ID: 8549756
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]