92 related articles for article (PubMed ID: 11705857)
1. Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers.
Whetstine JR; Gifford AJ; Witt T; Liu XY; Flatley RM; Norris M; Haber M; Taub JW; Ravindranath Y; Matherly LH
Clin Cancer Res; 2001 Nov; 7(11):3416-22. PubMed ID: 11705857
[TBL] [Abstract][Full Text] [Related]
2. Primary acute lymphoblastic leukemia cells use a novel promoter and 5'noncoding exon for the human reduced folate carrier that encodes a modified carrier translated from an upstream translational start.
Flatley RM; Payton SG; Taub JW; Matherly LH
Clin Cancer Res; 2004 Aug; 10(15):5111-22. PubMed ID: 15297414
[TBL] [Abstract][Full Text] [Related]
3. Transcriptional regulation of the human reduced folate carrier in childhood acute lymphoblastic leukemia cells.
Liu M; Ge Y; Payton SG; Aboukameel A; Buck S; Flatley RM; Haska C; Mohammad R; Taub JW; Matherly LH
Clin Cancer Res; 2006 Jan; 12(2):608-16. PubMed ID: 16428507
[TBL] [Abstract][Full Text] [Related]
4. Restoration of high-level transport activity by human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier function.
Liu XY; Witt TL; Matherly LH
Biochem J; 2003 Jan; 369(Pt 1):31-7. PubMed ID: 12227830
[TBL] [Abstract][Full Text] [Related]
5. Functional interactions between arginine-133 and aspartate-88 in the human reduced folate carrier: evidence for a charge-pair association.
Liu XY; Matherly LH
Biochem J; 2001 Sep; 358(Pt 2):511-6. PubMed ID: 11513752
[TBL] [Abstract][Full Text] [Related]
6. Identification of lysine-411 in the human reduced folate carrier as an important determinant of substrate selectivity and carrier function by systematic site-directed mutagenesis.
Witt TL; Matherly LH
Biochim Biophys Acta; 2002 Dec; 1567(1-2):56-62. PubMed ID: 12488038
[TBL] [Abstract][Full Text] [Related]
7. Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: relationship to immunophenotype and ploidy.
Zhang L; Taub JW; Williamson M; Wong SC; Hukku B; Pullen J; Ravindranath Y; Matherly LH
Clin Cancer Res; 1998 Sep; 4(9):2169-77. PubMed ID: 9748136
[TBL] [Abstract][Full Text] [Related]
8. Role of the E45K-reduced folate carrier gene mutation in methotrexate resistance in human leukemia cells.
Gifford AJ; Haber M; Witt TL; Whetstine JR; Taub JW; Matherly LH; Norris MD
Leukemia; 2002 Dec; 16(12):2379-87. PubMed ID: 12454742
[TBL] [Abstract][Full Text] [Related]
9. Reduced folate carrier mutations are not the mechanism underlying methotrexate resistance in childhood acute lymphoblastic leukemia.
Kaufman Y; Drori S; Cole PD; Kamen BA; Sirota J; Ifergan I; Arush MW; Elhasid R; Sahar D; Kaspers GJ; Jansen G; Matherly LH; Rechavi G; Toren A; Assaraf YG
Cancer; 2004 Feb; 100(4):773-82. PubMed ID: 14770434
[TBL] [Abstract][Full Text] [Related]
10. Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity.
Wong SC; McQuade R; Proefke SA; Bhushan A; Matherly LH
Biochem Pharmacol; 1997 Jan; 53(2):199-206. PubMed ID: 9037252
[TBL] [Abstract][Full Text] [Related]
11. Characterization of a human alternatively spliced truncated reduced folate carrier increasing folate accumulation in parental leukemia cells.
Drori S; Sprecher H; Shemer G; Jansen G; Goldman ID; Assaraf YG
Eur J Biochem; 2000 Feb; 267(3):690-702. PubMed ID: 10651805
[TBL] [Abstract][Full Text] [Related]
12. Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells.
Wong SC; Proefke SA; Bhushan A; Matherly LH
J Biol Chem; 1995 Jul; 270(29):17468-75. PubMed ID: 7615551
[TBL] [Abstract][Full Text] [Related]
13. Sequence alterations in the reduced folate carrier are observed in osteosarcoma tumor samples.
Yang R; Sowers R; Mazza B; Healey JH; Huvos A; Grier H; Bernstein M; Beardsley GP; Krailo MD; Devidas M; Bertino JR; Meyers PA; Gorlick R
Clin Cancer Res; 2003 Feb; 9(2):837-44. PubMed ID: 12576457
[TBL] [Abstract][Full Text] [Related]
14. The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoter.
Whetstine JR; Flatley RM; Matherly LH
Biochem J; 2002 Nov; 367(Pt 3):629-40. PubMed ID: 12144527
[TBL] [Abstract][Full Text] [Related]
15. Repression of human reduced folate carrier gene expression by wild type p53.
Ding BC; Whetstine JR; Witt TL; Schuetz JD; Matherly LH
J Biol Chem; 2001 Mar; 276(12):8713-9. PubMed ID: 11106643
[TBL] [Abstract][Full Text] [Related]
16. Prognostic role of the reduced folate carrier, the major membrane transporter for methotrexate, in childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.
Ge Y; Haska CL; LaFiura K; Devidas M; Linda SB; Liu M; Thomas R; Taub JW; Matherly LH
Clin Cancer Res; 2007 Jan; 13(2 Pt 1):451-7. PubMed ID: 17255265
[TBL] [Abstract][Full Text] [Related]
17. Characterization of a cysteine-less human reduced folate carrier: localization of a substrate-binding domain by cysteine-scanning mutagenesis and cysteine accessibility methods.
Cao W; Matherly LH
Biochem J; 2003 Aug; 374(Pt 1):27-36. PubMed ID: 12749765
[TBL] [Abstract][Full Text] [Related]
18. Effects of 5' untranslated region diversity on the posttranscriptional regulation of the human reduced folate carrier.
Payton SG; Haska CL; Flatley RM; Ge Y; Matherly LH
Biochim Biophys Acta; 2007 Feb; 1769(2):131-8. PubMed ID: 17306382
[TBL] [Abstract][Full Text] [Related]
19. Sensitivity to 5,10-dideazatetrahydrofolate is fully conserved in a murine leukemia cell line highly resistant to methotrexate due to impaired transport mediated by the reduced folate carrier.
Zhao R; Gao F; Babani S; Goldman ID
Clin Cancer Res; 2000 Aug; 6(8):3304-11. PubMed ID: 10955817
[TBL] [Abstract][Full Text] [Related]
20. Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods.
Hou Z; Stapels SE; Haska CL; Matherly LH
J Biol Chem; 2005 Oct; 280(43):36206-13. PubMed ID: 16115875
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
