These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 11706404)

  • 1. The role of genetic abnormalities of PTEN and the phosphatidylinositol 3-kinase pathway in breast and ovarian tumorigenesis, prognosis, and therapy.
    Mills GB; Lu Y; Fang X; Wang H; Eder A; Mao M; Swaby R; Cheng KW; Stokoe D; Siminovitch K; Jaffe R; Gray J
    Semin Oncol; 2001 Oct; 28(5 Suppl 16):125-41. PubMed ID: 11706404
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells.
    Lu Y; Lin YZ; LaPushin R; Cuevas B; Fang X; Yu SX; Davies MA; Khan H; Furui T; Mao M; Zinner R; Hung MC; Steck P; Siminovitch K; Mills GB
    Oncogene; 1999 Nov; 18(50):7034-45. PubMed ID: 10597304
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
    Ramaswamy S; Nakamura N; Vazquez F; Batt DB; Perera S; Roberts TM; Sellers WR
    Proc Natl Acad Sci U S A; 1999 Mar; 96(5):2110-5. PubMed ID: 10051603
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The biology and clinical relevance of the PTEN tumor suppressor pathway.
    Sansal I; Sellers WR
    J Clin Oncol; 2004 Jul; 22(14):2954-63. PubMed ID: 15254063
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.
    Weng LP; Smith WM; Dahia PL; Ziebold U; Gil E; Lees JA; Eng C
    Cancer Res; 1999 Nov; 59(22):5808-14. PubMed ID: 10582703
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway.
    Zhang J; Choi Y; Mavromatis B; Lichtenstein A; Li W
    Oncogene; 2003 Sep; 22(40):6289-95. PubMed ID: 13679867
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pten signaling in gliomas.
    Knobbe CB; Merlo A; Reifenberger G
    Neuro Oncol; 2002 Jul; 4(3):196-211. PubMed ID: 12084351
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PTEN expression causes feedback upregulation of insulin receptor substrate 2.
    Simpson L; Li J; Liaw D; Hennessy I; Oliner J; Christians F; Parsons R
    Mol Cell Biol; 2001 Jun; 21(12):3947-58. PubMed ID: 11359902
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway.
    Kim S; Domon-Dell C; Wang Q; Chung DH; Di Cristofano A; Pandolfi PP; Freund JN; Evers BM
    Gastroenterology; 2002 Oct; 123(4):1163-78. PubMed ID: 12360479
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Growth suppression of human ovarian cancer cells by adenovirus-mediated transfer of the PTEN gene.
    Minaguchi T; Mori T; Kanamori Y; Matsushima M; Yoshikawa H; Taketani Y; Nakamura Y
    Cancer Res; 1999 Dec; 59(24):6063-7. PubMed ID: 10626791
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma.
    Saal LH; Holm K; Maurer M; Memeo L; Su T; Wang X; Yu JS; Malmström PO; Mansukhani M; Enoksson J; Hibshoosh H; Borg A; Parsons R
    Cancer Res; 2005 Apr; 65(7):2554-9. PubMed ID: 15805248
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of mutation and expression of PTEN gene mRNA on tumorigenesis and progression of epithelial ovarian cancer.
    Chen Y; Zheng H; Yang X; Sun L; Xin Y
    Chin Med Sci J; 2004 Mar; 19(1):25-30. PubMed ID: 15104221
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells.
    Choi Y; Zhang J; Murga C; Yu H; Koller E; Monia BP; Gutkind JS; Li W
    Oncogene; 2002 Aug; 21(34):5289-300. PubMed ID: 12149650
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
    Zhong H; Chiles K; Feldser D; Laughner E; Hanrahan C; Georgescu MM; Simons JW; Semenza GL
    Cancer Res; 2000 Mar; 60(6):1541-5. PubMed ID: 10749120
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3'-kinase/Akt pathway signaling.
    She QB; Solit D; Basso A; Moasser MM
    Clin Cancer Res; 2003 Oct; 9(12):4340-6. PubMed ID: 14555504
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PTEN: life as a tumor suppressor.
    Simpson L; Parsons R
    Exp Cell Res; 2001 Mar; 264(1):29-41. PubMed ID: 11237521
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
    She QB; Gruvberger-Saal SK; Maurer M; Chen Y; Jumppanen M; Su T; Dendy M; Lau YK; Memeo L; Horlings HM; van de Vijver MJ; Isola J; Hibshoosh H; Rosen N; Parsons R; Saal LH
    BMC Cancer; 2016 Aug; 16():587. PubMed ID: 27484095
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene.
    Li J; Simpson L; Takahashi M; Miliaresis C; Myers MP; Tonks N; Parsons R
    Cancer Res; 1998 Dec; 58(24):5667-72. PubMed ID: 9865719
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.
    Paramio JM; Navarro M; Segrelles C; Gómez-Casero E; Jorcano JL
    Oncogene; 1999 Dec; 18(52):7462-8. PubMed ID: 10602505
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.