BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

369 related articles for article (PubMed ID: 11710708)

  • 1. The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients.
    van Ede AE; Laan RF; Blom HJ; Huizinga TW; Haagsma CJ; Giesendorf BA; de Boo TM; van de Putte LB
    Arthritis Rheum; 2001 Nov; 44(11):2525-30. PubMed ID: 11710708
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Homocysteine and folate status in methotrexate-treated patients with rheumatoid arthritis.
    van Ede AE; Laan RF; Blom HJ; Boers GH; Haagsma CJ; Thomas CM; De Boo TM; van de Putte LB
    Rheumatology (Oxford); 2002 Jun; 41(6):658-65. PubMed ID: 12048292
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses.
    Urano W; Taniguchi A; Yamanaka H; Tanaka E; Nakajima H; Matsuda Y; Akama H; Kitamura Y; Kamatani N
    Pharmacogenetics; 2002 Apr; 12(3):183-90. PubMed ID: 11927833
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Correlation between methotrexate efficacy & toxicity with C677T polymorphism of the methylenetetrahydrofolate gene in rheumatoid arthritis patients on folate supplementation.
    Aggarwal P; Naik S; Mishra KP; Aggarwal A; Misra R
    Indian J Med Res; 2006 Nov; 124(5):521-6. PubMed ID: 17213520
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Influence of sulphasalazine, methotrexate, and the combination of both on plasma homocysteine concentrations in patients with rheumatoid arthritis.
    Haagsma CJ; Blom HJ; van Riel PL; van't Hof MA; Giesendorf BA; van Oppenraaij-Emmerzaal D; van de Putte LB
    Ann Rheum Dis; 1999 Feb; 58(2):79-84. PubMed ID: 10343521
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study.
    van Ede AE; Laan RF; Rood MJ; Huizinga TW; van de Laar MA; van Denderen CJ; Westgeest TA; Romme TC; de Rooij DJ; Jacobs MJ; de Boo TM; van der Wilt GJ; Severens JL; Hartman M; Krabbe PF; Dijkmans BA; Breedveld FC; van de Putte LB
    Arthritis Rheum; 2001 Jul; 44(7):1515-24. PubMed ID: 11465701
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.
    Wessels JA; de Vries-Bouwstra JK; Heijmans BT; Slagboom PE; Goekoop-Ruiterman YP; Allaart CF; Kerstens PJ; van Zeben D; Breedveld FC; Dijkmans BA; Huizinga TW; Guchelaar HJ
    Arthritis Rheum; 2006 Apr; 54(4):1087-95. PubMed ID: 16572443
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Influence of MTHFR C677T polymorphism on methotrexate monotherapy discontinuation in rheumatoid arthritis patients: results from the GAPAID European project.
    Uribarri M; Ruiz-Larrañaga O; Arteta D; Hernández L; Alcaro MC; Martínez A; Escorza-Treviño S; Estonba A; Migliorini P; Czirják L; del Amo J
    Clin Exp Rheumatol; 2015; 33(5):699-705. PubMed ID: 26314492
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The C677T polymorphism in the MTHFR gene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population.
    Cáliz R; del Amo J; Balsa A; Blanco F; Silva L; Sanmarti R; Martínez FG; Collado MD; Ramirez Mdel C; Tejedor D; Artieda M; Pascual-Salcedo D; Oreiro N; Andreu JL; Graell E; Simon L; Martínez A; Mulero J
    Scand J Rheumatol; 2012 Feb; 41(1):10-4. PubMed ID: 22044028
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Association Between MTHFR C677T Polymorphism and Methotrexate Treatment Outcome in Rheumatoid Arthritis Patients: A Systematic Review and Meta-Analysis.
    Shao W; Yuan Y; Li Y
    Genet Test Mol Biomarkers; 2017 May; 21(5):275-285. PubMed ID: 28277784
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differing effects of methylenetetrahydrofolate reductase single nucleotide polymorphisms on methotrexate efficacy and toxicity in rheumatoid arthritis.
    Evans WE
    Pharmacogenetics; 2002 Apr; 12(3):181-2. PubMed ID: 11927832
    [No Abstract]   [Full Text] [Related]  

  • 12. Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis.
    Shea B; Swinden MV; Tanjong Ghogomu E; Ortiz Z; Katchamart W; Rader T; Bombardier C; Wells GA; Tugwell P
    Cochrane Database Syst Rev; 2013 May; 2013(5):CD000951. PubMed ID: 23728635
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genetic Determinants of Methotrexate Toxicity in Tunisian Patients with Rheumatoid Arthritis: A Study of Polymorphisms Involved in the MTX Metabolic Pathway.
    Chaabane S; Marzouk S; Akrout R; Ben Hamad M; Achour Y; Rebai A; Keskes L; Fourati H; Bahloul Z; Maalej A
    Eur J Drug Metab Pharmacokinet; 2016 Aug; 41(4):385-93. PubMed ID: 26077125
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Methylenetetrahydrofolate reductase polymorphisms and methotrexate: no association with response to therapy nor with drug-related adverse events in an Italian population of rheumatic patients.
    Taraborelli M; Andreoli L; Archetti S; Ferrari M; Cattaneo R; Tincani A
    Clin Exp Rheumatol; 2009; 27(3):499-502. PubMed ID: 19604445
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association of hyperhomocysteinemia with genetic variants in key enzymes of homocysteine metabolism and methotrexate toxicity in rheumatoid arthritis patients.
    Chaabane S; Messedi M; Akrout R; Ben Hamad M; Turki M; Marzouk S; Keskes L; Bahloul Z; Rebai A; Ayedi F; Maalej A
    Inflamm Res; 2018 Aug; 67(8):703-710. PubMed ID: 29796841
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis.
    Kumagai K; Hiyama K; Oyama T; Maeda H; Kohno N
    Int J Mol Med; 2003 May; 11(5):593-600. PubMed ID: 12684695
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacogenetic polymorphisms contributing to toxicity induced by methotrexate in the southern Spanish population with rheumatoid arthritis.
    Plaza-Plaza JC; Aguilera M; Cañadas-Garre M; Chemello C; González-Utrilla A; Faus Dader MJ; Calleja MA
    OMICS; 2012 Nov; 16(11):589-95. PubMed ID: 23095111
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cost-effectiveness analysis of MTHFR polymorphism screening by polymerase chain reaction in Korean patients with rheumatoid arthritis receiving methotrexate.
    Kim SK; Jun JB; El-Sohemy A; Bae SC
    J Rheumatol; 2006 Jul; 33(7):1266-74. PubMed ID: 16758511
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The impact of C677T and A1298C MTHFR polymorphisms on methotrexate therapeutic response in East Bohemian region rheumatoid arthritis patients.
    Soukup T; Dosedel M; Pavek P; Nekvindova J; Barvik I; Bubancova I; Bradna P; Kubena AA; Carazo AF; Veleta T; Vlcek J
    Rheumatol Int; 2015 Jul; 35(7):1149-61. PubMed ID: 25618758
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Polymorphisms C677T and A1298C in the MTHFR gene in Mexican patients with rheumatoid arthritis treated with methotrexate: implication with elevation of transaminases.
    Mena JP; Salazar-Páramo M; González-López L; Gámez-Nava JI; Sandoval-Ramirez L; Sánchez JD; Figuera LE; Muñoz-Valle FJ; Vazquez del Mercado M; Dávalos IP
    Pharmacogenomics J; 2011 Aug; 11(4):287-91. PubMed ID: 20514079
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.