BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 11714603)

  • 1. Synthesis of antitumor dendritic imides.
    Braña MF; Domínguez G; Sáez B; Romerdahl C; Robinson S; Barlozzari T
    Bioorg Med Chem Lett; 2001 Dec; 11(23):3027-9. PubMed ID: 11714603
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and antitumour activity of new dendritic polyamines-(imide-DNA-intercalator) conjugates: potent Lck inhibitors.
    Braña MF; Domínguez G; Sáez B; Romerdahl C; Robinson S; Barlozzari T
    Eur J Med Chem; 2002 Jul; 37(7):541-51. PubMed ID: 12126773
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular design, synthesis, and structure-Activity relationships leading to the potent and selective p56(lck) inhibitor BMS-243117.
    Das J; Lin J; Moquin RV; Shen Z; Spergel SH; Wityak J; Doweyko AM; DeFex HF; Fang Q; Pang S; Pitt S; Shen DR; Schieven GL; Barrish JC
    Bioorg Med Chem Lett; 2003 Jul; 13(13):2145-9. PubMed ID: 12798323
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antiproliferative effect of synthetic cyclic imides (methylphtalimides, carboxylic acid phtalimides and itaconimides) against human cancer cell lines.
    Stiz D; Campos A; Lúcia Tasca Gois Ruiz A; Ernesto de Carvalho J; Corrêa R; Cechinel-Filho V
    Z Naturforsch C J Biosci; 2016 Nov; 71(11-12):423-427. PubMed ID: 27768587
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and SAR of novel imidazoquinoxaline-based Lck inhibitors: improvement of cell potency.
    Chen P; Iwanowicz EJ; Norris D; Gu HH; Lin J; Moquin RV; Das J; Wityak J; Spergel SH; de Fex H; Pang S; Pitt S; Shen DR; Schieven GL; Barrish JC
    Bioorg Med Chem Lett; 2002 Nov; 12(21):3153-6. PubMed ID: 12372522
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56(lck) inhibitors.
    Das J; Moquin RV; Lin J; Liu C; Doweyko AM; DeFex HF; Fang Q; Pang S; Pitt S; Shen DR; Schieven GL; Barrish JC; Wityak J
    Bioorg Med Chem Lett; 2003 Aug; 13(15):2587-90. PubMed ID: 12852972
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of non-phosphate-containing small molecular weight inhibitors of the tyrosine kinase p56 Lck SH2 domain via in silico screening against the pY + 3 binding site.
    Huang N; Nagarsekar A; Xia G; Hayashi J; MacKerell AD
    J Med Chem; 2004 Jul; 47(14):3502-11. PubMed ID: 15214778
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The development of novel 1,2-dihydro-pyrimido[4,5-c]pyridazine based inhibitors of lymphocyte specific kinase (Lck).
    Sabat M; Vanrens JC; Brugel TA; Maier J; Laufersweiler MJ; Golebiowski A; De B; Easwaran V; Hsieh LC; Rosegen J; Berberich S; Suchanek E; Janusz MJ
    Bioorg Med Chem Lett; 2006 Aug; 16(16):4257-61. PubMed ID: 16757169
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SVM model for virtual screening of Lck inhibitors.
    Liew CY; Ma XH; Liu X; Yap CW
    J Chem Inf Model; 2009 Apr; 49(4):877-85. PubMed ID: 19267483
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, and biological evaluation of substituted naphthalene imides and diimides as anticancer agent.
    Tumiatti V; Milelli A; Minarini A; Micco M; Gasperi Campani A; Roncuzzi L; Baiocchi D; Marinello J; Capranico G; Zini M; Stefanelli C; Melchiorre C
    J Med Chem; 2009 Dec; 52(23):7873-7. PubMed ID: 19954251
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and anticancer activity of 5'-phthaloylnucleosides.
    Orzeszko A; Vilpo J; Vilpo L; Kamińska B
    Pharmazie; 2003 Mar; 58(3):169-72. PubMed ID: 12685810
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck -- a selectivity insight.
    Burchat AF; Calderwood DJ; Friedman MM; Hirst GC; Li B; Rafferty P; Ritter K; Skinner BS
    Bioorg Med Chem Lett; 2002 Jun; 12(12):1687-90. PubMed ID: 12039591
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56(Lck).
    Wityak J; Das J; Moquin RV; Shen Z; Lin J; Chen P; Doweyko AM; Pitt S; Pang S; Shen DR; Fang Q; de Fex HF; Schieven GL; Kanner SB; Barrish JC
    Bioorg Med Chem Lett; 2003 Nov; 13(22):4007-10. PubMed ID: 14592495
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of chalcone-imide derivatives and investigation of their anticancer and antimicrobial activities, carbonic anhydrase and acetylcholinesterase enzymes inhibition profiles.
    Kocyigit UM; Budak Y; Gürdere MB; Ertürk F; Yencilek B; Taslimi P; Gülçin İ; Ceylan M
    Arch Physiol Biochem; 2018 Feb; 124(1):61-68. PubMed ID: 28792233
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of p56(lck) tyrosine kinase by isothiazolones.
    Trevillyan JM; Chiou XG; Ballaron SJ; Tang QM; Buko A; Sheets MP; Smith ML; Putman CB; Wiedeman P; Tu N; Madar D; Smith HT; Gubbins EJ; Warrior UP; Chen YW; Mollison KW; Faltynek CR; Djurić SW
    Arch Biochem Biophys; 1999 Apr; 364(1):19-29. PubMed ID: 10087161
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and antitumor activity evaluation of maleopimaric acid N-aryl imide atropisomers.
    Yao GY; Ye MY; Huang RZ; Li YJ; Zhu YT; Pan YM; Liao ZX; Wang HS
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6755-8. PubMed ID: 24211021
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tebrophen--an old polyphenol drug with anticancer potential.
    Rubelj I; Stepanić V; Jelić D; Vidaček NŠ; Kalajžić AĆ; Ivanković M; Nujić K; Matijašić M; Verbanac D
    Molecules; 2012 Jun; 17(7):7864-86. PubMed ID: 22743590
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A QSAR study on a series of pyrrole derivatives acting as lymphocyte-specific kinase (Lck) inhibitors.
    Anwer Z; Gupta SP
    Med Chem; 2012 Jul; 8(4):649-55. PubMed ID: 22548340
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, antitumor evaluation and DNA photocleaving activity of novel methylthiazonaphthalimides with aminoalkyl side chains.
    Li Z; Yang Q; Qian X
    Bioorg Med Chem Lett; 2005 Jun; 15(12):3143-6. PubMed ID: 15876532
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pyrrolo[2,3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck I.
    Arnold LD; Calderwood DJ; Dixon RW; Johnston DN; Kamens JS; Munschauer R; Rafferty P; Ratnofsky SE
    Bioorg Med Chem Lett; 2000 Oct; 10(19):2167-70. PubMed ID: 11012021
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.