BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

584 related articles for article (PubMed ID: 11714888)

  • 1. Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms.
    Court MH; Duan SX; von Moltke LL; Greenblatt DJ; Patten CJ; Miners JO; Mackenzie PI
    J Pharmacol Exp Ther; 2001 Dec; 299(3):998-1006. PubMed ID: 11714888
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of niflumic acid as a selective inhibitor of human liver microsomal UDP-glucuronosyltransferase 1A9: application to the reaction phenotyping of acetaminophen glucuronidation.
    Miners JO; Bowalgaha K; Elliot DJ; Baranczewski P; Knights KM
    Drug Metab Dispos; 2011 Apr; 39(4):644-52. PubMed ID: 21245288
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin.
    Hanioka N; Ozawa S; Jinno H; Ando M; Saito Y; Sawada J
    Xenobiotica; 2001 Oct; 31(10):687-99. PubMed ID: 11695848
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
    Ma L; Sun J; Peng Y; Zhang R; Shao F; Hu X; Zhu J; Wang X; Cheng X; Zhu Y; Wan P; Feng D; Wu H; Wang G
    Drug Metab Dispos; 2012 Apr; 40(4):734-41. PubMed ID: 22238289
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glucuronidation of etoposide in human liver microsomes is specifically catalyzed by UDP-glucuronosyltransferase 1A1.
    Watanabe Y; Nakajima M; Ohashi N; Kume T; Yokoi T
    Drug Metab Dispos; 2003 May; 31(5):589-95. PubMed ID: 12695347
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
    Mano Y; Usui T; Kamimura H
    Drug Metab Dispos; 2007 Nov; 35(11):2040-4. PubMed ID: 17670842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Troglitazone glucuronidation in human liver and intestine microsomes: high catalytic activity of UGT1A8 and UGT1A10.
    Watanabe Y; Nakajima M; Yokoi T
    Drug Metab Dispos; 2002 Dec; 30(12):1462-9. PubMed ID: 12433820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol.
    Chen M; LeDuc B; Kerr S; Howe D; Williams DA
    Drug Metab Dispos; 2010 Mar; 38(3):368-75. PubMed ID: 20008037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Involvement of multiple UDP-glucuronosyltransferase 1A isoforms in glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes.
    Nakajima M; Sakata N; Ohashi N; Kume T; Yokoi T
    Drug Metab Dispos; 2002 Nov; 30(11):1250-6. PubMed ID: 12386132
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of N-glucuronidation of 4-(5-pyridin-4-yl-1H-[1,2,4]triazol-3-yl) pyridine-2-carbonitrile (FYX-051): a new xanthine oxidoreductase inhibitor.
    Omura K; Nakazawa T; Sato T; Iwanaga T; Nagata O
    Drug Metab Dispos; 2007 Dec; 35(12):2143-8. PubMed ID: 17761779
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human UDP-glucuronosyltransferase isoforms involved in bisphenol A glucuronidation.
    Hanioka N; Naito T; Narimatsu S
    Chemosphere; 2008 Dec; 74(1):33-6. PubMed ID: 18990428
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kinetics of acetaminophen glucuronidation by UDP-glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential implications in acetaminophen-induced hepatotoxicity.
    Mutlib AE; Goosen TC; Bauman JN; Williams JA; Kulkarni S; Kostrubsky S
    Chem Res Toxicol; 2006 May; 19(5):701-9. PubMed ID: 16696573
    [TBL] [Abstract][Full Text] [Related]  

  • 13. UDP-glucuronosyltransferase 1A6 is the major isozyme responsible for protocatechuic aldehyde glucuronidation in human liver microsomes.
    Liu HX; Liu Y; Zhang JW; Li W; Liu HT; Yang L
    Drug Metab Dispos; 2008 Aug; 36(8):1562-9. PubMed ID: 18474676
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
    Fujiwara R; Nakajima M; Yamanaka H; Katoh M; Yokoi T
    Drug Metab Dispos; 2008 Feb; 36(2):361-7. PubMed ID: 17998297
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
    Kaji H; Kume T
    Drug Metab Dispos; 2005 Mar; 33(3):403-12. PubMed ID: 15608137
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The "albumin effect" and drug glucuronidation: bovine serum albumin and fatty acid-free human serum albumin enhance the glucuronidation of UDP-glucuronosyltransferase (UGT) 1A9 substrates but not UGT1A1 and UGT1A6 activities.
    Rowland A; Knights KM; Mackenzie PI; Miners JO
    Drug Metab Dispos; 2008 Jun; 36(6):1056-62. PubMed ID: 18362158
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of human UDP-glucuronosyltransferase isoform(s) responsible for the glucuronidation of 2-(4-chlorophenyl)- 5-(2-furyl)-4-oxazoleacetic acid (TA-1801A).
    Kaji H; Kume T
    Drug Metab Pharmacokinet; 2005 Jun; 20(3):212-8. PubMed ID: 15988124
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stereoselective glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin by human UDP-glucuronosyltransferase (UGT) 1A1, UGT1A9, and UGT2B15: effects of UGT-UGT interactions.
    Nakajima M; Yamanaka H; Fujiwara R; Katoh M; Yokoi T
    Drug Metab Dispos; 2007 Sep; 35(9):1679-86. PubMed ID: 17576806
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interactions between human UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A enzymes.
    Fujiwara R; Nakajima M; Oda S; Yamanaka H; Ikushiro S; Sakaki T; Yokoi T
    J Pharm Sci; 2010 Jan; 99(1):442-54. PubMed ID: 19475557
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.
    Yamanaka H; Nakajima M; Katoh M; Kanoh A; Tamura O; Ishibashi H; Yokoi T
    Drug Metab Dispos; 2005 Jan; 33(1):23-30. PubMed ID: 15470160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.