These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 11719452)

  • 1. Radiosensitization of p53 mutant cells by PD0166285, a novel G(2) checkpoint abrogator.
    Wang Y; Li J; Booher RN; Kraker A; Lawrence T; Leopold WR; Sun Y
    Cancer Res; 2001 Nov; 61(22):8211-7. PubMed ID: 11719452
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Wild-type TP53 inhibits G(2)-phase checkpoint abrogation and radiosensitization induced by PD0166285, a WEE1 kinase inhibitor.
    Li J; Wang Y; Sun Y; Lawrence TS
    Radiat Res; 2002 Mar; 157(3):322-30. PubMed ID: 11839095
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cell cycle regulation by the Wee1 inhibitor PD0166285, pyrido [2,3-d] pyimidine, in the B16 mouse melanoma cell line.
    Hashimoto O; Shinkawa M; Torimura T; Nakamura T; Selvendiran K; Sakamoto M; Koga H; Ueno T; Sata M
    BMC Cancer; 2006 Dec; 6():292. PubMed ID: 17177986
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Negative regulation of Wee1 expression and Cdc2 phosphorylation during p53-mediated growth arrest and apoptosis.
    Leach SD; Scatena CD; Keefer CJ; Goodman HA; Song SY; Yang L; Pietenpol JA
    Cancer Res; 1998 Aug; 58(15):3231-6. PubMed ID: 9699647
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Cell cycle regulation after exposure to ionizing radiation].
    Teyssier F; Bay JO; Dionet C; Verrelle P
    Bull Cancer; 1999 Apr; 86(4):345-57. PubMed ID: 10341340
    [TBL] [Abstract][Full Text] [Related]  

  • 6. WEE1 inhibition sensitizes osteosarcoma to radiotherapy.
    PosthumaDeBoer J; Würdinger T; Graat HC; van Beusechem VW; Helder MN; van Royen BJ; Kaspers GJ
    BMC Cancer; 2011 Apr; 11():156. PubMed ID: 21529352
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dissociation between cell cycle arrest and apoptosis can occur in Li-Fraumeni cells heterozygous for p53 gene mutations.
    Delia D; Goi K; Mizutani S; Yamada T; Aiello A; Fontanella E; Lamorte G; Iwata S; Ishioka C; Krajewski S; Reed JC; Pierotti MA
    Oncogene; 1997 May; 14(18):2137-47. PubMed ID: 9174049
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Abolishment of the Tyr-15 inhibitory phosphorylation site on cdc2 reduces the radiation-induced G(2) delay, revealing a potential checkpoint in early mitosis.
    Fletcher L; Cheng Y; Muschel RJ
    Cancer Res; 2002 Jan; 62(1):241-50. PubMed ID: 11782384
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
    Hirose Y; Berger MS; Pieper RO
    Cancer Res; 2001 Aug; 61(15):5843-9. PubMed ID: 11479224
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanisms of mitotic cell death induced by chemotherapy-mediated G2 checkpoint abrogation.
    Vogel C; Hager C; Bastians H
    Cancer Res; 2007 Jan; 67(1):339-45. PubMed ID: 17210716
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Potentiation of radiosensitivity by staurosporine associated with abrogation of G2 phase arrest].
    Sun XC; Wang JJ; Zhen YS; Shao RG
    Yao Xue Xue Bao; 2002 Jun; 37(6):419-23. PubMed ID: 12579796
    [TBL] [Abstract][Full Text] [Related]  

  • 12. UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.
    Wang Q; Fan S; Eastman A; Worland PJ; Sausville EA; O'Connor PM
    J Natl Cancer Inst; 1996 Jul; 88(14):956-65. PubMed ID: 8667426
    [TBL] [Abstract][Full Text] [Related]  

  • 13. G2 arrest in response to topoisomerase II inhibitors: the role of p53.
    Clifford B; Beljin M; Stark GR; Taylor WR
    Cancer Res; 2003 Jul; 63(14):4074-81. PubMed ID: 12874009
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells.
    Poon RY; Chau MS; Yamashita K; Hunter T
    Cancer Res; 1997 Nov; 57(22):5168-78. PubMed ID: 9371520
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p53 regulates Cdc2 independently of inhibitory phosphorylation to reinforce radiation-induced G2 arrest in human cells.
    Winters ZE; Ongkeko WM; Harris AL; Norbury CJ
    Oncogene; 1998 Aug; 17(6):673-84. PubMed ID: 9715268
    [TBL] [Abstract][Full Text] [Related]  

  • 16. WEE1 kinase targeting combined with DNA-damaging cancer therapy catalyzes mitotic catastrophe.
    De Witt Hamer PC; Mir SE; Noske D; Van Noorden CJ; Würdinger T
    Clin Cancer Res; 2011 Jul; 17(13):4200-7. PubMed ID: 21562035
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
    Castedo M; Perfettini JL; Roumier T; Yakushijin K; Horne D; Medema R; Kroemer G
    Oncogene; 2004 May; 23(25):4353-61. PubMed ID: 15048074
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of proteasome-dependent degradation of Wee1 in G2-arrested Hep3B cells by TGF beta 1.
    Hashimoto O; Ueno T; Kimura R; Ohtsubo M; Nakamura T; Koga H; Torimura T; Uchida S; Yamashita K; Sata M
    Mol Carcinog; 2003 Apr; 36(4):171-82. PubMed ID: 12669309
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential sensitivity of p53(-) and p53(+) cells to caffeine-induced radiosensitization and override of G2 delay.
    Powell SN; DeFrank JS; Connell P; Eogan M; Preffer F; Dombkowski D; Tang W; Friend S
    Cancer Res; 1995 Apr; 55(8):1643-8. PubMed ID: 7712468
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25.
    Elder RT; Yu M; Chen M; Zhu X; Yanagida M; Zhao Y
    Virology; 2001 Sep; 287(2):359-70. PubMed ID: 11531413
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.