325 related articles for article (PubMed ID: 11719502)
1. p21-activated kinase links Rac/Cdc42 signaling to merlin.
Xiao GH; Beeser A; Chernoff J; Testa JR
J Biol Chem; 2002 Jan; 277(2):883-6. PubMed ID: 11719502
[TBL] [Abstract][Full Text] [Related]
2. The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.
Shaw RJ; Paez JG; Curto M; Yaktine A; Pruitt WM; Saotome I; O'Bryan JP; Gupta V; Ratner N; Der CJ; Jacks T; McClatchey AI
Dev Cell; 2001 Jul; 1(1):63-72. PubMed ID: 11703924
[TBL] [Abstract][Full Text] [Related]
3. Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization.
Kissil JL; Johnson KC; Eckman MS; Jacks T
J Biol Chem; 2002 Mar; 277(12):10394-9. PubMed ID: 11782491
[TBL] [Abstract][Full Text] [Related]
4. Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization.
Alfthan K; Heiska L; Grönholm M; Renkema GH; Carpén O
J Biol Chem; 2004 Apr; 279(18):18559-66. PubMed ID: 14981079
[TBL] [Abstract][Full Text] [Related]
5. Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1.
Kissil JL; Wilker EW; Johnson KC; Eckman MS; Yaffe MB; Jacks T
Mol Cell; 2003 Oct; 12(4):841-9. PubMed ID: 14580336
[TBL] [Abstract][Full Text] [Related]
6. Serine 518 phosphorylation modulates merlin intramolecular association and binding to critical effectors important for NF2 growth suppression.
Rong R; Surace EI; Haipek CA; Gutmann DH; Ye K
Oncogene; 2004 Nov; 23(52):8447-54. PubMed ID: 15378014
[TBL] [Abstract][Full Text] [Related]
7. Phosphorylation of the NF2 tumor suppressor in Schwann cells is mediated by Cdc42-Pak and requires paxillin binding.
Thaxton C; Lopera J; Bott M; Baldwin ME; Kalidas P; Fernandez-Valle C
Mol Cell Neurosci; 2007 Feb; 34(2):231-42. PubMed ID: 17175165
[TBL] [Abstract][Full Text] [Related]
8. Erbin and the NF2 tumor suppressor Merlin cooperatively regulate cell-type-specific activation of PAK2 by TGF-beta.
Wilkes MC; Repellin CE; Hong M; Bracamonte M; Penheiter SG; Borg JP; Leof EB
Dev Cell; 2009 Mar; 16(3):433-44. PubMed ID: 19289088
[TBL] [Abstract][Full Text] [Related]
9. Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac.
Morrison H; Sperka T; Manent J; Giovannini M; Ponta H; Herrlich P
Cancer Res; 2007 Jan; 67(2):520-7. PubMed ID: 17234759
[TBL] [Abstract][Full Text] [Related]
10. NF2: the wizardry of merlin.
Xiao GH; Chernoff J; Testa JR
Genes Chromosomes Cancer; 2003 Dec; 38(4):389-99. PubMed ID: 14566860
[TBL] [Abstract][Full Text] [Related]
11. Merlin, a regulator of Hippo signaling, regulates Wnt/β-catenin signaling.
Kim S; Jho EH
BMB Rep; 2016 Jul; 49(7):357-8. PubMed ID: 27345717
[TBL] [Abstract][Full Text] [Related]
12. The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression.
Xiao GH; Gallagher R; Shetler J; Skele K; Altomare DA; Pestell RG; Jhanwar S; Testa JR
Mol Cell Biol; 2005 Mar; 25(6):2384-94. PubMed ID: 15743831
[TBL] [Abstract][Full Text] [Related]
13. VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation.
Huang J; Chen J
Oncogene; 2008 Jul; 27(29):4056-64. PubMed ID: 18332868
[TBL] [Abstract][Full Text] [Related]
14. A clue to the therapy of neurofibromatosis type 2: NF2/merlin is a PAK1 inhibitor.
Hirokawa Y; Tikoo A; Huynh J; Utermark T; Hanemann CO; Giovannini M; Xiao GH; Testa JR; Wood J; Maruta H
Cancer J; 2004; 10(1):20-6. PubMed ID: 15000491
[TBL] [Abstract][Full Text] [Related]
15. β1 integrin-dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin.
Sabra H; Brunner M; Mandati V; Wehrle-Haller B; Lallemand D; Ribba AS; Chevalier G; Guardiola P; Block MR; Bouvard D
J Biol Chem; 2017 Nov; 292(47):19179-19197. PubMed ID: 28972170
[TBL] [Abstract][Full Text] [Related]
16. NF2/Merlin Inactivation and Potential Therapeutic Targets in Mesothelioma.
Sato T; Sekido Y
Int J Mol Sci; 2018 Mar; 19(4):. PubMed ID: 29587439
[TBL] [Abstract][Full Text] [Related]
17. Protein kinase A-mediated phosphorylation of the NF2 tumor suppressor protein merlin at serine 10 affects the actin cytoskeleton.
Laulajainen M; Muranen T; Carpén O; Grönholm M
Oncogene; 2008 May; 27(23):3233-43. PubMed ID: 18071304
[TBL] [Abstract][Full Text] [Related]
18. Inactivation of the NF2 tumor suppressor protein merlin in DU145 prostate cancer cells.
Horiguchi A; Zheng R; Shen R; Nanus DM
Prostate; 2008 Jun; 68(9):975-84. PubMed ID: 18361411
[TBL] [Abstract][Full Text] [Related]
19. p21-Activated kinases are required for transformation in a cell-based model of neurofibromatosis type 2.
Chow HY; Stepanova D; Koch J; Chernoff J
PLoS One; 2010 Nov; 5(11):e13791. PubMed ID: 21072183
[TBL] [Abstract][Full Text] [Related]
20. LIM domain kinases as potential therapeutic targets for neurofibromatosis type 2.
Petrilli A; Copik A; Posadas M; Chang LS; Welling DB; Giovannini M; Fernández-Valle C
Oncogene; 2014 Jul; 33(27):3571-82. PubMed ID: 23934191
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
