These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 11719509)

  • 1. Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen.
    Simon P; Weiss FU; Sahin-Toth M; Parry M; Nayler O; Lenfers B; Schnekenburger J; Mayerle J; Domschke W; Lerch MM
    J Biol Chem; 2002 Feb; 277(7):5404-10. PubMed ID: 11719509
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel cationic trypsinogen (PRSS1) N29T and R122C mutations cause autosomal dominant hereditary pancreatitis.
    Pfützer R; Myers E; Applebaum-Shapiro S; Finch R; Ellis I; Neoptolemos J; Kant JA; Whitcomb DC
    Gut; 2002 Feb; 50(2):271-2. PubMed ID: 11788572
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel A121T mutation in human cationic trypsinogen associated with hereditary pancreatitis: functional data indicating a loss-of-function mutation influencing the R122 trypsin cleavage site.
    Felderbauer P; Schnekenburger J; Lebert R; Bulut K; Parry M; Meister T; Schick V; Schmitz F; Domschke W; Schmidt WE
    J Med Genet; 2008 Aug; 45(8):507-12. PubMed ID: 18511571
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism.
    Kereszturi E; Szmola R; Kukor Z; Simon P; Weiss FU; Lerch MM; Sahin-Tóth M
    Hum Mutat; 2009 Apr; 30(4):575-82. PubMed ID: 19191323
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).
    Teich N; Le Maréchal C; Kukor Z; Caca K; Witzigmann H; Chen JM; Tóth M; Mössner J; Keim V; Férec C; Sahin-Tóth M
    Hum Mutat; 2004 Jan; 23(1):22-31. PubMed ID: 14695529
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discrimination of three mutational events that result in a disruption of the R122 primary autolysis site of the human cationic trypsinogen (PRSS1) by denaturing high performance liquid chromatography.
    Le Maréchal C; Chen JM; Quéré I; Raguénès O; Férec C; Auroux J
    BMC Genet; 2001; 2():19. PubMed ID: 11734061
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C.
    Szabó A; Sahin-Tóth M
    J Biol Chem; 2012 Jun; 287(24):20701-10. PubMed ID: 22539344
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pathogenic cellular role of the p.L104P human cationic trypsinogen variant in chronic pancreatitis.
    Balázs A; Hegyi P; Sahin-Tóth M
    Am J Physiol Gastrointest Liver Physiol; 2016 Apr; 310(7):G477-86. PubMed ID: 26822915
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular pathology and evolutionary and physiological implications of pancreatitis-associated cationic trypsinogen mutations.
    Chen JM; Montier T; Férec C
    Hum Genet; 2001 Sep; 109(3):245-52. PubMed ID: 11702203
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tighter Control by Chymotrypsin C (CTRC) Explains Lack of Association between Human Anionic Trypsinogen and Hereditary Pancreatitis.
    Jancsó Z; Sahin-Tóth M
    J Biol Chem; 2016 Jun; 291(25):12897-905. PubMed ID: 27129265
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human cationic trypsinogen. Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis.
    Sahin-Tóth M
    J Biol Chem; 2000 Jul; 275(30):22750-5. PubMed ID: 10801865
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The pathobiochemistry of hereditary pancreatitis: studies on recombinant human cationic trypsinogen.
    Sahin-Tóth M
    Pancreatology; 2001; 1(5):461-5. PubMed ID: 12120225
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hereditary pancreatitis: clinical features and inheritance characteristics of the R122C mutation in the cationic trypsinogen gene (PRSS1) in six Spanish families.
    de las Heras-Castaño G; Castro-Senosiaín B; Fontalba A; López-Hoyos M; Sánchez-Juán P
    JOP; 2009 May; 10(3):249-55. PubMed ID: 19454815
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hereditary pancreatitis-associated mutation asn(21) --> ile stabilizes rat trypsinogen in vitro.
    Sahin-Tóth M
    J Biol Chem; 1999 Oct; 274(42):29699-704. PubMed ID: 10514442
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene.
    Whitcomb DC; Gorry MC; Preston RA; Furey W; Sossenheimer MJ; Ulrich CD; Martin SP; Gates LK; Amann ST; Toskes PP; Liddle R; McGrath K; Uomo G; Post JC; Ehrlich GD
    Nat Genet; 1996 Oct; 14(2):141-5. PubMed ID: 8841182
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Significance of trypsinogen gene mutations in the etiology of hereditary pancreatitis].
    Sahin-Tóth M; Tóth M
    Orv Hetil; 2001 Mar; 142(12):603-6. PubMed ID: 11324217
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutational screening of the cationic trypsinogen gene in a large cohort of subjects with idiopathic chronic pancreatitis.
    Chen JM; Piepoli Bis A; Le Bodic L; Ruszniewski P; Robaszkiewicz M; Deprez PH; Raguenes O; Quere I; Andriulli A; Ferec C
    Clin Genet; 2001 Mar; 59(3):189-93. PubMed ID: 11260229
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation.
    Kukor Z; Tóth M; Pál G; Sahin-Tóth M
    J Biol Chem; 2002 Feb; 277(8):6111-7. PubMed ID: 11748242
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trypsinogen stabilization by mutation Arg117-->His: a unifying pathomechanism for hereditary pancreatitis?
    Sahin-Tóth M; Gráf L; Tóth M
    Biochem Biophys Res Commun; 1999 Oct; 264(2):505-8. PubMed ID: 10529393
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Mutations of SPINK1 and PRSS1 gene in Korean patients with chronic pancreatitis].
    Lee KH; Yoon WJ; Ryu JK; Kim YT; Yoon YB; Kim CY
    Korean J Gastroenterol; 2004 Aug; 44(2):93-8. PubMed ID: 15329520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.