BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 11721009)

  • 1. Molecular dynamics simulations of Gly-12-->Val mutant of p21(ras): dynamic inhibition mechanism.
    Futatsugi N; Tsuda M
    Biophys J; 2001 Dec; 81(6):3483-8. PubMed ID: 11721009
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Three-dimensional structure of p21H-ras and its implications.
    Wittinghofer F
    Semin Cancer Biol; 1992 Aug; 3(4):189-98. PubMed ID: 1421163
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations.
    Grigorenko BL; Nemukhin AV; Shadrina MS; Topol IA; Burt SK
    Proteins; 2007 Feb; 66(2):456-66. PubMed ID: 17094109
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.
    Schweins T; Geyer M; Kalbitzer HR; Wittinghofer A; Warshel A
    Biochemistry; 1996 Nov; 35(45):14225-31. PubMed ID: 8916907
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dissection of the GTPase mechanism of Ras protein by MD analysis of Ras mutants.
    Friedman ZY; Devary Y
    Proteins; 2005 May; 59(3):528-33. PubMed ID: 15789417
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.
    Raw AS; Coleman DE; Gilman AG; Sprang SR
    Biochemistry; 1997 Dec; 36(50):15660-9. PubMed ID: 9398294
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A glutamic acid residue at position 31 of Ras protein is essential to the signal transduction for neurite outgrowth of PC12 cells and the stimulation of GTPase activity by GAPRas.
    Shirouzu M; Fujita-Yoshigaki J; Ito Y; Koide H; Nishimura S; Yokoyama S
    Oncogene; 1992 Mar; 7(3):475-80. PubMed ID: 1549361
    [TBL] [Abstract][Full Text] [Related]  

  • 8. What is the role of the helical domain of Gsalpha in the GTPase reaction?
    Shnerb T; Lin N; Shurki A
    Biochemistry; 2007 Sep; 46(38):10875-85. PubMed ID: 17727271
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The binding of guanine nucleotide to N-ras p21--a phosphorous and proton magnetic resonance study.
    Grand RJ; Levine BA; Byrd PJ; Gallimore PH
    Oncogene; 1989 Mar; 4(3):355-61. PubMed ID: 2649849
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression.
    Al-Mulla F; Milner-White EJ; Going JJ; Birnie GD
    J Pathol; 1999 Mar; 187(4):433-8. PubMed ID: 10398103
    [TBL] [Abstract][Full Text] [Related]  

  • 11. QM/MM modeling the Ras-GAP catalyzed hydrolysis of guanosine triphosphate.
    Grigorenko BL; Nemukhin AV; Topol IA; Cachau RE; Burt SK
    Proteins; 2005 Aug; 60(3):495-503. PubMed ID: 15906320
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ab initio study of the role of lysine 16 for the molecular switching mechanism of Ras protein p21.
    Futatsugi N; Hata M; Hoshino T; Tsuda M
    Biophys J; 1999 Dec; 77(6):3287-92. PubMed ID: 10585950
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of the hinges of the effector loop in the reaction pathway of the activation of ras-proteins. Kinetics of binding of beryllium trifluoride to V29G and I36G mutants of Ha-ras-p21.
    Kuppens S; Díaz JF; Engelborghs Y
    Protein Sci; 1999 Sep; 8(9):1860-6. PubMed ID: 10493587
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ras-catalyzed hydrolysis of GTP: a new perspective from model studies.
    Maegley KA; Admiraal SJ; Herschlag D
    Proc Natl Acad Sci U S A; 1996 Aug; 93(16):8160-6. PubMed ID: 8710841
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Raman difference studies of GDP and GTP binding to c-Harvey ras.
    Wang JH; Xiao DG; Deng H; Webb MR; Callender R
    Biochemistry; 1998 Aug; 37(31):11106-16. PubMed ID: 9693007
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism of free radical nitric oxide-mediated Ras guanine nucleotide dissociation.
    Heo J; Prutzman KC; Mocanu V; Campbell SL
    J Mol Biol; 2005 Mar; 346(5):1423-40. PubMed ID: 15713491
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Time-resolved FTIR studies of the GTPase reaction of H-ras p21 reveal a key role for the beta-phosphate.
    Cepus V; Scheidig AJ; Goody RS; Gerwert K
    Biochemistry; 1998 Jul; 37(28):10263-71. PubMed ID: 9665734
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Studies on the structure and mechanism of H-ras p21.
    Goody RS; Pai EF; Schlichting I; Rensland H; Scheidig A; Franken S; Wittinghofer A
    Philos Trans R Soc Lond B Biol Sci; 1992 Apr; 336(1276):3-10; discussion 10-1. PubMed ID: 1351293
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+.
    Schweins T; Scheffzek K; Assheuer R; Wittinghofer A
    J Mol Biol; 1997 Mar; 266(4):847-56. PubMed ID: 9102473
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The arginine finger of RasGAP helps Gln-61 align the nucleophilic water in GAP-stimulated hydrolysis of GTP.
    Resat H; Straatsma TP; Dixon DA; Miller JH
    Proc Natl Acad Sci U S A; 2001 May; 98(11):6033-8. PubMed ID: 11371635
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.