196 related articles for article (PubMed ID: 11723275)
1. Gating of myotonic Na channel mutants defines the response to mexiletine and a potent derivative.
Desaphy JF; De Luca A; Tortorella P; De Vito D; George AL; Conte Camerino D
Neurology; 2001 Nov; 57(10):1849-57. PubMed ID: 11723275
[TBL] [Abstract][Full Text] [Related]
2. Different flecainide sensitivity of hNav1.4 channels and myotonic mutants explained by state-dependent block.
Desaphy JF; De Luca A; Didonna MP; George AL; Camerino Conte D
J Physiol; 2004 Jan; 554(Pt 2):321-34. PubMed ID: 14608015
[TBL] [Abstract][Full Text] [Related]
3. Mexiletine block of disease-associated mutations in S6 segments of the human skeletal muscle Na(+) channel.
Takahashi MP; Cannon SC
J Physiol; 2001 Dec; 537(Pt 3):701-14. PubMed ID: 11744749
[TBL] [Abstract][Full Text] [Related]
4. Different effects of mexiletine on two mutant sodium channels causing paramyotonia congenita and hyperkalemic periodic paralysis.
Weckbecker K; Würz A; Mohammadi B; Mansuroglu T; George AL; Lerche H; Dengler R; Lehmann-Horn F; Mitrovic N
Neuromuscul Disord; 2000 Jan; 10(1):31-9. PubMed ID: 10677861
[TBL] [Abstract][Full Text] [Related]
5. Effects of temperature and mexiletine on the F1473S Na+ channel mutation causing paramyotonia congenita.
Fleischhauer R; Mitrovic N; Deymeer F; Lehmann-Horn F; Lerche H
Pflugers Arch; 1998 Oct; 436(5):757-65. PubMed ID: 9716710
[TBL] [Abstract][Full Text] [Related]
6. New mutation of the Na channel in the severe form of potassium-aggravated myotonia.
Kubota T; Kinoshita M; Sasaki R; Aoike F; Takahashi MP; Sakoda S; Hirose K
Muscle Nerve; 2009 May; 39(5):666-73. PubMed ID: 19347921
[TBL] [Abstract][Full Text] [Related]
7. Ranolazine block of human Na v 1.4 sodium channels and paramyotonia congenita mutants.
El-Bizri N; Kahlig KM; Shyrock JC; George AL; Belardinelli L; Rajamani S
Channels (Austin); 2011; 5(2):161-72. PubMed ID: 21317558
[TBL] [Abstract][Full Text] [Related]
8. Preferred mexiletine block of human sodium channels with IVS4 mutations and its pH-dependence.
Mohammadi B; Jurkat-Rott K; Alekov A; Dengler R; Bufler J; Lehmann-Horn F
Pharmacogenet Genomics; 2005 Apr; 15(4):235-44. PubMed ID: 15864116
[TBL] [Abstract][Full Text] [Related]
9. Biophysical characterization of M1476I, a sodium channel founder mutation associated with cold-induced myotonia in French Canadians.
Zhao J; Duprè N; Puymirat J; Chahine M
J Physiol; 2012 Jun; 590(11):2629-44. PubMed ID: 22250216
[TBL] [Abstract][Full Text] [Related]
10. A1152D mutation of the Na+ channel causes paramyotonia congenita and emphasizes the role of DIII/S4-S5 linker in fast inactivation.
Bouhours M; Luce S; Sternberg D; Willer JC; Fontaine B; Tabti N
J Physiol; 2005 Jun; 565(Pt 2):415-27. PubMed ID: 15790667
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide.
De Luca A; Natuzzi F; Falcone G; Duranti A; Lentini G; Franchini C; Tortorella V; Camerino DC
Naunyn Schmiedebergs Arch Pharmacol; 1997 Dec; 356(6):777-87. PubMed ID: 9453464
[TBL] [Abstract][Full Text] [Related]
12. Two human paramyotonia congenita mutations have opposite effects on lidocaine block of Na+ channels expressed in a mammalian cell line.
Fan Z; George AL; Kyle JW; Makielski JC
J Physiol; 1996 Oct; 496 ( Pt 1)(Pt 1):275-86. PubMed ID: 8910215
[TBL] [Abstract][Full Text] [Related]
13. Mexiletine block of wild-type and inactivation-deficient human skeletal muscle hNav1.4 Na+ channels.
Wang GK; Russell C; Wang SY
J Physiol; 2004 Feb; 554(Pt 3):621-33. PubMed ID: 14608007
[TBL] [Abstract][Full Text] [Related]
14. Leaky sodium channels from voltage sensor mutations in periodic paralysis, but not paramyotonia.
Francis DG; Rybalchenko V; Struyk A; Cannon SC
Neurology; 2011 May; 76(19):1635-41. PubMed ID: 21490317
[TBL] [Abstract][Full Text] [Related]
15. Class Ic antiarrhythmics block human skeletal muscle Na channel during myotonia-like stimulation.
Aoike F; Takahashi MP; Sakoda S
Eur J Pharmacol; 2006 Feb; 532(1-2):24-31. PubMed ID: 16473348
[TBL] [Abstract][Full Text] [Related]
16. Pharmacogenetics of myotonic hNav1.4 sodium channel variants situated near the fast inactivation gate.
Farinato A; Altamura C; Imbrici P; Maggi L; Bernasconi P; Mantegazza R; Pasquali L; Siciliano G; Lo Monaco M; Vial C; Sternberg D; Carratù MR; Conte D; Desaphy JF
Pharmacol Res; 2019 Mar; 141():224-235. PubMed ID: 30611854
[TBL] [Abstract][Full Text] [Related]
17. Stereoselective effects of mexiletine enantiomers on sodium currents and excitability characteristics of adult skeletal muscle fibers.
De Luca A; Natuzzi F; Lentini G; Franchini C; Tortorella V; Conte Camerino D
Naunyn Schmiedebergs Arch Pharmacol; 1995 Dec; 352(6):653-61. PubMed ID: 9053738
[TBL] [Abstract][Full Text] [Related]
18. Evaluation of the antimyotonic activity of mexiletine and some new analogs on sodium currents of single muscle fibers and on the abnormal excitability of the myotonic ADR mouse.
De Luca A; Pierno S; Natuzzi F; Franchini C; Duranti A; Lentini G; Tortorella V; Jockusch H; Camerino DC
J Pharmacol Exp Ther; 1997 Jul; 282(1):93-100. PubMed ID: 9223544
[TBL] [Abstract][Full Text] [Related]
19. Defective slow inactivation of sodium channels contributes to familial periodic paralysis.
Hayward LJ; Sandoval GM; Cannon SC
Neurology; 1999 Apr; 52(7):1447-53. PubMed ID: 10227633
[TBL] [Abstract][Full Text] [Related]
20. Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide.
Desaphy JF; Dipalma A; Costanza T; Bruno C; Lentini G; Franchini C; George A; Conte Camerino D
Br J Pharmacol; 2010 Jul; 160(6):1521-33. PubMed ID: 20590641
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
