BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 11724749)

  • 1. Antisense-induced down-regulation of thymidylate synthase and enhanced cytotoxicity of 5-FUdR in 5-FUdR-resistant HeLa cells.
    Ferguson PJ; DeMoor JM; Vincent MD; Koropatnick J
    Br J Pharmacol; 2001 Dec; 134(7):1437-46. PubMed ID: 11724749
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antisense down-regulation of thymidylate synthase to suppress growth and enhance cytotoxicity of 5-FUdR, 5-FU and Tomudex in HeLa cells.
    Ferguson PJ; Collins O; Dean NM; DeMoor J; Li CS; Vincent MD; Koropatnick J
    Br J Pharmacol; 1999 Aug; 127(8):1777-86. PubMed ID: 10482907
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The means to an end of tumor cell resistance to chemotherapeutic drugs targeting thymidylate synthase: shoot the messenger.
    Berg RW; Ferguso PJ; DeMoor JM; Vincen MD; Koropatnick J
    Curr Drug Targets; 2002 Aug; 3(4):297-309. PubMed ID: 12102601
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thymidylate synthase mRNA expression does not predict resistance to floxuridine in a choriocarcinoma cell line.
    Han B; Xiang Y; Sha GH; Zhang H; Liu X
    J Reprod Med; 2010; 55(5-6):247-52. PubMed ID: 20626181
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of thymidylate synthase activity by antisense oligodeoxynucleotide and possible role in thymineless treatment.
    Lin SB; Ts'o PO; Sun SK; Choo KB; Yang FY; Lim YP; Tsai HL; Au LC
    Mol Pharmacol; 2001 Sep; 60(3):474-9. PubMed ID: 11502877
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tumor growth inhibition in vivo and G2/M cell cycle arrest induced by antisense oligodeoxynucleotide targeting thymidylate synthase.
    Berg RW; Werner M; Ferguson PJ; Postenka C; Vincent M; Koropatnick DJ; Behrend E
    J Pharmacol Exp Ther; 2001 Aug; 298(2):477-84. PubMed ID: 11454908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Desensitization and sensitization of cells to fluoropyrimidines with different antisenses directed against thymidylate synthase messenger RNA.
    Ju J; Kane SE; Lenz HJ; Danenberg KD; Chu E; Danenberg PV
    Clin Cancer Res; 1998 Sep; 4(9):2229-36. PubMed ID: 9748143
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ODN 491, a novel antisense oligodeoxynucleotide that targets thymidylate synthase, exerts cell-specific effects in human tumor cell lines.
    Jason TL; Figueredo R; Ferguson PJ; Vincent MD; Berg RW; Koropatnick J
    DNA Cell Biol; 2008 May; 27(5):229-40. PubMed ID: 18358073
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Polymorphic tandem repeat sequences of the thymidylate synthase gene correlates with cellular-based sensitivity to fluoropyrimidine antitumor agents.
    Yawata A; Kim SR; Miyajima A; Kubo T; Ishida S; Saito Y; Nakajima Y; Katori N; Matsumoto Y; Fukuoka M; Ohno Y; Ozawa S; Sawada J
    Cancer Chemother Pharmacol; 2005 Nov; 56(5):465-72. PubMed ID: 15918040
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A "combination oligonucleotide" antisense strategy to downregulate thymidylate synthase and decrease tumor cell growth and drug resistance.
    Berg RW; Ferguson PJ; Vincent MD; Koropatnick DJ
    Cancer Gene Ther; 2003 Apr; 10(4):278-86. PubMed ID: 12679800
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The transfection of thymidylate synthase antisense suppresses oncogenic properties of a human colon cancer cell line and augments the antitumor effect of fluorouracil.
    Matsuoka K; Tsukuda K; Suda M; Kobayashi K; Ota T; Okita A; Watanabe K; Suzuki E; Murakami M; Doihara H; Shimizu N
    Int J Oncol; 2004 Jan; 24(1):217-22. PubMed ID: 14654960
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Combining small interfering RNAs targeting thymidylate synthase and thymidine kinase 1 or 2 sensitizes human tumor cells to 5-fluorodeoxyuridine and pemetrexed.
    Di Cresce C; Figueredo R; Ferguson PJ; Vincent MD; Koropatnick J
    J Pharmacol Exp Ther; 2011 Sep; 338(3):952-63. PubMed ID: 21673071
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antisense targeting of thymidylate synthase (TS) mRNA increases TS gene transcription and TS protein: effects on human tumor cell sensitivity to TS enzyme-inhibiting drugs.
    Jason TL; Berg RW; Vincent MD; Koropatnick J
    Gene Expr; 2007; 13(4-5):227-39. PubMed ID: 17605297
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Resistance of colorectal cancer cells to 5-FUdR and 5-FU caused by Mycoplasma infection.
    Jetté L; Bissoon-Haqqani S; Le François B; Maroun JA; Birnboim HC
    Anticancer Res; 2008; 28(4B):2175-80. PubMed ID: 18751392
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antisense nucleic acids targeted to the thymidylate synthase (TS) mRNA translation start site stimulate TS gene transcription.
    DeMoor JM; Vincent MD; Collins OM; Koropatnick J
    Exp Cell Res; 1998 Aug; 243(1):11-21. PubMed ID: 9716444
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen.
    Grem JL; Danenberg KD; Behan K; Parr A; Young L; Danenberg PV; Nguyen D; Drake J; Monks A; Allegra CJ
    Clin Cancer Res; 2001 Apr; 7(4):999-1009. PubMed ID: 11309351
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells.
    Berger SH; Jenh CH; Johnson LF; Berger FG
    Mol Pharmacol; 1985 Nov; 28(5):461-7. PubMed ID: 2932632
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combination silencer RNA (siRNA) targeting Bcl-2 antagonizes siRNA against thymidylate synthase in human tumor cell lines.
    Pandyra AA; Berg R; Vincent M; Koropatnick J
    J Pharmacol Exp Ther; 2007 Jul; 322(1):123-32. PubMed ID: 17452420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Recent advances in the study of rTS proteins. rTS expression during growth and in response to thymidylate synthase inhibitors in human tumor cells.
    Dolnick BJ; Lu K; Yin MB; Rustum YM
    Adv Enzyme Regul; 1997; 37():95-109. PubMed ID: 9381988
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanisms of acquired chemoresistance to 5-fluorouracil and tomudex: thymidylate synthase dependent and independent networks.
    Wang W; McLeod HL; Cassidy J; Collie-Duguid ES
    Cancer Chemother Pharmacol; 2007 May; 59(6):839-45. PubMed ID: 17119966
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.