262 related articles for article (PubMed ID: 11726500)
1. Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.
Sotillo R; Dubus P; Martín J; de la Cueva E; Ortega S; Malumbres M; Barbacid M
EMBO J; 2001 Dec; 20(23):6637-47. PubMed ID: 11726500
[TBL] [Abstract][Full Text] [Related]
2. Cooperation between Cdk4 and p27kip1 in tumor development: a preclinical model to evaluate cell cycle inhibitors with therapeutic activity.
Sotillo R; Renner O; Dubus P; Ruiz-Cabello J; Martín-Caballero J; Barbacid M; Carnero A; Malumbres M
Cancer Res; 2005 May; 65(9):3846-52. PubMed ID: 15867383
[TBL] [Abstract][Full Text] [Related]
3. Genetic evidence for functional dependency of p18Ink4c on Cdk4.
Pei XH; Bai F; Tsutsui T; Kiyokawa H; Xiong Y
Mol Cell Biol; 2004 Aug; 24(15):6653-64. PubMed ID: 15254233
[TBL] [Abstract][Full Text] [Related]
4. Activating point mutations in cyclin-dependent kinase 4 are not seen in sporadic pituitary adenomas, insulinomas or Leydig cell tumours.
Vax VV; Bibi R; Diaz-Cano S; Gueorguiev M; Kola B; Borboli N; Bressac-de Paillerets B; Walker GJ; Dedov II; Grossman AB; Korbonits M
J Endocrinol; 2003 Aug; 178(2):301-10. PubMed ID: 12904177
[TBL] [Abstract][Full Text] [Related]
5. Invasive melanoma in Cdk4-targeted mice.
Sotillo R; García JF; Ortega S; Martin J; Dubus P; Barbacid M; Malumbres M
Proc Natl Acad Sci U S A; 2001 Nov; 98(23):13312-7. PubMed ID: 11606789
[TBL] [Abstract][Full Text] [Related]
6. Regulation of cyclin-dependent kinase 4 during adipogenesis involves switching of cyclin D subunits and concurrent binding of p18INK4c and p27Kip1.
Phelps DE; Xiong Y
Cell Growth Differ; 1998 Aug; 9(8):595-610. PubMed ID: 9716177
[TBL] [Abstract][Full Text] [Related]
7. A single nucleotide polymorphism in the 3'untranslated region of the CDKN2A gene is common in sporadic primary melanomas but mutations in the CDKN2B, CDKN2C, CDK4 and p53 genes are rare.
Kumar R; Smeds J; Berggren P; Straume O; Rozell BL; Akslen LA; Hemminki K
Int J Cancer; 2001 Nov; 95(6):388-93. PubMed ID: 11668523
[TBL] [Abstract][Full Text] [Related]
8. Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence.
Rane SG; Cosenza SC; Mettus RV; Reddy EP
Mol Cell Biol; 2002 Jan; 22(2):644-56. PubMed ID: 11756559
[TBL] [Abstract][Full Text] [Related]
9. The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis.
Bartkova J; Lukas J; Guldberg P; Alsner J; Kirkin AF; Zeuthen J; Bartek J
Cancer Res; 1996 Dec; 56(23):5475-83. PubMed ID: 8968104
[TBL] [Abstract][Full Text] [Related]
10. Individuals with presumably hereditary uveal melanoma do not harbour germline mutations in the coding regions of either the P16INK4A, P14ARF or cdk4 genes.
Soufir N; Bressac-de Paillerets B; Desjardins L; Lévy C; Bombled J; Gorin I; Schlienger P; Stoppa-Lyonnet D
Br J Cancer; 2000 Feb; 82(4):818-22. PubMed ID: 10732752
[TBL] [Abstract][Full Text] [Related]
11. Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras mice.
Hacker E; Muller HK; Irwin N; Gabrielli B; Lincoln D; Pavey S; Powell MB; Malumbres M; Barbacid M; Hayward N; Walker G
Cancer Res; 2006 Mar; 66(6):2946-52. PubMed ID: 16540642
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of Cdk4 activity enhances translation of p27kip1 in quiescent Rb-negative cells.
González T; Seoane M; Caamaño P; Viñuela J; Domínguez F; Zalvide J
J Biol Chem; 2003 Apr; 278(15):12688-95. PubMed ID: 12566456
[TBL] [Abstract][Full Text] [Related]
13. Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function.
Foster JS; Henley DC; Bukovsky A; Seth P; Wimalasena J
Mol Cell Biol; 2001 Feb; 21(3):794-810. PubMed ID: 11154267
[TBL] [Abstract][Full Text] [Related]
14. Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras.
Tremain R; Marko M; Kinnimulki V; Ueno H; Bottinger E; Glick A
Oncogene; 2000 Mar; 19(13):1698-709. PubMed ID: 10763827
[TBL] [Abstract][Full Text] [Related]
15. An NF-kappaB-specific inhibitor, IkappaBalpha, binds to and inhibits cyclin-dependent kinase 4.
Li J; Joo SH; Tsai MD
Biochemistry; 2003 Nov; 42(46):13476-83. PubMed ID: 14621993
[TBL] [Abstract][Full Text] [Related]
16. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.
Zou X; Ray D; Aziyu A; Christov K; Boiko AD; Gudkov AV; Kiyokawa H
Genes Dev; 2002 Nov; 16(22):2923-34. PubMed ID: 12435633
[TBL] [Abstract][Full Text] [Related]
17. Activation of cyclin D1-kinase in murine fibroblasts lacking both p21(Cip1) and p27(Kip1).
Sugimoto M; Martin N; Wilks DP; Tamai K; Huot TJ; Pantoja C; Okumura K; Serrano M; Hara E
Oncogene; 2002 Nov; 21(53):8067-74. PubMed ID: 12444543
[TBL] [Abstract][Full Text] [Related]
18. p21 loss cooperates with INK4 inactivation facilitating immortalization and Bcl-2-mediated anchorage-independent growth of oncogene-transduced primary mouse fibroblasts.
Carbone CJ; Graña X; Reddy EP; Haines DS
Cancer Res; 2007 May; 67(9):4130-7. PubMed ID: 17483323
[TBL] [Abstract][Full Text] [Related]
19. Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppression.
Quereda V; Martinalbo J; Dubus P; Carnero A; Malumbres M
Oncogene; 2007 Dec; 26(55):7665-74. PubMed ID: 17599058
[TBL] [Abstract][Full Text] [Related]
20. Homozygous deletion of the MTS1/p16 and MTS2/p15 genes and amplification of the CDK4 gene in glioma.
Sonoda Y; Yoshimoto T; Sekiya T
Oncogene; 1995 Nov; 11(10):2145-9. PubMed ID: 7478535
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
