149 related articles for article (PubMed ID: 11727316)
1. Computational methods to predict drug safety liabilities.
Durham SK; Pearl GM
Curr Opin Drug Discov Devel; 2001 Jan; 4(1):110-5. PubMed ID: 11727316
[TBL] [Abstract][Full Text] [Related]
2. Assessment of the sensitivity of the computational programs DEREK, TOPKAT, and MCASE in the prediction of the genotoxicity of pharmaceutical molecules.
Snyder RD; Pearl GS; Mandakas G; Choy WN; Goodsaid F; Rosenblum IY
Environ Mol Mutagen; 2004; 43(3):143-58. PubMed ID: 15065202
[TBL] [Abstract][Full Text] [Related]
3. Computational methods to estimate drug development parameters.
Podlogar BL; Muegge I; Brice LJ
Curr Opin Drug Discov Devel; 2001 Jan; 4(1):102-9. PubMed ID: 11727315
[TBL] [Abstract][Full Text] [Related]
4. In silico methods for early toxicity assessment.
Merlot C
Curr Opin Drug Discov Devel; 2008 Jan; 11(1):80-5. PubMed ID: 18175270
[TBL] [Abstract][Full Text] [Related]
5. In silico toxicology for the pharmaceutical sciences.
Valerio LG
Toxicol Appl Pharmacol; 2009 Dec; 241(3):356-70. PubMed ID: 19716836
[TBL] [Abstract][Full Text] [Related]
6. Computational toxicology--a tool for early safety evaluation.
Merlot C
Drug Discov Today; 2010 Jan; 15(1-2):16-22. PubMed ID: 19835978
[TBL] [Abstract][Full Text] [Related]
7. Progress in QSAR toxicity screening of pharmaceutical impurities and other FDA regulated products.
Kruhlak NL; Contrera JF; Benz RD; Matthews EJ
Adv Drug Deliv Rev; 2007 Jan; 59(1):43-55. PubMed ID: 17229485
[TBL] [Abstract][Full Text] [Related]
8. Prediction of rodent carcinogenic potential of naturally occurring chemicals in the human diet using high-throughput QSAR predictive modeling.
Valerio LG; Arvidson KB; Chanderbhan RF; Contrera JF
Toxicol Appl Pharmacol; 2007 Jul; 222(1):1-16. PubMed ID: 17482223
[TBL] [Abstract][Full Text] [Related]
9. Integrated decision support for assessing chemical liabilities.
Spjuth O; Eklund M; Ahlberg Helgee E; Boyer S; Carlsson L
J Chem Inf Model; 2011 Aug; 51(8):1840-7. PubMed ID: 21774475
[TBL] [Abstract][Full Text] [Related]
10. Towards improving compound selection in structure-based virtual screening.
Waszkowycz B
Drug Discov Today; 2008 Mar; 13(5-6):219-26. PubMed ID: 18342797
[TBL] [Abstract][Full Text] [Related]
11. The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates.
Kramer JA; Sagartz JE; Morris DL
Nat Rev Drug Discov; 2007 Aug; 6(8):636-49. PubMed ID: 17643090
[TBL] [Abstract][Full Text] [Related]
12. Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development.
Whitebread S; Hamon J; Bojanic D; Urban L
Drug Discov Today; 2005 Nov; 10(21):1421-33. PubMed ID: 16243262
[TBL] [Abstract][Full Text] [Related]
13. A structural feature-based computational approach for toxicology predictions.
Valerio LG; Yang C; Arvidson KB; Kruhlak NL
Expert Opin Drug Metab Toxicol; 2010 Apr; 6(4):505-18. PubMed ID: 20074001
[TBL] [Abstract][Full Text] [Related]
14. Multi-dimensional QSAR in drug discovery.
Lill MA
Drug Discov Today; 2007 Dec; 12(23-24):1013-7. PubMed ID: 18061879
[TBL] [Abstract][Full Text] [Related]
15. Computational methods for the prediction of drug toxicity.
Cronin MT
Curr Opin Drug Discov Devel; 2000 May; 3(3):292-7. PubMed ID: 19649861
[TBL] [Abstract][Full Text] [Related]
16. The challenge of predicting drug toxicity in silico.
Vedani A; Dobler M; Lill MA
Basic Clin Pharmacol Toxicol; 2006 Sep; 99(3):195-208. PubMed ID: 16930291
[TBL] [Abstract][Full Text] [Related]
17. The many roles of computation in drug discovery.
Jorgensen WL
Science; 2004 Mar; 303(5665):1813-8. PubMed ID: 15031495
[TBL] [Abstract][Full Text] [Related]
18. Computational toxicology in drug development.
Muster W; Breidenbach A; Fischer H; Kirchner S; Müller L; Pähler A
Drug Discov Today; 2008 Apr; 13(7-8):303-10. PubMed ID: 18405842
[TBL] [Abstract][Full Text] [Related]
19. Computational studies of epidermal growth factor receptor: docking reliability, three-dimensional quantitative structure-activity relationship analysis, and virtual screening studies.
La Motta C; Sartini S; Tuccinardi T; Nerini E; Da Settimo F; Martinelli A
J Med Chem; 2009 Feb; 52(4):964-75. PubMed ID: 19170633
[TBL] [Abstract][Full Text] [Related]
20. Predictive value of in vitro safety studies.
Suter W
Curr Opin Chem Biol; 2006 Aug; 10(4):362-6. PubMed ID: 16815733
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]