BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 11727325)

  • 1. Integrating metabolism and toxicity in multi-organ systems.
    Madden S; Bach PH
    Curr Opin Drug Discov Devel; 2001 Jan; 4(1):66-72. PubMed ID: 11727325
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
    EFSA GMO Panel Working Group on Animal Feeding Trials
    Food Chem Toxicol; 2008 Mar; 46 Suppl 1():S2-70. PubMed ID: 18328408
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico toxicology for the pharmaceutical sciences.
    Valerio LG
    Toxicol Appl Pharmacol; 2009 Dec; 241(3):356-70. PubMed ID: 19716836
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development and validation of in silico models for estimating drug preformulation risk in PEG400/water and Tween80/water systems.
    Crivori P; Morelli A; Pezzetta D; Rocchetti M; Poggesi I
    Eur J Pharm Sci; 2007 Nov; 32(3):169-81. PubMed ID: 17714921
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Early prediction of drug metabolism and toxicity: systems biology approach and modeling.
    Bugrim A; Nikolskaya T; Nikolsky Y
    Drug Discov Today; 2004 Feb; 9(3):127-35. PubMed ID: 14960390
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The challenge of predicting drug toxicity in silico.
    Vedani A; Dobler M; Lill MA
    Basic Clin Pharmacol Toxicol; 2006 Sep; 99(3):195-208. PubMed ID: 16930291
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Elucidating mechanisms of drug-induced toxicity.
    Liebler DC; Guengerich FP
    Nat Rev Drug Discov; 2005 May; 4(5):410-20. PubMed ID: 15864270
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Use of computer-assisted prediction of toxic effects of chemical substances.
    Simon-Hettich B; Rothfuss A; Steger-Hartmann T
    Toxicology; 2006 Jul; 224(1-2):156-62. PubMed ID: 16707203
    [TBL] [Abstract][Full Text] [Related]  

  • 9. What have we learned from pre-clinical juvenile toxicity studies?
    Bailey GP; Mariƫn D
    Reprod Toxicol; 2009 Sep; 28(2):226-9. PubMed ID: 19446432
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Understanding mechanisms of toxicity: insights from drug discovery research.
    Houck KA; Kavlock RJ
    Toxicol Appl Pharmacol; 2008 Mar; 227(2):163-78. PubMed ID: 18063003
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A combined approach to drug metabolism and toxicity assessment.
    Ekins S; Andreyev S; Ryabov A; Kirillov E; Rakhmatulin EA; Sorokina S; Bugrim A; Nikolskaya T
    Drug Metab Dispos; 2006 Mar; 34(3):495-503. PubMed ID: 16381662
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Beyond profiling: using ADMET models to guide decisions.
    Segall M; Champness E; Obrezanova O; Leeding C
    Chem Biodivers; 2009 Nov; 6(11):2144-51. PubMed ID: 19937845
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Assessment of three human in vitro systems in the generation of major human excretory and circulating metabolites.
    Dalvie D; Obach RS; Kang P; Prakash C; Loi CM; Hurst S; Nedderman A; Goulet L; Smith E; Bu HZ; Smith DA
    Chem Res Toxicol; 2009 Feb; 22(2):357-68. PubMed ID: 19146377
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Physiochemical drug properties associated with in vivo toxicological outcomes.
    Hughes JD; Blagg J; Price DA; Bailey S; Decrescenzo GA; Devraj RV; Ellsworth E; Fobian YM; Gibbs ME; Gilles RW; Greene N; Huang E; Krieger-Burke T; Loesel J; Wager T; Whiteley L; Zhang Y
    Bioorg Med Chem Lett; 2008 Sep; 18(17):4872-5. PubMed ID: 18691886
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Emerging applications of kinetic biomarkers in preclinical and clinical drug development.
    Turner SM; Hellerstein MK
    Curr Opin Drug Discov Devel; 2005 Jan; 8(1):115-26. PubMed ID: 15679179
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Predictive tools for the evaluation of microbial effects on drugs during gastrointestinal passage.
    Pieper IA; Bertau M
    Expert Opin Drug Metab Toxicol; 2010 Jun; 6(6):747-60. PubMed ID: 20367108
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of pharmacology data and the prediction of adverse drug reactions and off-target effects from chemical structure.
    Bender A; Scheiber J; Glick M; Davies JW; Azzaoui K; Hamon J; Urban L; Whitebread S; Jenkins JL
    ChemMedChem; 2007 Jun; 2(6):861-73. PubMed ID: 17477341
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Predicting ADME properties and side effects: the BioPrint approach.
    Krejsa CM; Horvath D; Rogalski SL; Penzotti JE; Mao B; Barbosa F; Migeon JC
    Curr Opin Drug Discov Devel; 2003 Jul; 6(4):470-80. PubMed ID: 12951810
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Predicting human pharmacokinetics from preclinical data.
    Poggesi I
    Curr Opin Drug Discov Devel; 2004 Jan; 7(1):100-11. PubMed ID: 14982153
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Complicating factors in safety testing of drug metabolites: kinetic differences between generated and preformed metabolites.
    Prueksaritanont T; Lin JH; Baillie TA
    Toxicol Appl Pharmacol; 2006 Dec; 217(2):143-52. PubMed ID: 17055014
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.