194 related articles for article (PubMed ID: 11731271)
1. Cathepsin D cleaves aggrecan at unique sites within the interglobular domain and chondroitin sulfate attachment regions that are also cleaved when cartilage is maintained at acid pH.
Handley CJ; Mok MT; Ilic MZ; Adcocks C; Buttle DJ; Robinson HC
Matrix Biol; 2001 Dec; 20(8):543-53. PubMed ID: 11731271
[TBL] [Abstract][Full Text] [Related]
2. Characterization of aggrecan retained and lost from the extracellular matrix of articular cartilage. Involvement of carboxyl-terminal processing in the catabolism of aggrecan.
Ilic MZ; Robinson HC; Handley CJ
J Biol Chem; 1998 Jul; 273(28):17451-8. PubMed ID: 9651333
[TBL] [Abstract][Full Text] [Related]
3. Mechanism of catabolism of aggrecan by articular cartilage.
Ilic MZ; Handley CJ; Robinson HC; Mok MT
Arch Biochem Biophys; 1992 Apr; 294(1):115-22. PubMed ID: 1550337
[TBL] [Abstract][Full Text] [Related]
4. Highly sulfated glycosaminoglycans inhibit aggrecanase degradation of aggrecan by bovine articular cartilage explant cultures.
Munteanu SE; Ilic MZ; Handley CJ
Matrix Biol; 2002 Aug; 21(5):429-40. PubMed ID: 12225808
[TBL] [Abstract][Full Text] [Related]
5. Catabolism of aggrecan by explant cultures of human articular cartilage in the presence of retinoic acid.
Ilic MZ; Mok MT; Williamson OD; Campbell MA; Hughes CE; Handley CJ
Arch Biochem Biophys; 1995 Sep; 322(1):22-30. PubMed ID: 7574678
[TBL] [Abstract][Full Text] [Related]
6. The intermediates of aggrecanase-dependent cleavage of aggrecan in rat chondrosarcoma cells treated with interleukin-1.
Sandy JD; Thompson V; Doege K; Verscharen C
Biochem J; 2000 Oct; 351(Pt 1):161-6. PubMed ID: 10998358
[TBL] [Abstract][Full Text] [Related]
7. Mature bovine articular cartilage contains abundant aggrecan that is C-terminally truncated at Ala719-Ala720, a site which is readily cleaved by m-calpain.
Oshita H; Sandy JD; Suzuki K; Akaike A; Bai Y; Sasaki T; Shimizu K
Biochem J; 2004 Aug; 382(Pt 1):253-9. PubMed ID: 15175011
[TBL] [Abstract][Full Text] [Related]
8. The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases, and cathepsin B.
Fosang AJ; Neame PJ; Last K; Hardingham TE; Murphy G; Hamilton JA
J Biol Chem; 1992 Sep; 267(27):19470-4. PubMed ID: 1326552
[TBL] [Abstract][Full Text] [Related]
9. The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain.
Sandy JD; Flannery CR; Neame PJ; Lohmander LS
J Clin Invest; 1992 May; 89(5):1512-6. PubMed ID: 1569188
[TBL] [Abstract][Full Text] [Related]
10. Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro.
Little CB; Flannery CR; Hughes CE; Mort JS; Roughley PJ; Dent C; Caterson B
Biochem J; 1999 Nov; 344 Pt 1(Pt 1):61-8. PubMed ID: 10548534
[TBL] [Abstract][Full Text] [Related]
11. Quantification of a matrix metalloproteinase-generated aggrecan G1 fragment using monospecific anti-peptide serum.
Lark MW; Williams H; Hoernner LA; Weidner J; Ayala JM; Harper CF; Christen A; Olszewski J; Konteatis Z; Webber R
Biochem J; 1995 Apr; 307 ( Pt 1)(Pt 1):245-52. PubMed ID: 7717983
[TBL] [Abstract][Full Text] [Related]
12. ADAMTS-1 cleaves a cartilage proteoglycan, aggrecan.
Kuno K; Okada Y; Kawashima H; Nakamura H; Miyasaka M; Ohno H; Matsushima K
FEBS Lett; 2000 Aug; 478(3):241-5. PubMed ID: 10930576
[TBL] [Abstract][Full Text] [Related]
13. Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation.
Little CB; Hughes CE; Curtis CL; Janusz MJ; Bohne R; Wang-Weigand S; Taiwo YO; Mitchell PG; Otterness IG; Flannery CR; Caterson B
Matrix Biol; 2002 Apr; 21(3):271-88. PubMed ID: 12009333
[TBL] [Abstract][Full Text] [Related]
14. The interglobular domain of cartilage aggrecan is cleaved by hemorrhagic metalloproteinase HT-d (atrolysin C) at the matrix metalloproteinase and aggrecanase sites.
Tortorella MD; Pratta MA; Fox JW; Arner EC
J Biol Chem; 1998 Mar; 273(10):5846-50. PubMed ID: 9488721
[TBL] [Abstract][Full Text] [Related]
15. The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis.
Lohmander LS; Neame PJ; Sandy JD
Arthritis Rheum; 1993 Sep; 36(9):1214-22. PubMed ID: 8216415
[TBL] [Abstract][Full Text] [Related]
16. Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain.
Sandy JD; Neame PJ; Boynton RE; Flannery CR
J Biol Chem; 1991 May; 266(14):8683-5. PubMed ID: 2026585
[TBL] [Abstract][Full Text] [Related]
17. N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1-treated articular-cartilage cultures. Putative site(s) of enzymic cleavage.
Loulakis P; Shrikhande A; Davis G; Maniglia CA
Biochem J; 1992 Jun; 284 ( Pt 2)(Pt 2):589-93. PubMed ID: 1599440
[TBL] [Abstract][Full Text] [Related]
18. Hyaluronan-binding region of aggrecan from pig laryngeal cartilage. Amino acid sequence, analysis of N-linked oligosaccharides and location of the keratan sulphate.
Barry FP; Gaw JU; Young CN; Neame PJ
Biochem J; 1992 Sep; 286 ( Pt 3)(Pt 3):761-9. PubMed ID: 1417734
[TBL] [Abstract][Full Text] [Related]
19. Distribution of newly synthesized aggrecan in explant cultures of bovine cartilage treated with retinoic acid.
Handley CJ; Winter GM; Ilic MZ; Ross JM; Anthony Poole C; Clem Robinson H
Matrix Biol; 2002 Nov; 21(7):579-92. PubMed ID: 12475642
[TBL] [Abstract][Full Text] [Related]
20. Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation.
Hou WS; Li Z; Büttner FH; Bartnik E; Brömme D
Biol Chem; 2003 Jun; 384(6):891-7. PubMed ID: 12887056
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]