These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 11731293)

  • 1. Synthesis and biological evaluation of all A-ring stereoisomers of 5,6-trans-2-methyl-1,25-dihydroxyvitamin D(3) and their 20-epimers: possible binding modes of potent A-ring analogues to vitamin D receptor.
    Fujishima T; Konno K; Nakagawa K; Tanaka M; Okano T; Kurihara M; Miyata N; Takayama H
    Chem Biol; 2001 Nov; 8(11):1011-24. PubMed ID: 11731293
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel ring A stereoisomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 2-methyl-20-epi-1alpha,25-dihydroxyvitamin D(3): transactivation of target genes and modulation of differentiation in human promyelocytic leukemia (HL-60) cells.
    Nakagawa K; Kurobe M; Ozono K; Konno K; Fujishima T; Takayama H; Okano T
    Biochem Pharmacol; 2000 Mar; 59(6):691-702. PubMed ID: 10677586
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, biological evaluation, and conformational analysis of A-ring diastereomers of 2-methyl-1,25-dihydroxyvitamin D(3) and their 20-epimers: unique activity profiles depending on the stereochemistry of the A-ring and at C-20.
    Konno K; Fujishima T; Maki S; Liu Z; Miura D; Chokki M; Ishizuka S; Yamaguchi K; Kan Y; Kurihara M; Miyata N; Smith C; DeLuca HF; Takayama H
    J Med Chem; 2000 Nov; 43(22):4247-65. PubMed ID: 11063621
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Highly potent cell differentiation-inducing analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and biological activity of 2-methyl-1,25-dihydroxyvitamin D3 with side-chain modifications.
    Fujishima T; Zhaopeng L; Konno K; Nakagawa K; Okano T; Yamaguchi K; Takayama H
    Bioorg Med Chem; 2001 Feb; 9(2):525-35. PubMed ID: 11249144
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Methyl-introduced A-ring analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and biological evaluation.
    Fujishima T; Tsutsumi R; Negishi Y; Fujii S; Takayama H; Kittaka A; Kurihara M
    Anticancer Res; 2006; 26(4A):2633-6. PubMed ID: 16886673
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Systematic studies on synthesis, structural elucidation, and biological evaluation of A-ring diastereomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 20-epi-2-methyl-1alpha,25-dihydroxyvitamin D(3).
    Takayama H; Konno K; Fujishima T; Maki S; Liu Z; Miura D; Chokki M; Ishizuka S; Smith C; DeLuca HF; Nakagawa K; Kurobe M; Okano T
    Steroids; 2001; 66(3-5):277-85. PubMed ID: 11179735
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological studies of the A-ring-modified 1,25-dihydroxyvitamin D3 analogs.
    Takayama H; Kittaka A; Fujishima T; Suhara Y
    Recent Results Cancer Res; 2003; 164():289-317. PubMed ID: 12899530
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Syntheses and biological evaluation of novel 2alpha-substituted 1alpha,25-dihydroxyvitamin D3 analogues.
    Suhara Y; Nihei KI; Tanigawa H; Fujishima T; Konno K; Nakagawa K; Okano T; Takayama H
    Bioorg Med Chem Lett; 2000 May; 10(10):1129-32. PubMed ID: 10843234
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure.
    Shimizu M; Miyamoto Y; Takaku H; Matsuo M; Nakabayashi M; Masuno H; Udagawa N; DeLuca HF; Ikura T; Ito N
    Bioorg Med Chem; 2008 Jul; 16(14):6949-64. PubMed ID: 18539034
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fluorinated vitamin D analogs to probe the conformation of vitamin D in its receptor complex: 19F-NMR studies and biological activity.
    Ohno A; Shimizu M; Yamada S
    Chem Pharm Bull (Tokyo); 2002 Apr; 50(4):475-83. PubMed ID: 11963993
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Structural refinement of seco-steroidal skeleton and the biological activity through nuclear receptors].
    Kittaka A
    Yakugaku Zasshi; 2008 Sep; 128(9):1235-50. PubMed ID: 18758137
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3.
    Boehm MF; Fitzgerald P; Zou A; Elgort MG; Bischoff ED; Mere L; Mais DE; Bissonnette RP; Heyman RA; Nadzan AM; Reichman M; Allegretto EA
    Chem Biol; 1999 May; 6(5):265-75. PubMed ID: 10322128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of novel 1,25-dihydroxyvitamin D3 analogues having a spiro-oxetane fused at the C2 position in the A-ring.
    Fujishima T; Nozaki T; Suenaga T
    Bioorg Med Chem; 2013 Sep; 21(17):5209-17. PubMed ID: 23845283
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro biological activities of a series of 2 beta-substituted analogues of 1 alpha,25-dihydroxyvitamin D3.
    Tsugawa N; Nakagawa K; Kurobe M; Ono Y; Kubodera N; Ozono K; Okano T
    Biol Pharm Bull; 2000 Jan; 23(1):66-71. PubMed ID: 10706413
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vitamin D analogue-specific recruitment of vitamin D receptor coactivators.
    Issa LL; Leong GM; Sutherland RL; Eisman JA
    J Bone Miner Res; 2002 May; 17(5):879-90. PubMed ID: 12009019
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multifunctional and potent roles of the 3-hydroxypropoxy group provide eldecalcitol's benefit in osteoporosis treatment.
    Ono Y
    J Steroid Biochem Mol Biol; 2014 Jan; 139():88-97. PubMed ID: 24139874
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A perspective on how the Vitamin D sterol/Vitamin D receptor (VDR) conformational ensemble model can potentially be used to understand the structure-function results of A-ring modified Vitamin D sterols.
    Mizwicki MT; Bula CM; Bishop JE; Norman AW
    J Steroid Biochem Mol Biol; 2005 Oct; 97(1-2):69-82. PubMed ID: 16055325
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Singly dehydroxylated A-ring analogues of 19-nor-1alpha,25-dihydroxyvitamin D3 and 19-nor-22-oxa-1alpha,25-dihydroxyvitamin D3: novel vitamin D3 analogues with potent transcriptional activity but extremely low affinity for vitamin D receptor.
    Okano T; Nakagawa K; Tsugawa N; Ozono K; Kubodera N; Osawa A; Terada M; Mikami K
    Biol Pharm Bull; 1998 Dec; 21(12):1300-5. PubMed ID: 9881643
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological activity of 2-methyl-20-epi analogues of 1 alpha,25-dihydroxyvitamin D3.
    Fujishima T; Liu Z; Miura D; Chokki M; Ishizuka S; Konno K; Takayama H
    Bioorg Med Chem Lett; 1998 Aug; 8(16):2145-8. PubMed ID: 9873502
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of 1α,25-dihydroxyvitamin D3 analogues with aromatic side chains attached at C-17.
    Liu C; Zhao GD; Mao X; Suenaga T; Fujishima T; Zhang CM; Liu ZP
    Eur J Med Chem; 2014 Oct; 85():569-75. PubMed ID: 25127149
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.