271 related articles for article (PubMed ID: 11731295)
1. The inefficiency of incisions of ecteinascidin 743-DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent.
Zewail-Foote M; Li VS; Kohn H; Bearss D; Guzman M; Hurley LH
Chem Biol; 2001 Nov; 8(11):1033-49. PubMed ID: 11731295
[TBL] [Abstract][Full Text] [Related]
2. Differential rates of reversibility of ecteinascidin 743-DNA covalent adducts from different sequences lead to migration to favored bonding sites.
Zewail-Foote M; Hurley LH
J Am Chem Soc; 2001 Jul; 123(27):6485-95. PubMed ID: 11439034
[TBL] [Abstract][Full Text] [Related]
3. The antitumor agent ecteinascidin 743: characterization of its covalent DNA adducts and chemical stability.
Hurley LH; Zewail-Foote M
Adv Exp Med Biol; 2001; 500():289-99. PubMed ID: 11764956
[TBL] [Abstract][Full Text] [Related]
4. Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways.
Damia G; Silvestri S; Carrassa L; Filiberti L; Faircloth GT; Liberi G; Foiani M; D'Incalci M
Int J Cancer; 2001 May; 92(4):583-8. PubMed ID: 11304695
[TBL] [Abstract][Full Text] [Related]
5. Excision repair of adozelesin-N3 adenine adduct by 3-methyladenine-DNA glycosylases and UvrABC nuclease.
Jin SG; Choi JH; Ahn B; O'Connor TR; Mar W; Lee CS
Mol Cells; 2001 Feb; 11(1):41-7. PubMed ID: 11266119
[TBL] [Abstract][Full Text] [Related]
6. DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata.
Pommier Y; Kohlhagen G; Bailly C; Waring M; Mazumder A; Kohn KW
Biochemistry; 1996 Oct; 35(41):13303-9. PubMed ID: 8873596
[TBL] [Abstract][Full Text] [Related]
7. Ecteinascidin 743: a minor groove alkylator that bends DNA toward the major groove.
Zewail-Foote M; Hurley LH
J Med Chem; 1999 Jul; 42(14):2493-7. PubMed ID: 10411470
[TBL] [Abstract][Full Text] [Related]
8. Interaction of the UvrABC nuclease system with a DNA duplex containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE.
Zou Y; Liu TM; Geacintov NE; Van Houten B
Biochemistry; 1995 Oct; 34(41):13582-93. PubMed ID: 7577947
[TBL] [Abstract][Full Text] [Related]
9. Recognition and incision of gamma-radiation-induced cross-linked guanine-thymine tandem lesion G[8,5-Me]T by UvrABC nuclease.
Yang Z; Colis LC; Basu AK; Zou Y
Chem Res Toxicol; 2005 Sep; 18(9):1339-46. PubMed ID: 16167825
[TBL] [Abstract][Full Text] [Related]
10. Recognition and incision of Cr(III) ligand-conjugated DNA adducts by the nucleotide excision repair proteins UvrABC: importance of the Cr(III)-purine moiety in the enzymatic reaction.
Arakawa H; Tang MS
Chem Res Toxicol; 2008 Jun; 21(6):1284-9. PubMed ID: 18452313
[TBL] [Abstract][Full Text] [Related]
11. Differential incision of bulky carcinogen-DNA adducts by the UvrABC nuclease: comparison of incision rates and the interactions of Uvr subunits with lesions of different structures.
Hoare S; Zou Y; Purohit V; Krishnasamy R; Skorvaga M; Van Houten B; Geacintov NE; Basu AK
Biochemistry; 2000 Oct; 39(40):12252-61. PubMed ID: 11015204
[TBL] [Abstract][Full Text] [Related]
12. Trabectedin and its C subunit modified analogue PM01183 attenuate nucleotide excision repair and show activity toward platinum-resistant cells.
Soares DG; Machado MS; Rocca CJ; Poindessous V; Ouaret D; Sarasin A; Galmarini CM; Henriques JA; Escargueil AE; Larsen AK
Mol Cancer Ther; 2011 Aug; 10(8):1481-9. PubMed ID: 21622731
[TBL] [Abstract][Full Text] [Related]
13. Poisoning of human DNA topoisomerase I by ecteinascidin 743, an anticancer drug that selectively alkylates DNA in the minor groove.
Takebayashi Y; Pourquier P; Yoshida A; Kohlhagen G; Pommier Y
Proc Natl Acad Sci U S A; 1999 Jun; 96(13):7196-201. PubMed ID: 10377391
[TBL] [Abstract][Full Text] [Related]
14. Robust incision of Benoz[a]pyrene-7,8-dihyrodiol-9,10-epoxide-DNA adducts by a recombinant thermoresistant interspecies combination UvrABC endonuclease system.
Jiang GH; Skorvaga M; Croteau DL; Van Houten B; States JC
Biochemistry; 2006 Jun; 45(25):7834-43. PubMed ID: 16784235
[TBL] [Abstract][Full Text] [Related]
15. Sequence context- and temperature-dependent nucleotide excision repair of a benzo[a]pyrene diol epoxide-guanine DNA adduct catalyzed by thermophilic UvrABC proteins.
Ruan Q; Liu T; Kolbanovskiy A; Liu Y; Ren J; Skorvaga M; Zou Y; Lader J; Malkani B; Amin S; Van Houten B; Geacintov NE
Biochemistry; 2007 Jun; 46(23):7006-15. PubMed ID: 17506530
[TBL] [Abstract][Full Text] [Related]
16. Effects of DNA adduct structure and sequence context on strand opening of repair intermediates and incision by UvrABC nuclease.
Zou Y; Shell SM; Utzat CD; Luo C; Yang Z; Geacintov NE; Basu AK
Biochemistry; 2003 Nov; 42(43):12654-61. PubMed ID: 14580212
[TBL] [Abstract][Full Text] [Related]
17. Increased DNA binding specificity for antitumor ecteinascidin 743 through protein-DNA interactions?
García-Nieto R; Manzanares I; Cuevas C; Gago F
J Med Chem; 2000 Nov; 43(23):4367-9. PubMed ID: 11087561
[No Abstract] [Full Text] [Related]
18. Rate of incision of N-acetyl-2-aminofluorene and N-2-aminofluorene adducts by UvrABC nuclease is adduct- and sequence-specific: comparison of the rates of UvrABC nuclease incision and protein-DNA complex formation.
Mekhovich O; Tang Ms; Romano LJ
Biochemistry; 1998 Jan; 37(2):571-9. PubMed ID: 9425079
[TBL] [Abstract][Full Text] [Related]
19. Recognition and incision of site-specifically modified C8 guanine adducts formed by 2-aminofluorene, N-acetyl-2-aminofluorene and 1-nitropyrene by UvrABC nuclease.
Luo C; Krishnasamy R; Basu AK; Zou Y
Nucleic Acids Res; 2000 Oct; 28(19):3719-24. PubMed ID: 11000263
[TBL] [Abstract][Full Text] [Related]
20. Ecteinascidin 743: a novel anticancer drug with a unique mechanism of action.
Aune GJ; Furuta T; Pommier Y
Anticancer Drugs; 2002 Jul; 13(6):545-55. PubMed ID: 12172500
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
