161 related articles for article (PubMed ID: 11733074)
1. Induction of lacI mutations in Big Blue Rat-2 cells treated with 1-(2-hydroxyethyl)-1-nitrosourea: a model system for the analysis of mutagenic potential of the hydroxyethyl adducts produced by 1,3-bis (2-chloroethyl)-1-nitrosourea.
Sprung CN; Wang YP; Miller DL; Giannini DD; Dhananjaya N; Bodell WJ
Mutat Res; 2001 Dec; 484(1-2):77-86. PubMed ID: 11733074
[TBL] [Abstract][Full Text] [Related]
2. DNA alkylation products formed by 1-(2-chloroethyl)-1-nitrosourea as molecular dosimeters of therapeutic response.
Bodell WJ
J Neurooncol; 2009 Feb; 91(3):257-64. PubMed ID: 18979209
[TBL] [Abstract][Full Text] [Related]
3. 1,3-butadiene: cancer, mutations, and adducts. Part II: Roles of two metabolites of 1,3-butadiene in mediating its in vivo genotoxicity.
Recio L; Saranko CJ; Steen AM
Res Rep Health Eff Inst; 2000 Mar; (92):49-87; discussion 141-9. PubMed ID: 10925839
[TBL] [Abstract][Full Text] [Related]
4. Spontaneous and ethylnitrosourea-induced mutation fixation and molecular spectra at the lacI transgene in the Big Blue rat-2 embryo cell line.
Zimmer DM; Zhang XB; Harbach PR; Mayo JK; Aaron CS
Environ Mol Mutagen; 1996; 28(4):325-33. PubMed ID: 8991060
[TBL] [Abstract][Full Text] [Related]
5. Mutagenic response of the endogenous hprt gene and lacI transgene in benzo[a]pyrene-treated Big Blue B6C3F1 mice.
Skopek TR; Kort KL; Marino DR; Mittal LV; Umbenhauer DR; Laws GM; Adams SP
Environ Mol Mutagen; 1996; 28(4):376-84. PubMed ID: 8991066
[TBL] [Abstract][Full Text] [Related]
6. Levels and distribution of BCNU in GBM tumors following intratumoral injection of DTI-015 (BCNU-ethanol).
Bodell WJ; Bodell AP; Giannini DD
Neuro Oncol; 2007 Jan; 9(1):12-9. PubMed ID: 17018699
[TBL] [Abstract][Full Text] [Related]
7. A more efficient Big Blue protocol improves transgene rescue and accuracy in a adduct and mutation measurement.
Bielas JH
Mutat Res; 2002 Jul; 518(2):107-12. PubMed ID: 12113761
[TBL] [Abstract][Full Text] [Related]
8. Spontaneous and ENU-induced mutation spectra at the cII locus in Big Blue Rat2 embryonic fibroblasts.
Watson DE; Cunningham ML; Tindall KR
Mutagenesis; 1998 Sep; 13(5):487-97. PubMed ID: 9800194
[TBL] [Abstract][Full Text] [Related]
9. Detection of N7-(2-hydroxyethyl)guanine adducts in DNA and 9L cells treated with 1-(2-chloroethyl)-1-nitrosourea.
Ye Q; Bodell WJ
J Chromatogr B Biomed Sci Appl; 1997 Jun; 694(1):65-70. PubMed ID: 9234849
[TBL] [Abstract][Full Text] [Related]
10. Repair of DNA alkylation products formed in 9L cell lines treated with 1-(2-chloroethyl)-1-nitrosourea.
Bodell WJ
Mutat Res; 2003 Jan; 522(1-2):85-92. PubMed ID: 12517414
[TBL] [Abstract][Full Text] [Related]
11. Marked differences in the role of O6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate, N-(2-hydroxyethyl)-N-nitrosourea, or N-ethyl-N-nitrosourea.
Jansen JG; Vrieling H; van Teijlingen CM; Mohn GR; Tates AD; van Zeeland AA
Cancer Res; 1995 May; 55(9):1875-82. PubMed ID: 7728755
[TBL] [Abstract][Full Text] [Related]
12. Mutation spectrum of 4-nitroquinoline N-oxide in the lacI transgenic Big Blue Rat2 cell line.
Ryu J; Youn J; Kim Y; Kwon O; Song Y; Kim H; Cho K; Chang I
Mutat Res; 1999 Sep; 445(1):127-35. PubMed ID: 10521698
[TBL] [Abstract][Full Text] [Related]
13. Comparison of mutant frequencies and types of mutations induced by thiotepa in the endogenous Hprt gene and transgenic lacI gene of Big Blue rats.
Chen T; Aidoo A; Manjanatha MG; Mittelstaedt RA; Shelton SD; Lyn-Cook LE; Casciano DA; Heflich RH
Mutat Res; 1998 Jul; 403(1-2):199-214. PubMed ID: 9726020
[TBL] [Abstract][Full Text] [Related]
14. Effects of O (6)-alkylguanine-DNA alkyltransferase deficiency in Escherichia coli as the host for the detection of mutations in lacI transgenic mice.
Sui H; Suzuki M; Yamada M; Hara T; Kawakami K; Shibuya T; Nohmi T; Sofuni T
Environ Mol Mutagen; 1999; 34(2-3):221-6. PubMed ID: 10529748
[TBL] [Abstract][Full Text] [Related]
15. Species-specific differences in hepatic mutant frequency and mutational spectrum among lambda/lacI transgenic rats and mice following exposure to aflatoxin B1.
Dycaico MJ; Stuart GR; Tobal GM; de Boer JG; Glickman BW; Provost GS
Carcinogenesis; 1996 Nov; 17(11):2347-56. PubMed ID: 8968048
[TBL] [Abstract][Full Text] [Related]
16. The butadiene metabolite, 1,2:3,4-diepoxybutane, induces micronuclei but is only weakly mutagenic at lacI in the Big Blue Rat2 lacI transgenic cell line.
Saranko CJ; Recio L
Environ Mol Mutagen; 1998; 31(1):32-40. PubMed ID: 9464313
[TBL] [Abstract][Full Text] [Related]
17. Mutational analysis of the liver, colon and kidney of Big Blue rats treated with 2-amino-3-methylimidazo[4,5-f]quinoline.
Bol SA; Horlbeck J; Markovic J; de Boer JG; Turesky RJ; Constable A
Carcinogenesis; 2000 Jan; 21(1):1-6. PubMed ID: 10607726
[TBL] [Abstract][Full Text] [Related]
18. Mice over-expressing human O6 alkylguanine-DNA alkyltransferase selectively reduce O6 methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea.
Allay E; Veigl M; Gerson SL
Oncogene; 1999 Jun; 18(25):3783-7. PubMed ID: 10391687
[TBL] [Abstract][Full Text] [Related]
19. A comparative study of in vivo mutation assays: analysis of hprt, lacI, cII/cI and as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue mice.
Monroe JJ; Kort KL; Miller JE; Marino DR; Skopek TR
Mutat Res; 1998 Oct; 421(1):121-36. PubMed ID: 9748534
[TBL] [Abstract][Full Text] [Related]
20. Gene- and tissue-specificity of mutation in Big Blue rats treated with the hepatocarcinogen N-hydroxy-2-acetylaminofluorene.
Chen T; Mittelstaedt RA; Shelton SD; Dass SB; Manjanatha MG; Casciano DA; Heflich RH
Environ Mol Mutagen; 2001; 37(3):203-14. PubMed ID: 11317338
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]