These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 11738576)

  • 1. 2'-O,4'-C-ethylene-bridged nucleic acids (ENA): highly nuclease-resistant and thermodynamically stable oligonucleotides for antisense drug.
    Morita K; Hasegawa C; Kaneko M; Tsutsumi S; Sone J; Ishikawa T; Imanishi T; Koizumi M
    Bioorg Med Chem Lett; 2002 Jan; 12(1):73-6. PubMed ID: 11738576
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) with nuclease-resistance and high affinity for RNA.
    Morita K; Hasegawa C; Kaneko M; Tsutsumi S; Sone J; Ishikawa T; Imanishi T; Koizumi M
    Nucleic Acids Res Suppl; 2001; (1):241-2. PubMed ID: 12836354
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and properties of 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) as effective antisense oligonucleotides.
    Morita K; Takagi M; Hasegawa C; Kaneko M; Tsutsumi S; Sone J; Ishikawa T; Imanishi T; Koizumi M
    Bioorg Med Chem; 2003 May; 11(10):2211-26. PubMed ID: 12713831
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) as next-generation antisense and antigene agents.
    Koizumi M
    Biol Pharm Bull; 2004 Apr; 27(4):453-6. PubMed ID: 15056846
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Conformationally constrained 2'-N,4'-C-ethylene-bridged thymidine (aza-ENA-T): synthesis, structure, physical, and biochemical studies of aza-ENA-T-modified oligonucleotides.
    Varghese OP; Barman J; Pathmasiri W; Plashkevych O; Honcharenko D; Chattopadhyaya J
    J Am Chem Soc; 2006 Nov; 128(47):15173-87. PubMed ID: 17117869
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Free-radical ring closure to conformationally locked α-L-carba-LNAs and synthesis of their oligos: nuclease stability, target RNA specificity, and elicitation of RNase H.
    Li Q; Yuan F; Zhou C; Plashkevych O; Chattopadhyaya J
    J Org Chem; 2010 Sep; 75(18):6122-40. PubMed ID: 20738147
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ENA oligonucleotides as therapeutics.
    Koizumi M
    Curr Opin Mol Ther; 2006 Apr; 8(2):144-9. PubMed ID: 16610767
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2'-O,4'-C-methyleneoxymethylene bridged nucleic acids (2',4'-BNA(COC)).
    Hari Y; Kodama T; Imanishi T; Obika S
    Methods Mol Biol; 2011; 764():31-57. PubMed ID: 21748632
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of 2'-O-[2-[(N,N-dimethylamino)oxy]ethyl] modified nucleosides and oligonucleotides.
    Prakash TP; Kawasaki AM; Fraser AS; Vasquez G; Manoharan M
    J Org Chem; 2002 Jan; 67(2):357-69. PubMed ID: 11798305
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of ENA Nucleotides and ENA Oligonucleotides.
    Morita K; Koizumi M
    Curr Protoc Nucleic Acid Chem; 2018 Mar; 72(1):4.79.1-4.79.21. PubMed ID: 29927121
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and properties of a bridged nucleic acid with a perhydro-1,2-oxazin-3-one ring.
    Shrestha AR; Hari Y; Yahara A; Osawa T; Obika S
    J Org Chem; 2011 Dec; 76(24):9891-9. PubMed ID: 22059648
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Triazole- and Tetrazole-Bridged Nucleic Acids: Synthesis, Duplex Stability, Nuclease Resistance, and in Vitro and in Vivo Antisense Potency.
    Mitsuoka Y; Yamamoto T; Kugimiya A; Waki R; Wada F; Tahara S; Sawamura M; Noda M; Fujimura Y; Kato Y; Hari Y; Obika S
    J Org Chem; 2017 Jan; 82(1):12-24. PubMed ID: 27936689
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of the RNase H cleavage kinetics and blood serum stability of the north-conformationally constrained and 2'-alkoxy modified oligonucleotides.
    Honcharenko D; Barman J; Varghese OP; Chattopadhyaya J
    Biochemistry; 2007 May; 46(19):5635-46. PubMed ID: 17411072
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and properties of 2'-O,4'-C-spirocyclopropylene bridged nucleic acid (scpBNA), an analogue of 2',4'-BNA/LNA bearing a cyclopropane ring.
    Yamaguchi T; Horiba M; Obika S
    Chem Commun (Camb); 2015 Jun; 51(47):9737-40. PubMed ID: 25985928
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and properties of 2',4'-BNA(NC): a bridged nucleic acid analogue.
    Rahman SM; Seki S; Obika S; Yoshikawa H; Miyashita K; Imanishi T
    J Am Chem Soc; 2008 Apr; 130(14):4886-96. PubMed ID: 18341342
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.
    Vester B; Wengel J
    Biochemistry; 2004 Oct; 43(42):13233-41. PubMed ID: 15491130
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of 2',4'-BNACOC bearing a purine nucleobase.
    Mitsuoka Y; Ohnishi R; Hari Y; Obika S; Imanishi T
    Nucleic Acids Symp Ser (Oxf); 2006; (50):13-4. PubMed ID: 17150793
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Five- and six-membered conformationally locked 2',4'-carbocyclic ribo-thymidines: synthesis, structure, and biochemical studies.
    Srivastava P; Barman J; Pathmasiri W; Plashkevych O; Wenska M; Chattopadhyaya J
    J Am Chem Soc; 2007 Jul; 129(26):8362-79. PubMed ID: 17552524
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enhancement of the inhibitory activity of oatp antisense oligonucleotides by incorporation of 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) without a loss of subtype selectivity.
    Takagi M; Morita K; Nakai D; Nakagomi R; Tokui T; Koizumi M
    Biochemistry; 2004 Apr; 43(15):4501-10. PubMed ID: 15078096
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of a novel 2',5'-bridged nucleic acid with sugar conformation fixed to S-type by N-O linkage.
    Kodama T; Matsuo C; Ori H; Obika S; Miyashita K; Imanishi T
    Nucleic Acids Symp Ser (Oxf); 2007; (51):159-60. PubMed ID: 18029635
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.