BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

554 related articles for article (PubMed ID: 11740489)

  • 1. Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2.
    Hofmann TG; Möller A; Sirma H; Zentgraf H; Taya Y; Dröge W; Will H; Schmitz ML
    Nat Cell Biol; 2002 Jan; 4(1):1-10. PubMed ID: 11740489
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.
    D'Orazi G; Cecchinelli B; Bruno T; Manni I; Higashimoto Y; Saito S; Gostissa M; Coen S; Marchetti A; Del Sal G; Piaggio G; Fanciulli M; Appella E; Soddu S
    Nat Cell Biol; 2002 Jan; 4(1):11-9. PubMed ID: 11780126
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of the SUMO-interacting motif in HIPK2 targeting to the PML nuclear bodies and regulation of p53.
    Sung KS; Lee YA; Kim ET; Lee SR; Ahn JH; Choi CY
    Exp Cell Res; 2011 Apr; 317(7):1060-70. PubMed ID: 21192925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.
    Zhang Q; Yoshimatsu Y; Hildebrand J; Frisch SM; Goodman RH
    Cell; 2003 Oct; 115(2):177-86. PubMed ID: 14567915
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains.
    Möller A; Sirma H; Hofmann TG; Rueffer S; Klimczak E; Dröge W; Will H; Schmitz ML
    Cancer Res; 2003 Aug; 63(15):4310-4. PubMed ID: 12907596
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage.
    Di Stefano V; Soddu S; Sacchi A; D'Orazi G
    Oncogene; 2005 Aug; 24(35):5431-42. PubMed ID: 15897882
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage.
    Reuven N; Adler J; Porat Z; Polonio-Vallon T; Hofmann TG; Shaul Y
    J Biol Chem; 2015 Jul; 290(27):16478-88. PubMed ID: 25944899
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation.
    Rui Y; Xu Z; Lin S; Li Q; Rui H; Luo W; Zhou HM; Cheung PY; Wu Z; Ye Z; Li P; Han J; Lin SC
    EMBO J; 2004 Nov; 23(23):4583-94. PubMed ID: 15526030
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage.
    Gresko E; Ritterhoff S; Sevilla-Perez J; Roscic A; Fröbius K; Kotevic I; Vichalkovski A; Hess D; Hemmings BA; Schmitz ML
    Oncogene; 2009 Feb; 28(5):698-708. PubMed ID: 19015637
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PML regulates p53 stability by sequestering Mdm2 to the nucleolus.
    Bernardi R; Scaglioni PP; Bergmann S; Horn HF; Vousden KH; Pandolfi PP
    Nat Cell Biol; 2004 Jul; 6(7):665-72. PubMed ID: 15195100
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AXIN is an essential co-activator for the promyelocytic leukemia protein in p53 activation.
    Li Q; He Y; Wei L; Wu X; Wu D; Lin S; Wang Z; Ye Z; Lin SC
    Oncogene; 2011 Mar; 30(10):1194-204. PubMed ID: 21057547
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Daxx cooperates with the Axin/HIPK2/p53 complex to induce cell death.
    Li Q; Wang X; Wu X; Rui Y; Liu W; Wang J; Wang X; Liou YC; Ye Z; Lin SC
    Cancer Res; 2007 Jan; 67(1):66-74. PubMed ID: 17210684
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis.
    Cecchinelli B; Lavra L; Rinaldo C; Iacovelli S; Gurtner A; Gasbarri A; Ulivieri A; Del Prete F; Trovato M; Piaggio G; Bartolazzi A; Soddu S; Sciacchitano S
    Mol Cell Biol; 2006 Jun; 26(12):4746-57. PubMed ID: 16738336
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Complex regulation of CREB-binding protein by homeodomain-interacting protein kinase 2.
    Kovács KA; Steinmann M; Halfon O; Magistretti PJ; Cardinaux JR
    Cell Signal; 2015 Nov; 27(11):2252-60. PubMed ID: 26247811
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hepatitis C virus core protein inhibits tumor suppressor protein promyelocytic leukemia function in human hepatoma cells.
    Herzer K; Weyer S; Krammer PH; Galle PR; Hofmann TG
    Cancer Res; 2005 Dec; 65(23):10830-7. PubMed ID: 16322229
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PML.
    Kim EJ; Park JS; Um SJ
    Nucleic Acids Res; 2003 Sep; 31(18):5356-67. PubMed ID: 12954772
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual roles for lysine 490 of promyelocytic leukemia protein in the transactivation of glucocorticoid receptor-interacting protein 1.
    Liu ST; Lu GY; Hsu YJ; Chang LC; Ho CL; Huang SM
    Biochim Biophys Acta; 2013 Aug; 1833(8):1799-810. PubMed ID: 23542129
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Knocking down PML impairs p53 signaling transduction pathway and suppresses irradiation induced apoptosis in breast carcinoma cell MCF-7.
    Bao-Lei T; Zhu-Zhong M; Yi S; Jun-Jie Q; Yan D; Hua L; Bin L; Guo-Wei Z; Zhi-Xian S
    J Cell Biochem; 2006 Feb; 97(3):561-71. PubMed ID: 16215989
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of nuclear bodies in apoptosis signalling.
    Krieghoff-Henning E; Hofmann TG
    Biochim Biophys Acta; 2008 Nov; 1783(11):2185-94. PubMed ID: 18680765
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling.
    Doucas V; Tini M; Egan DA; Evans RM
    Proc Natl Acad Sci U S A; 1999 Mar; 96(6):2627-32. PubMed ID: 10077561
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.