339 related articles for article (PubMed ID: 11741832)
1. TSC2 missense mutations inhibit tuberin phosphorylation and prevent formation of the tuberin-hamartin complex.
Nellist M; Verhaaf B; Goedbloed MA; Reuser AJ; van den Ouweland AM; Halley DJ
Hum Mol Genet; 2001 Dec; 10(25):2889-98. PubMed ID: 11741832
[TBL] [Abstract][Full Text] [Related]
2. Pathological mutations in TSC1 and TSC2 disrupt the interaction between hamartin and tuberin.
Hodges AK; Li S; Maynard J; Parry L; Braverman R; Cheadle JP; DeClue JE; Sampson JR
Hum Mol Genet; 2001 Dec; 10(25):2899-905. PubMed ID: 11741833
[TBL] [Abstract][Full Text] [Related]
3. Characterization of the cytosolic tuberin-hamartin complex. Tuberin is a cytosolic chaperone for hamartin.
Nellist M; van Slegtenhorst MA; Goedbloed M; van den Ouweland AM; Halley DJ; van der Sluijs P
J Biol Chem; 1999 Dec; 274(50):35647-52. PubMed ID: 10585443
[TBL] [Abstract][Full Text] [Related]
4. Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products.
van Slegtenhorst M; Nellist M; Nagelkerken B; Cheadle J; Snell R; van den Ouweland A; Reuser A; Sampson J; Halley D; van der Sluijs P
Hum Mol Genet; 1998 Jun; 7(6):1053-7. PubMed ID: 9580671
[TBL] [Abstract][Full Text] [Related]
5. Tuberin phosphorylation regulates its interaction with hamartin. Two proteins involved in tuberous sclerosis.
Aicher LD; Campbell JS; Yeung RS
J Biol Chem; 2001 Jun; 276(24):21017-21. PubMed ID: 11290735
[TBL] [Abstract][Full Text] [Related]
6. Regulation of tuberous sclerosis complex (TSC) function by 14-3-3 proteins.
Nellist M; Goedbloed MA; Halley DJ
Biochem Soc Trans; 2003 Jun; 31(Pt 3):587-91. PubMed ID: 12773161
[TBL] [Abstract][Full Text] [Related]
7. Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.
Tee AR; Manning BD; Roux PP; Cantley LC; Blenis J
Curr Biol; 2003 Aug; 13(15):1259-68. PubMed ID: 12906785
[TBL] [Abstract][Full Text] [Related]
8. Evidence for separable functions of tuberous sclerosis gene products in mammalian cell cycle regulation.
Miloloza A; Kubista M; Rosner M; Hengstschläger M
J Neuropathol Exp Neurol; 2002 Feb; 61(2):154-63. PubMed ID: 11853018
[TBL] [Abstract][Full Text] [Related]
9. Cell cycle-regulated phosphorylation of hamartin, the product of the tuberous sclerosis complex 1 gene, by cyclin-dependent kinase 1/cyclin B.
Astrinidis A; Senapedis W; Coleman TR; Henske EP
J Biol Chem; 2003 Dec; 278(51):51372-9. PubMed ID: 14551205
[TBL] [Abstract][Full Text] [Related]
10. The tuberin-hamartin complex negatively regulates beta-catenin signaling activity.
Mak BC; Takemaru K; Kenerson HL; Moon RT; Yeung RS
J Biol Chem; 2003 Feb; 278(8):5947-51. PubMed ID: 12511557
[TBL] [Abstract][Full Text] [Related]
11. Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.
Tee AR; Fingar DC; Manning BD; Kwiatkowski DJ; Cantley LC; Blenis J
Proc Natl Acad Sci U S A; 2002 Oct; 99(21):13571-6. PubMed ID: 12271141
[TBL] [Abstract][Full Text] [Related]
12. Loss of expression of tuberin and hamartin in tuberous sclerosis complex-associated but not in sporadic angiofibromas.
Fackler I; DeClue JE; Rust H; Vu PA; Kutzner H; Rütten A; Kaddu S; Sander CA; Volkenandt M; Johnson MW; Vinters HV; Wienecke R
J Cutan Pathol; 2003 Mar; 30(3):174-7. PubMed ID: 12641776
[TBL] [Abstract][Full Text] [Related]
13. Developmental expression of the tuberous sclerosis proteins tuberin and hamartin.
Murthy V; Stemmer-Rachamimov AO; Haddad LA; Roy JE; Cutone AN; Beauchamp RL; Smith N; Louis DN; Ramesh V
Acta Neuropathol; 2001 Mar; 101(3):202-10. PubMed ID: 11307618
[TBL] [Abstract][Full Text] [Related]
14. Distinct effects of single amino-acid changes to tuberin on the function of the tuberin-hamartin complex.
Nellist M; Sancak O; Goedbloed MA; Rohe C; van Netten D; Mayer K; Tucker-Williams A; van den Ouweland AM; Halley DJ
Eur J Hum Genet; 2005 Jan; 13(1):59-68. PubMed ID: 15483652
[TBL] [Abstract][Full Text] [Related]
15. Tuberin and hamartin are aberrantly expressed and linked to clinical outcome in human breast cancer: the role of promoter methylation of TSC genes.
Jiang WG; Sampson J; Martin TA; Lee-Jones L; Watkins G; Douglas-Jones A; Mokbel K; Mansel RE
Eur J Cancer; 2005 Jul; 41(11):1628-36. PubMed ID: 15951164
[TBL] [Abstract][Full Text] [Related]
16. The expression of hamartin, the product of the TSC1 gene, in normal human tissues and in TSC1- and TSC2-linked angiomyolipomas.
Plank TL; Logginidou H; Klein-Szanto A; Henske EP
Mod Pathol; 1999 May; 12(5):539-45. PubMed ID: 10349994
[TBL] [Abstract][Full Text] [Related]
17. Hamartin and tuberin interaction with the G2/M cyclin-dependent kinase CDK1 and its regulatory cyclins A and B.
Catania MG; Mischel PS; Vinters HV
J Neuropathol Exp Neurol; 2001 Jul; 60(7):711-23. PubMed ID: 11444800
[TBL] [Abstract][Full Text] [Related]
18. Tuberin and hamartin expression is reduced in the majority of subependymal giant cell astrocytomas in tuberous sclerosis complex consistent with a two-hit model of pathogenesis.
Jóźwiak S; Kwiatkowski D; Kotulska K; Larysz-Brysz M; Lewin-Kowalik J; Grajkowska W; Roszkowski M
J Child Neurol; 2004 Feb; 19(2):102-6. PubMed ID: 15072102
[TBL] [Abstract][Full Text] [Related]
19. Tumour suppressors hamartin and tuberin: intracellular signalling.
Krymskaya VP
Cell Signal; 2003 Aug; 15(8):729-39. PubMed ID: 12781866
[TBL] [Abstract][Full Text] [Related]
20. Identification and characterization of the interaction between tuberin and 14-3-3zeta.
Nellist M; Goedbloed MA; de Winter C; Verhaaf B; Jankie A; Reuser AJ; van den Ouweland AM; van der Sluijs P; Halley DJ
J Biol Chem; 2002 Oct; 277(42):39417-24. PubMed ID: 12176984
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
