BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

502 related articles for article (PubMed ID: 11741928)

  • 1. The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.
    Ficker E; Obejero-Paz CA; Zhao S; Brown AM
    J Biol Chem; 2002 Feb; 277(7):4989-98. PubMed ID: 11741928
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects.
    Zhou Z; Gong Q; January CT
    J Biol Chem; 1999 Oct; 274(44):31123-6. PubMed ID: 10531299
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C.
    Delisle BP; Anderson CL; Balijepalli RC; Anson BD; Kamp TJ; January CT
    J Biol Chem; 2003 Sep; 278(37):35749-54. PubMed ID: 12837749
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole.
    Zhou Z; Vorperian VR; Gong Q; Zhang S; January CT
    J Cardiovasc Electrophysiol; 1999 Jun; 10(6):836-43. PubMed ID: 10376921
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterisation of recombinant HERG K+ channel blockade by the Class Ia antiarrhythmic drug procainamide.
    Ridley JM; Milnes JT; Benest AV; Masters JD; Witchel HJ; Hancox JC
    Biochem Biophys Res Commun; 2003 Jun; 306(2):388-93. PubMed ID: 12804575
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency.
    Paulussen A; Raes A; Matthijs G; Snyders DJ; Cohen N; Aerssens J
    J Biol Chem; 2002 Dec; 277(50):48610-6. PubMed ID: 12354768
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-à-go-go-Related Gene.
    Roti EC; Myers CD; Ayers RA; Boatman DE; Delfosse SA; Chan EK; Ackerman MJ; January CT; Robertson GA
    J Biol Chem; 2002 Dec; 277(49):47779-85. PubMed ID: 12270925
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Defective human Ether-à-go-go-related gene trafficking linked to an endoplasmic reticulum retention signal in the C terminus.
    Kupershmidt S; Yang T; Chanthaphaychith S; Wang Z; Towbin JA; Roden DM
    J Biol Chem; 2002 Jul; 277(30):27442-8. PubMed ID: 12021266
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome.
    Ficker E; Dennis AT; Obejero-Paz CA; Castaldo P; Taglialatela M; Brown AM
    J Mol Cell Cardiol; 2000 Dec; 32(12):2327-37. PubMed ID: 11113008
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels.
    Chen J; Seebohm G; Sanguinetti MC
    Proc Natl Acad Sci U S A; 2002 Sep; 99(19):12461-6. PubMed ID: 12209010
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel characteristics of a misprocessed mutant HERG channel linked to hereditary long QT syndrome.
    Ficker E; Thomas D; Viswanathan PC; Dennis AT; Priori SG; Napolitano C; Memmi M; Wible BA; Kaufman ES; Iyengar S; Schwartz PJ; Rudy Y; Brown AM
    Am J Physiol Heart Circ Physiol; 2000 Oct; 279(4):H1748-56. PubMed ID: 11009462
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Blockage of the HERG human cardiac K+ channel by the gastrointestinal prokinetic agent cisapride.
    Mohammad S; Zhou Z; Gong Q; January CT
    Am J Physiol; 1997 Nov; 273(5):H2534-8. PubMed ID: 9374794
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel.
    Furutani M; Trudeau MC; Hagiwara N; Seki A; Gong Q; Zhou Z; Imamura S; Nagashima H; Kasanuki H; Takao A; Momma K; January CT; Robertson GA; Matsuoka R
    Circulation; 1999 May; 99(17):2290-4. PubMed ID: 10226095
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG.
    Ficker E; Dennis AT; Wang L; Brown AM
    Circ Res; 2003 Jun; 92(12):e87-100. PubMed ID: 12775586
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects.
    Zhou Z; Gong Q; Epstein ML; January CT
    J Biol Chem; 1998 Aug; 273(33):21061-6. PubMed ID: 9694858
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides.
    Spector PS; Curran ME; Keating MT; Sanguinetti MC
    Circ Res; 1996 Mar; 78(3):499-503. PubMed ID: 8593709
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): molecular mechanisms and restoration of intracellular protein processing.
    Thomas D; Kiehn J; Katus HA; Karle CA
    Cardiovasc Res; 2003 Nov; 60(2):235-41. PubMed ID: 14613852
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a COOH-terminal segment involved in maturation and stability of human ether-a-go-go-related gene potassium channels.
    Akhavan A; Atanasiu R; Shrier A
    J Biol Chem; 2003 Oct; 278(41):40105-12. PubMed ID: 12885765
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits.
    Gong Q; Anderson CL; January CT; Zhou Z
    Am J Physiol Heart Circ Physiol; 2004 Aug; 287(2):H652-8. PubMed ID: 15072950
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of the cyclic nucleotide binding domain of the HERG potassium channel and interactions with KCNE2.
    Cui J; Kagan A; Qin D; Mathew J; Melman YF; McDonald TV
    J Biol Chem; 2001 May; 276(20):17244-51. PubMed ID: 11278781
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.