BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

288 related articles for article (PubMed ID: 11746989)

  • 1. Frequent alterations in the Wnt signaling pathway in colorectal cancer with microsatellite instability.
    Shimizu Y; Ikeda S; Fujimori M; Kodama S; Nakahara M; Okajima M; Asahara T
    Genes Chromosomes Cancer; 2002 Jan; 33(1):73-81. PubMed ID: 11746989
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Frequent alterations of the beta-catenin and TCF-4 genes, but not of the APC gene, in colon cancers with high-frequency microsatellite instability.
    Fukushima H; Yamamoto H; Itoh F; Horiuchi S; Min Y; Iku S; Imai K
    J Exp Clin Cancer Res; 2001 Dec; 20(4):553-9. PubMed ID: 11876551
    [TBL] [Abstract][Full Text] [Related]  

  • 3. APC and CTNNB1 mutations in a large series of sporadic colorectal carcinomas stratified by the microsatellite instability status.
    Løvig T; Meling GI; Diep CB; Thorstensen L; Norheim Andersen S; Lothe RA; Rognum TO
    Scand J Gastroenterol; 2002 Oct; 37(10):1184-93. PubMed ID: 12408524
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instability.
    Thorstensen L; Lind GE; Løvig T; Diep CB; Meling GI; Rognum TO; Lothe RA
    Neoplasia; 2005 Feb; 7(2):99-108. PubMed ID: 15802015
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Frequent activation of the beta-catenin-Tcf signaling pathway in nonfamilial colorectal carcinomas with microsatellite instability.
    Shitoh K; Furukawa T; Kojima M; Konishi F; Miyaki M; Tsukamoto T; Nagai H
    Genes Chromosomes Cancer; 2001 Jan; 30(1):32-7. PubMed ID: 11107173
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1.
    Satoh S; Daigo Y; Furukawa Y; Kato T; Miwa N; Nishiwaki T; Kawasoe T; Ishiguro H; Fujita M; Tokino T; Sasaki Y; Imaoka S; Murata M; Shimano T; Yamaoka Y; Nakamura Y
    Nat Genet; 2000 Mar; 24(3):245-50. PubMed ID: 10700176
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Colorectal cancer and genetic alterations in the Wnt pathway.
    Segditsas S; Tomlinson I
    Oncogene; 2006 Dec; 25(57):7531-7. PubMed ID: 17143297
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [beta-Catenine as a genomic target of high-grade microsatellite instability in colorectal cancer].
    Kölble K; Barthel B; Ullrich O; Pidde H; Döhring C; Rüschoff J; Schlag PM; Dietel M
    Verh Dtsch Ges Pathol; 2000; 84():182-6. PubMed ID: 11217439
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tumor formation by genetic mutations in the components of the Wnt signaling pathway.
    Kikuchi A
    Cancer Sci; 2003 Mar; 94(3):225-9. PubMed ID: 12824913
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Wnt/beta-catenin signaling.
    Akiyama T
    Cytokine Growth Factor Rev; 2000 Dec; 11(4):273-82. PubMed ID: 10959075
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Frequent frameshift mutations of the TCF-4 gene in colorectal cancers with microsatellite instability.
    Duval A; Gayet J; Zhou XP; Iacopetta B; Thomas G; Hamelin R
    Cancer Res; 1999 Sep; 59(17):4213-5. PubMed ID: 10485457
    [TBL] [Abstract][Full Text] [Related]  

  • 12. No evidence for involvement of beta-catenin and APC in urothelial carcinomas.
    Stoehr R; Krieg RC; Knuechel R; Hofstaedter F; Pilarsky C; Zaak D; Schmitt R; Hartmann A
    Int J Oncol; 2002 May; 20(5):905-11. PubMed ID: 11956582
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Relationship of vegetal cortical dorsal factors in the Xenopus egg with the Wnt/beta-catenin signaling pathway.
    Marikawa Y; Elinson RP
    Mech Dev; 1999 Dec; 89(1-2):93-102. PubMed ID: 10559484
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level.
    Nakamura T; Hamada F; Ishidate T; Anai K; Kawahara K; Toyoshima K; Akiyama T
    Genes Cells; 1998 Jun; 3(6):395-403. PubMed ID: 9734785
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aberrant localization of beta-catenin correlates with overexpression of its target gene in human papillary thyroid cancer.
    Ishigaki K; Namba H; Nakashima M; Nakayama T; Mitsutake N; Hayashi T; Maeda S; Ichinose M; Kanematsu T; Yamashita S
    J Clin Endocrinol Metab; 2002 Jul; 87(7):3433-40. PubMed ID: 12107263
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis.
    Kolligs FT; Bommer G; Göke B
    Digestion; 2002; 66(3):131-44. PubMed ID: 12481159
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular genetic alterations and clinical features in early-onset colorectal carcinomas and their role for the recognition of hereditary cancer syndromes.
    Losi L; Di Gregorio C; Pedroni M; Ponti G; Roncucci L; Scarselli A; Genuardi M; Baglioni S; Marino M; Rossi G; Benatti P; Maffei S; Menigatti M; Roncari B; Ponz de Leon M
    Am J Gastroenterol; 2005 Oct; 100(10):2280-7. PubMed ID: 16181381
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A gene marker panel covering the Wnt and the Ras-Raf-MEK-MAPK signalling pathways allows to detect gene mutations in 80% of early (UICC I) colon cancer stages in humans.
    Scholtka B; Schneider M; Melcher R; Katzenberger T; Friedrich D; Berghof-Jäger K; Scheppach W; Steinberg P
    Cancer Epidemiol; 2009 Aug; 33(2):123-9. PubMed ID: 19679059
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overexpression of Icat induces G(2) arrest and cell death in tumor cell mutants for adenomatous polyposis coli, beta-catenin, or Axin.
    Sekiya T; Nakamura T; Kazuki Y; Oshimura M; Kohu K; Tago K; Ohwada S; Akiyama T
    Cancer Res; 2002 Jun; 62(11):3322-6. PubMed ID: 12036951
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Colorectal cancers show distinct mutation spectra in members of the canonical WNT signaling pathway according to their anatomical location and type of genetic instability.
    Albuquerque C; Baltazar C; Filipe B; Penha F; Pereira T; Smits R; Cravo M; Lage P; Fidalgo P; Claro I; Rodrigues P; Veiga I; Ramos JS; Fonseca I; Leitão CN; Fodde R
    Genes Chromosomes Cancer; 2010 Aug; 49(8):746-59. PubMed ID: 20544848
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.