244 related articles for article (PubMed ID: 11747421)
1. Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.
Reeves CD; Murli S; Ashley GW; Piagentini M; Hutchinson CR; McDaniel R
Biochemistry; 2001 Dec; 40(51):15464-70. PubMed ID: 11747421
[TBL] [Abstract][Full Text] [Related]
2. Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units.
Lau J; Fu H; Cane DE; Khosla C
Biochemistry; 1999 Feb; 38(5):1643-51. PubMed ID: 9931032
[TBL] [Abstract][Full Text] [Related]
3. Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
Liou GF; Lau J; Cane DE; Khosla C
Biochemistry; 2003 Jan; 42(1):200-7. PubMed ID: 12515555
[TBL] [Abstract][Full Text] [Related]
4. Enhancing the modularity of the modular polyketide synthases: transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylase.
Kumar P; Koppisch AT; Cane DE; Khosla C
J Am Chem Soc; 2003 Nov; 125(47):14307-12. PubMed ID: 14624579
[TBL] [Abstract][Full Text] [Related]
5. A model of structure and catalysis for ketoreductase domains in modular polyketide synthases.
Reid R; Piagentini M; Rodriguez E; Ashley G; Viswanathan N; Carney J; Santi DV; Hutchinson CR; McDaniel R
Biochemistry; 2003 Jan; 42(1):72-9. PubMed ID: 12515540
[TBL] [Abstract][Full Text] [Related]
6. Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives.
Ruan X; Pereda A; Stassi DL; Zeidner D; Summers RG; Jackson M; Shivakumar A; Kakavas S; Staver MJ; Donadio S; Katz L
J Bacteriol; 1997 Oct; 179(20):6416-25. PubMed ID: 9335291
[TBL] [Abstract][Full Text] [Related]
7. Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules.
Hans M; Hornung A; Dziarnowski A; Cane DE; Khosla C
J Am Chem Soc; 2003 May; 125(18):5366-74. PubMed ID: 12720450
[TBL] [Abstract][Full Text] [Related]
8. Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei.
Tang L; Yoon YJ; Choi CY; Hutchinson CR
Gene; 1998 Aug; 216(2):255-65. PubMed ID: 9729415
[TBL] [Abstract][Full Text] [Related]
9. Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases.
Haydock SF; Aparicio JF; Molnár I; Schwecke T; Khaw LE; König A; Marsden AF; Galloway IS; Staunton J; Leadlay PF
FEBS Lett; 1995 Oct; 374(2):246-8. PubMed ID: 7589545
[TBL] [Abstract][Full Text] [Related]
10. Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases.
Yadav G; Gokhale RS; Mohanty D
J Mol Biol; 2003 Apr; 328(2):335-63. PubMed ID: 12691745
[TBL] [Abstract][Full Text] [Related]
11. Functional orientation of the acyltransferase domain in a module of the erythromycin polyketide synthase.
Gokhale RS; Lau J; Cane DE; Khosla C
Biochemistry; 1998 Feb; 37(8):2524-8. PubMed ID: 9485401
[TBL] [Abstract][Full Text] [Related]
12. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering.
Koryakina I; Kasey C; McArthur JB; Lowell AN; Chemler JA; Li S; Hansen DA; Sherman DH; Williams GJ
ACS Chem Biol; 2017 Jan; 12(1):114-123. PubMed ID: 28103677
[TBL] [Abstract][Full Text] [Related]
13. A new substrate specificity for acyl transferase domains of the ascomycin polyketide synthase in Streptomyces hygroscopicus.
Reeves CD; Chung LM; Liu Y; Xue Q; Carney JR; Revill WP; Katz L
J Biol Chem; 2002 Mar; 277(11):9155-9. PubMed ID: 11786554
[TBL] [Abstract][Full Text] [Related]
14. Chain initiation on the soraphen-producing modular polyketide synthase from Sorangium cellulosum.
Wilkinson CJ; Frost EJ; Staunton J; Leadlay PF
Chem Biol; 2001 Dec; 8(12):1197-208. PubMed ID: 11755398
[TBL] [Abstract][Full Text] [Related]
15. Analysis of the enzymatic domains in the modular portion of the coronafacic acid polyketide synthase.
Jiralerspong S; Rangaswamy V; Bender CL; Parry RJ
Gene; 2001 May; 270(1-2):191-200. PubMed ID: 11404016
[TBL] [Abstract][Full Text] [Related]
16. Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase.
Kalkreuter E; Bingham KS; Keeler AM; Lowell AN; Schmidt JJ; Sherman DH; Williams GJ
Nat Commun; 2021 Apr; 12(1):2193. PubMed ID: 33850151
[TBL] [Abstract][Full Text] [Related]
17. Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity.
Florova G; Kazanina G; Reynolds KA
Biochemistry; 2002 Aug; 41(33):10462-71. PubMed ID: 12173933
[TBL] [Abstract][Full Text] [Related]
18. Tolerance and specificity of recombinant 6-methylsalicyclic acid synthase.
Richardson MT; Pohl NL; Kealey JT; Khosla C
Metab Eng; 1999 Apr; 1(2):180-7. PubMed ID: 10935930
[TBL] [Abstract][Full Text] [Related]
19. Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin biosynthesis in Streptomyces noursei.
Brautaset T; Borgos SE; Sletta H; Ellingsen TE; Zotchev SB
J Biol Chem; 2003 Apr; 278(17):14913-9. PubMed ID: 12594224
[TBL] [Abstract][Full Text] [Related]
20. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
Dunn BJ; Watts KR; Robbins T; Cane DE; Khosla C
Biochemistry; 2014 Jun; 53(23):3796-806. PubMed ID: 24871074
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]