387 related articles for article (PubMed ID: 11747459)
1. Kinetic and mechanistic studies of penicillin-binding protein 2x from Streptococcus pneumoniae.
Thomas B; Wang Y; Stein RL
Biochemistry; 2001 Dec; 40(51):15811-23. PubMed ID: 11747459
[TBL] [Abstract][Full Text] [Related]
2. Neisseria gonorrhoeae penicillin-binding protein 3 exhibits exceptionally high carboxypeptidase and beta-lactam binding activities.
Stefanova ME; Tomberg J; Olesky M; Höltje JV; Gutheil WG; Nicholas RA
Biochemistry; 2003 Dec; 42(49):14614-25. PubMed ID: 14661974
[TBL] [Abstract][Full Text] [Related]
3. Trapping of an acyl-enzyme intermediate in a penicillin-binding protein (PBP)-catalyzed reaction.
Macheboeuf P; Lemaire D; Teller N; Martins Ados S; Luxen A; Dideberg O; Jamin M; Dessen A
J Mol Biol; 2008 Feb; 376(2):405-13. PubMed ID: 18155726
[TBL] [Abstract][Full Text] [Related]
4. Overexpression and enzymatic characterization of Neisseria gonorrhoeae penicillin-binding protein 4.
Stefanova ME; Tomberg J; Davies C; Nicholas RA; Gutheil WG
Eur J Biochem; 2004 Jan; 271(1):23-32. PubMed ID: 14686916
[TBL] [Abstract][Full Text] [Related]
5. Kinetics of beta-lactam interactions with penicillin-susceptible and -resistant penicillin-binding protein 2x proteins from Streptococcus pneumoniae. Involvement of acylation and deacylation in beta-lactam resistance.
Lu WP; Kincaid E; Sun Y; Bauer MD
J Biol Chem; 2001 Aug; 276(34):31494-501. PubMed ID: 11408478
[TBL] [Abstract][Full Text] [Related]
6. pH, inhibitor, and substrate specificity studies on Escherichia coli penicillin-binding protein 5.
Stefanova ME; Davies C; Nicholas RA; Gutheil WG
Biochim Biophys Acta; 2002 Jun; 1597(2):292-300. PubMed ID: 12044907
[TBL] [Abstract][Full Text] [Related]
7. Beta-secondary and solvent deuterium kinetic isotope effects on catalysis by the Streptomyces R61 DD-peptidase: comparisons with a structurally similar class C beta-lactamase.
Adediran SA; Pratt RF
Biochemistry; 1999 Feb; 38(5):1469-77. PubMed ID: 9931012
[TBL] [Abstract][Full Text] [Related]
8. Penicillin-binding protein 2x of Streptococcus pneumoniae: enzymic activities and interactions with beta-lactams.
Jamin M; Damblon C; Millier S; Hakenbeck R; Frère JM
Biochem J; 1993 Jun; 292 ( Pt 3)(Pt 3):735-41. PubMed ID: 8318005
[TBL] [Abstract][Full Text] [Related]
9. Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of beta-lactam antibiotics.
Alkema WB; de Vries E; Floris R; Janssen DB
Eur J Biochem; 2003 Sep; 270(18):3675-83. PubMed ID: 12950251
[TBL] [Abstract][Full Text] [Related]
10. Hydrogen bonding and protein perturbation in beta-lactam acyl-enzymes of Streptococcus pneumoniae penicillin-binding protein PBP2x.
Chittock RS; Ward S; Wilkinson AS; Caspers P; Mensch B; Page MG; Wharton CW
Biochem J; 1999 Feb; 338 ( Pt 1)(Pt 1):153-9. PubMed ID: 9931311
[TBL] [Abstract][Full Text] [Related]
11. Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins.
McDonough MA; Anderson JW; Silvaggi NR; Pratt RF; Knox JR; Kelly JA
J Mol Biol; 2002 Sep; 322(1):111-22. PubMed ID: 12215418
[TBL] [Abstract][Full Text] [Related]
12. Glycosyltransferase domain of penicillin-binding protein 2a from Streptococcus pneumoniae is membrane associated.
di Guilmi AM; Mouz N; Martin L; Hoskins J; Jaskunas SR; Dideberg O; Vernet T
J Bacteriol; 1999 May; 181(9):2773-81. PubMed ID: 10217767
[TBL] [Abstract][Full Text] [Related]
13. Crystal structure of Escherichia coli penicillin-binding protein 5 bound to a tripeptide boronic acid inhibitor: a role for Ser-110 in deacylation.
Nicola G; Peddi S; Stefanova M; Nicholas RA; Gutheil WG; Davies C
Biochemistry; 2005 Jun; 44(23):8207-17. PubMed ID: 15938610
[TBL] [Abstract][Full Text] [Related]
14. Mutations in the active site of penicillin-binding protein PBP2x from Streptococcus pneumoniae. Role in the specificity for beta-lactam antibiotics.
Mouz N; Di Guilmi AM; Gordon E; Hakenbeck R; Dideberg O; Vernet T
J Biol Chem; 1999 Jul; 274(27):19175-80. PubMed ID: 10383423
[TBL] [Abstract][Full Text] [Related]
15. Role of glutamate-268 in the catalytic mechanism of nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans.
Marchal S; Rahuel-Clermont S; Branlant G
Biochemistry; 2000 Mar; 39(12):3327-35. PubMed ID: 10727225
[TBL] [Abstract][Full Text] [Related]
16. Increase of the deacylation rate of PBP2x from Streptococcus pneumoniae by single point mutations mimicking the class A beta-lactamases.
Chesnel L; Zapun A; Mouz N; Dideberg O; Vernet T
Eur J Biochem; 2002 Mar; 269(6):1678-83. PubMed ID: 11895438
[TBL] [Abstract][Full Text] [Related]
17. Altering enzymatic activity: recruitment of carboxypeptidase activity into an RTEM beta-lactamase/penicillin-binding protein 5 chimera.
Chang YH; Labgold MR; Richards JH
Proc Natl Acad Sci U S A; 1990 Apr; 87(7):2823-7. PubMed ID: 2181451
[TBL] [Abstract][Full Text] [Related]
18. pKa, MM, and QM studies of mechanisms of beta-lactamases and penicillin-binding proteins: acylation step.
Massova I; Kollman PA
J Comput Chem; 2002 Dec; 23(16):1559-76. PubMed ID: 12395425
[TBL] [Abstract][Full Text] [Related]
19. Kinetic analysis of the action of tissue transglutaminase on peptide and protein substrates.
Case A; Stein RL
Biochemistry; 2003 Aug; 42(31):9466-81. PubMed ID: 12899634
[TBL] [Abstract][Full Text] [Related]
20. The bimodular G57-V577 polypeptide chain of the class B penicillin-binding protein 3 of Escherichia coli catalyzes peptide bond formation from thiolesters and does not catalyze glycan chain polymerization from the lipid II intermediate.
Adam M; Fraipont C; Rhazi N; Nguyen-Distèche M; Lakaye B; Frère JM; Devreese B; Van Beeumen J; van Heijenoort Y; van Heijenoort J; Ghuysen JM
J Bacteriol; 1997 Oct; 179(19):6005-9. PubMed ID: 9324244
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]