BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 11750083)

  • 1. Multidrug-resistance mdr1a/1b double knockout mice are more sensitive than wild type mice to acute arsenic toxicity, with higher arsenic accumulation in tissues.
    Liu J; Liu Y; Powell DA; Waalkes MP; Klaassen CD
    Toxicology; 2002 Jan; 170(1-2):55-62. PubMed ID: 11750083
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Toxicokinetic and genomic analysis of chronic arsenic exposure in multidrug-resistance mdr1a/1b(-/-) double knockout mice.
    Xie Y; Liu J; Liu Y; Klaassen CD; Waalkes MP
    Mol Cell Biochem; 2004 Jan; 255(1-2):11-8. PubMed ID: 14971641
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The pharmacological phenotype of combined multidrug-resistance mdr1a/1b- and mrp1-deficient mice.
    Johnson DR; Finch RA; Lin ZP; Zeiss CJ; Sartorelli AC
    Cancer Res; 2001 Feb; 61(4):1469-76. PubMed ID: 11245453
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The impact of pharmacologic and genetic knockout of P-glycoprotein on nelfinavir levels in the brain and other tissues in mice.
    Salama NN; Kelly EJ; Bui T; Ho RJ
    J Pharm Sci; 2005 Jun; 94(6):1216-25. PubMed ID: 15858856
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833.
    Mayer U; Wagenaar E; Dorobek B; Beijnen JH; Borst P; Schinkel AH
    J Clin Invest; 1997 Nov; 100(10):2430-6. PubMed ID: 9366556
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MDR1 transporter protects against paraquat-induced toxicity in human and mouse proximal tubule cells.
    Wen X; Gibson CJ; Yang I; Buckley B; Goedken MJ; Richardson JR; Aleksunes LM
    Toxicol Sci; 2014 Oct; 141(2):475-83. PubMed ID: 25015657
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential involvement of multidrug resistance-associated protein 1 and P-glycoprotein in tissue distribution and excretion of grepafloxacin in mice.
    Sasabe H; Kato Y; Suzuki T; Itose M; Miyamoto G; Sugiyama Y
    J Pharmacol Exp Ther; 2004 Aug; 310(2):648-55. PubMed ID: 15131241
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metallothionein-I/II null mice are more sensitive than wild-type mice to the hepatotoxic and nephrotoxic effects of chronic oral or injected inorganic arsenicals.
    Liu J; Liu Y; Goyer RA; Achanzar W; Waalkes MP
    Toxicol Sci; 2000 Jun; 55(2):460-7. PubMed ID: 10828279
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Realgar- and cinnabar-containing an-gong-niu-huang wan (AGNH) is much less acutely toxic than sodium arsenite and mercuric chloride.
    Lu YF; Yan JW; Wu Q; Shi JZ; Liu J; Shi JS
    Chem Biol Interact; 2011 Jan; 189(1-2):134-40. PubMed ID: 21094152
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The effect of breast cancer resistance protein and P-glycoprotein on the brain penetration of flavopiridol, imatinib mesylate (Gleevec), prazosin, and 2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid (PF-407288) in mice.
    Zhou L; Schmidt K; Nelson FR; Zelesky V; Troutman MD; Feng B
    Drug Metab Dispos; 2009 May; 37(5):946-55. PubMed ID: 19225039
    [TBL] [Abstract][Full Text] [Related]  

  • 11. P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387.
    Durmus S; Xu N; Sparidans RW; Wagenaar E; Beijnen JH; Schinkel AH
    Pharmacol Res; 2013 Oct; 76():9-16. PubMed ID: 23827160
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Distribution of arsenic species and its DNA damage in subchronic arsenite-exposed mice].
    Li H; Lin J; Li Y; Yan J; Li B; Zhang W; Dong Z; Chen C
    Wei Sheng Yan Jiu; 2013 Sep; 42(5):764-9, 776. PubMed ID: 24218882
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes.
    Schuetz EG; Umbenhauer DR; Yasuda K; Brimer C; Nguyen L; Relling MV; Schuetz JD; Schinkel AH
    Mol Pharmacol; 2000 Jan; 57(1):188-97. PubMed ID: 10617694
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Impact of P-glycoprotein and breast cancer resistance protein on the brain distribution of antiepileptic drugs in knockout mouse models.
    Nakanishi H; Yonezawa A; Matsubara K; Yano I
    Eur J Pharmacol; 2013 Jun; 710(1-3):20-8. PubMed ID: 23588114
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure.
    Smit JW; Huisman MT; van Tellingen O; Wiltshire HR; Schinkel AH
    J Clin Invest; 1999 Nov; 104(10):1441-7. PubMed ID: 10562306
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fumonisin toxicity in a transgenic mouse model lacking the mdr1a/1b P-glycoprotein genes.
    Sharma RP; Bhandari N; Tsunoda M; Riley RT; Voss KA; Meredith FI
    Environ Toxicol Pharmacol; 2000 Mar; 8(3):173-182. PubMed ID: 10925070
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics.
    Zhu L; Wu J; Zhao M; Song W; Qi X; Wang Y; Lu L; Liu Z
    Toxicol Appl Pharmacol; 2017 Apr; 320():32-39. PubMed ID: 28193520
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biliary transport of irinotecan and metabolites in normal and P-glycoprotein-deficient mice.
    Iyer L; Ramírez J; Shepard DR; Bingham CM; Hossfeld DK; Ratain MJ; Mayer U
    Cancer Chemother Pharmacol; 2002 Apr; 49(4):336-41. PubMed ID: 11914914
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Brain penetration of ivermectin and selamectin in mdr1a,b P-glycoprotein- and bcrp- deficient knockout mice.
    Geyer J; Gavrilova O; Petzinger E
    J Vet Pharmacol Ther; 2009 Feb; 32(1):87-96. PubMed ID: 19161460
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective regulation of multidrug resistance protein in vascular smooth muscle cells by the isoquinoline alkaloid coptisine.
    Suzuki H; Tanabe H; Mizukami H; Inoue M
    Biol Pharm Bull; 2010; 33(4):677-82. PubMed ID: 20410605
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.