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5. Concomitant inhibition of Janus kinase 3 and calcineurin-dependent signaling pathways synergistically prolongs the survival of rat heart allografts. Behbod F; Erwin-Cohen RA; Wang ME; Trawick BW; Qu X; Verani R; Kahan BD; Stepkowski SM; Kirken RA J Immunol; 2001 Mar; 166(6):3724-32. PubMed ID: 11238613 [TBL] [Abstract][Full Text] [Related]
6. JAK3 inhibition as a new concept for immune suppression. Borie DC; Si MS; Morris RE; Reitz BA; Changelian PS Curr Opin Investig Drugs; 2003 Nov; 4(11):1297-303. PubMed ID: 14758768 [TBL] [Abstract][Full Text] [Related]
7. Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor. Changelian PS; Flanagan ME; Ball DJ; Kent CR; Magnuson KS; Martin WH; Rizzuti BJ; Sawyer PS; Perry BD; Brissette WH; McCurdy SP; Kudlacz EM; Conklyn MJ; Elliott EA; Koslov ER; Fisher MB; Strelevitz TJ; Yoon K; Whipple DA; Sun J; Munchhof MJ; Doty JL; Casavant JM; Blumenkopf TA; Hines M; Brown MF; Lillie BM; Subramanyam C; Shang-Poa C; Milici AJ; Beckius GE; Moyer JD; Su C; Woodworth TG; Gaweco AS; Beals CR; Littman BH; Fisher DA; Smith JF; Zagouras P; Magna HA; Saltarelli MJ; Johnson KS; Nelms LF; Des Etages SG; Hayes LS; Kawabata TT; Finco-Kent D; Baker DL; Larson M; Si MS; Paniagua R; Higgins J; Holm B; Reitz B; Zhou YJ; Morris RE; O'Shea JJ; Borie DC Science; 2003 Oct; 302(5646):875-8. PubMed ID: 14593182 [TBL] [Abstract][Full Text] [Related]
8. Inhibition of Jak3 tyrosine kinase by PNU156804 blocks rat heart allograft rejection. Wang M; Kirken R; Behbod F; Erwin-Cohen R; Stepkowski SM; Kahan BD Transplant Proc; 2001; 33(1-2):201. PubMed ID: 11266779 [No Abstract] [Full Text] [Related]
9. Novel immunosuppression: R348, a JAK3- and Syk-inhibitor attenuates acute cardiac allograft rejection. Deuse T; Velotta JB; Hoyt G; Govaert JA; Taylor V; Masuda E; Herlaar E; Park G; Carroll D; Pelletier MP; Robbins RC; Schrepfer S Transplantation; 2008 Mar; 85(6):885-92. PubMed ID: 18360272 [TBL] [Abstract][Full Text] [Related]
10. JAK3 inhibition, a viable new modality of immunosuppression for solid organ transplants. Borie DC; O'Shea JJ; Changelian PS Trends Mol Med; 2004 Nov; 10(11):532-41. PubMed ID: 15519279 [TBL] [Abstract][Full Text] [Related]
11. Prevention of islet allograft rejection in diabetic mice by targeting Janus Kinase 3 with 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline (JANEX-1). Cetkovic-Cvrlje M; Dragt AL; Uckun FM Arzneimittelforschung; 2003; 53(9):648-54. PubMed ID: 14558439 [TBL] [Abstract][Full Text] [Related]
12. Targeting Janus kinase 3 in the treatment of leukemia and inflammatory diseases. Cetkovic-Cvrlje M; Uckun FM Arch Immunol Ther Exp (Warsz); 2004; 52(2):69-82. PubMed ID: 15179321 [TBL] [Abstract][Full Text] [Related]
13. The role of signals 1, 2, and 3 in induction of transplantation tolerance. Stepkowski SM; Nagy ZS; Kahan BD; Kirken RA Transplant Proc; 2001; 33(7-8):3831-2. PubMed ID: 11750632 [No Abstract] [Full Text] [Related]
14. Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1-transformed human T cells. Kirken RA; Erwin RA; Wang L; Wang Y; Rui H; Farrar WL J Immunol; 2000 Nov; 165(9):5097-104. PubMed ID: 11046040 [TBL] [Abstract][Full Text] [Related]
15. Suppression of early T-cell-receptor-triggered cellular activation by the Janus kinase 3 inhibitor WHI-P-154. Säemann MD; Zeyda M; Diakos C; Szekeres A; Böhmig GA; Kelemen P; Parolini O; Stockinger H; Prieschl EE; Stulnig TM; Baumruker T; Zlabinger GJ Transplantation; 2003 Jun; 75(11):1864-72. PubMed ID: 12811247 [TBL] [Abstract][Full Text] [Related]
16. STEALTH in transplantation tolerance. Hutchings A; Hubbard WJ; Thomas FT; Thomas JM Immunol Res; 2002; 26(1-3):143-52. PubMed ID: 12403353 [TBL] [Abstract][Full Text] [Related]
17. Immunosuppression by the JAK3 inhibitor CP-690,550 delays rejection and significantly prolongs kidney allograft survival in nonhuman primates. Borie DC; Changelian PS; Larson MJ; Si MS; Paniagua R; Higgins JP; Holm B; Campbell A; Lau M; Zhang S; Flores MG; Rousvoal G; Hawkins J; Ball DA; Kudlacz EM; Brissette WH; Elliott EA; Reitz BA; Morris RE Transplantation; 2005 Apr; 79(7):791-801. PubMed ID: 15818321 [TBL] [Abstract][Full Text] [Related]
18. Therapeutic potential of Janus kinase 3 (JAK3) inhibitors. Cetkovic-Cvrlje M; Tibbles HE Curr Pharm Des; 2004; 10(15):1767-84. PubMed ID: 15180539 [TBL] [Abstract][Full Text] [Related]
19. Is JAK3 a new drug target for immunomodulation-based therapies? Papageorgiou AC; Wikman LE Trends Pharmacol Sci; 2004 Nov; 25(11):558-62. PubMed ID: 15491777 [TBL] [Abstract][Full Text] [Related]
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