160 related articles for article (PubMed ID: 11752217)
1. Allosteric site on muscarinic acetylcholine receptors: a single amino acid in transmembrane region 7 is critical to the subtype selectivities of caracurine V derivatives and alkane-bisammonium ligands.
Buller S; Zlotos DP; Mohr K; Ellis J
Mol Pharmacol; 2002 Jan; 61(1):160-8. PubMed ID: 11752217
[TBL] [Abstract][Full Text] [Related]
2. Allosteric site on muscarinic acetylcholine receptors: identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-occupied receptors.
Voigtländer U; Jöhren K; Mohr M; Raasch A; Tränkle C; Buller S; Ellis J; Höltje HD; Mohr K
Mol Pharmacol; 2003 Jul; 64(1):21-31. PubMed ID: 12815157
[TBL] [Abstract][Full Text] [Related]
3. Interactions of alcuronium, TMB-8, and other allosteric ligands with muscarinic acetylcholine receptors: studies with chimeric receptors.
Ellis J; Seidenberg M
Mol Pharmacol; 2000 Dec; 58(6):1451-60. PubMed ID: 11093785
[TBL] [Abstract][Full Text] [Related]
4. Site-directed mutagenesis reveals two epitopes involved in the subtype selectivity of the allosteric interactions of gallamine at muscarinic acetylcholine receptors.
Gnagey AL; Seidenberg M; Ellis J
Mol Pharmacol; 1999 Dec; 56(6):1245-53. PubMed ID: 10570052
[TBL] [Abstract][Full Text] [Related]
5. Critical amino acid residues of the common allosteric site on the M2 muscarinic acetylcholine receptor: more similarities than differences between the structurally divergent agents gallamine and bis(ammonio)alkane-type hexamethylene-bis-[dimethyl-(3-phthalimidopropyl)ammonium]dibromide.
Huang XP; Prilla S; Mohr K; Ellis J
Mol Pharmacol; 2005 Sep; 68(3):769-78. PubMed ID: 15937215
[TBL] [Abstract][Full Text] [Related]
6. Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors.
Jakubík J; Bacáková L; el-Fakahany EE; Tucek S
J Pharmacol Exp Ther; 1995 Sep; 274(3):1077-83. PubMed ID: 7562472
[TBL] [Abstract][Full Text] [Related]
7. Allosteric interactions with muscarinic acetylcholine receptors: complex role of the conserved tryptophan M2422Trp in a critical cluster of amino acids for baseline affinity, subtype selectivity, and cooperativity.
Prilla S; Schrobang J; Ellis J; Höltje HD; Mohr K
Mol Pharmacol; 2006 Jul; 70(1):181-93. PubMed ID: 16641315
[TBL] [Abstract][Full Text] [Related]
8. Structural basis of the subtype selectivity of muscarinic antagonists: a study with chimeric m2/m5 muscarinic receptors.
Wess J; Gdula D; Brann MR
Mol Pharmacol; 1992 Feb; 41(2):369-74. PubMed ID: 1538713
[TBL] [Abstract][Full Text] [Related]
9. Use of chimeric muscarinic receptors to investigate epitopes involved in allosteric interactions.
Ellis J; Seidenberg M; Brann MR
Mol Pharmacol; 1993 Sep; 44(3):583-8. PubMed ID: 7690450
[TBL] [Abstract][Full Text] [Related]
10. Bisquaternary caracurine V derivatives as allosteric modulators of ligand binding to M2 acetylcholine receptors.
Zlotos DP; Buller S; Tränkle C; Mohr K
Bioorg Med Chem Lett; 2000 Nov; 10(22):2529-32. PubMed ID: 11086722
[TBL] [Abstract][Full Text] [Related]
11. Changes of cooperativity between N-methylscopolamine and allosteric modulators alcuronium and gallamine induced by mutations of external loops of muscarinic M(3) receptors.
Krejcí A; Tucek S
Mol Pharmacol; 2001 Oct; 60(4):761-7. PubMed ID: 11562438
[TBL] [Abstract][Full Text] [Related]
12. Site-directed mutagenesis implicates a threonine residue in TM6 in the subtype selectivities of UH-AH 37 and pirenzepine at muscarinic receptors.
Ellis J; Seidenberg M
Pharmacology; 2000 Aug; 61(2):62-9. PubMed ID: 10940778
[TBL] [Abstract][Full Text] [Related]
13. Role of acidic amino acids in the allosteric modulation by gallamine of antagonist binding at the m2 muscarinic acetylcholine receptor.
Leppik RA; Miller RC; Eck M; Paquet JL
Mol Pharmacol; 1994 May; 45(5):983-90. PubMed ID: 8190113
[TBL] [Abstract][Full Text] [Related]
14. Muscarinic allosteric modulation: M2/M3 subtype selectivity of gallamine is independent of G-protein coupling specificity.
Tränkle C; Kostenis E; Mohr K
Naunyn Schmiedebergs Arch Pharmacol; 2001 Aug; 364(2):172-8. PubMed ID: 11534857
[TBL] [Abstract][Full Text] [Related]
15. Competitive and allosteric interactions of 6-chloro-5,10-dihydro-5-[(1-methyl-4-piperidinyl)acetyl]-11H-di benzo[b,e][1, 4]diazepine-11-one hydrochloride (UH-AH 37) at muscarinic receptors, via distinct epitopes.
Ellis J; Seidenberg M
Biochem Pharmacol; 1999 Jan; 57(2):181-6. PubMed ID: 9890566
[TBL] [Abstract][Full Text] [Related]
16. Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors.
Jakubík J; Bacáková L; El-Fakahany EE; Tucek S
Mol Pharmacol; 1997 Jul; 52(1):172-9. PubMed ID: 9224827
[TBL] [Abstract][Full Text] [Related]
17. Identification of a [3H]Ligand for the common allosteric site of muscarinic acetylcholine M2 receptors.
Tränkle C; Mies-Klomfass E; Cid MH; Holzgrabe U; Mohr K
Mol Pharmacol; 1998 Jul; 54(1):139-45. PubMed ID: 9658199
[TBL] [Abstract][Full Text] [Related]
18. Intramolecular interactions in muscarinic acetylcholine receptors studied with chimeric m2/m5 receptors.
Pittel Z; Wess J
Mol Pharmacol; 1994 Jan; 45(1):61-4. PubMed ID: 8302281
[TBL] [Abstract][Full Text] [Related]
19. Mutational disruption of a conserved disulfide bond in muscarinic acetylcholine receptors attenuates positive homotropic cooperativity between multiple allosteric sites and has subtype-dependent effects on the affinities of muscarinic allosteric ligands.
Huang XP; Ellis J
Mol Pharmacol; 2007 Mar; 71(3):759-68. PubMed ID: 17132687
[TBL] [Abstract][Full Text] [Related]
20. M2 Subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: Effect of chemical homo-dimerization on orthosteric (and allosteric?) binding.
Keller M; Tränkle C; She X; Pegoli A; Bernhardt G; Buschauer A; Read RW
Bioorg Med Chem; 2015 Jul; 23(14):3970-90. PubMed ID: 25650309
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]