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4. SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Laird AD; Vajkoczy P; Shawver LK; Thurnher A; Liang C; Mohammadi M; Schlessinger J; Ullrich A; Hubbard SR; Blake RA; Fong TA; Strawn LM; Sun L; Tang C; Hawtin R; Tang F; Shenoy N; Hirth KP; McMahon G; Cherrington Cancer Res; 2000 Aug; 60(15):4152-60. PubMed ID: 10945623 [TBL] [Abstract][Full Text] [Related]
5. Inhibition of vascular endothelial growth factor-associated tyrosine kinase activity with SU5416 blocks sprouting in the microvascular endothelial cell spheroid model of angiogenesis. Haspel HC; Scicli GM; McMahon G; Scicli AG Microvasc Res; 2002 May; 63(3):304-15. PubMed ID: 11969307 [TBL] [Abstract][Full Text] [Related]
6. The combination of the tyrosine kinase receptor inhibitor SU6668 with paclitaxel affects ascites formation and tumor spread in ovarian carcinoma xenografts growing orthotopically. Garofalo A; Naumova E; Manenti L; Ghilardi C; Ghisleni G; Caniatti M; Colombo T; Cherrington JM; Scanziani E; Nicoletti MI; Giavazzi R Clin Cancer Res; 2003 Aug; 9(9):3476-85. PubMed ID: 12960140 [TBL] [Abstract][Full Text] [Related]
7. Effect of angiogenesis inhibitors on oestrogen-mediated endometrial endothelial cell proliferation in the ovariectomized mouse. Heryanto B; Lipson KE; Rogers PA Reproduction; 2003 Mar; 125(3):337-46. PubMed ID: 12611597 [TBL] [Abstract][Full Text] [Related]
8. Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms. Shaheen RM; Tseng WW; Davis DW; Liu W; Reinmuth N; Vellagas R; Wieczorek AA; Ogura Y; McConkey DJ; Drazan KE; Bucana CD; McMahon G; Ellis LM Cancer Res; 2001 Feb; 61(4):1464-8. PubMed ID: 11245452 [TBL] [Abstract][Full Text] [Related]
9. Enhancing the therapeutic responsiveness of photodynamic therapy with the antiangiogenic agents SU5416 and SU6668 in murine nasopharyngeal carcinoma models. Zhou Q; Olivo M; Lye KY; Moore S; Sharma A; Chowbay B Cancer Chemother Pharmacol; 2005 Dec; 56(6):569-77. PubMed ID: 16001166 [TBL] [Abstract][Full Text] [Related]
10. Vascular endothelial growth factor in human colon cancer: biology and therapeutic implications. Ellis LM; Takahashi Y; Liu W; Shaheen RM Oncologist; 2000; 5 Suppl 1():11-5. PubMed ID: 10804085 [TBL] [Abstract][Full Text] [Related]
11. SU5416 and SU6668 attenuate the angiogenic effects of radiation-induced tumor cell growth factor production and amplify the direct anti-endothelial action of radiation in vitro. Abdollahi A; Lipson KE; Han X; Krempien R; Trinh T; Weber KJ; Hahnfeldt P; Hlatky L; Debus J; Howlett AR; Huber PE Cancer Res; 2003 Jul; 63(13):3755-63. PubMed ID: 12839971 [TBL] [Abstract][Full Text] [Related]
12. SU6668 inhibits Flk-1/KDR and PDGFRbeta in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice. Laird AD; Christensen JG; Li G; Carver J; Smith K; Xin X; Moss KG; Louie SG; Mendel DB; Cherrington JM FASEB J; 2002 May; 16(7):681-90. PubMed ID: 11978732 [TBL] [Abstract][Full Text] [Related]
13. A multitargeted receptor tyrosine kinase inhibitor, SU6668, does not affect the healing of cutaneous full-thickness incisional wounds in SKH-1 mice. Duan WR; Patyna S; Kuhlmann MA; Li S; Blomme EA J Invest Surg; 2006; 19(4):245-54. PubMed ID: 16835139 [TBL] [Abstract][Full Text] [Related]
15. The angiogenesis inhibitor SU5416 has long-lasting effects on vascular endothelial growth factor receptor phosphorylation and function. Mendel DB; Schreck RE; West DC; Li G; Strawn LM; Tanciongco SS; Vasile S; Shawver LK; Cherrington JM Clin Cancer Res; 2000 Dec; 6(12):4848-58. PubMed ID: 11156244 [TBL] [Abstract][Full Text] [Related]
16. The antiangiogenic protein kinase inhibitors SU5416 and SU6668 inhibit the SCF receptor (c-kit) in a human myeloid leukemia cell line and in acute myeloid leukemia blasts. Smolich BD; Yuen HA; West KA; Giles FJ; Albitar M; Cherrington JM Blood; 2001 Mar; 97(5):1413-21. PubMed ID: 11222388 [TBL] [Abstract][Full Text] [Related]
17. Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248. Potapova O; Laird AD; Nannini MA; Barone A; Li G; Moss KG; Cherrington JM; Mendel DB Mol Cancer Ther; 2006 May; 5(5):1280-9. PubMed ID: 16731761 [TBL] [Abstract][Full Text] [Related]
18. Inhibition of vascular endothelial growth factor (VEGF) as a novel approach for cancer therapy. Wood JM Medicina (B Aires); 2000; 60 Suppl 2():41-7. PubMed ID: 11188930 [TBL] [Abstract][Full Text] [Related]
19. Measuring VEGF-Flk-1 activity and consequences of VEGF-Flk-1 targeting in vivo using intravital microscopy: clinical applications. Vajkoczy P; Thurnher A; Hirth KP; Schilling L; Schmiedek P; Ullrich A; Menger MD Oncologist; 2000; 5 Suppl 1():16-9. PubMed ID: 10804086 [TBL] [Abstract][Full Text] [Related]
20. Pharmacodynamic analysis of target inhibition and endothelial cell death in tumors treated with the vascular endothelial growth factor receptor antagonists SU5416 or SU6668. Davis DW; Takamori R; Raut CP; Xiong HQ; Herbst RS; Stadler WM; Heymach JV; Demetri GD; Rashid A; Shen Y; Wen S; Abbruzzese JL; McConkey DJ Clin Cancer Res; 2005 Jan; 11(2 Pt 1):678-89. PubMed ID: 15701856 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]