337 related articles for article (PubMed ID: 11756188)
1. Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.
Konopleva M; Tsao T; Ruvolo P; Stiouf I; Estrov Z; Leysath CE; Zhao S; Harris D; Chang S; Jackson CE; Munsell M; Suh N; Gribble G; Honda T; May WS; Sporn MB; Andreeff M
Blood; 2002 Jan; 99(1):326-35. PubMed ID: 11756188
[TBL] [Abstract][Full Text] [Related]
2. Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.
Kim KB; Lotan R; Yue P; Sporn MB; Suh N; Gribble GW; Honda T; Wu GS; Hong WK; Sun SY
Mol Cancer Ther; 2002 Jan; 1(3):177-84. PubMed ID: 12467212
[TBL] [Abstract][Full Text] [Related]
3. The novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism.
Ito Y; Pandey P; Place A; Sporn MB; Gribble GW; Honda T; Kharbanda S; Kufe D
Cell Growth Differ; 2000 May; 11(5):261-7. PubMed ID: 10845427
[TBL] [Abstract][Full Text] [Related]
4. Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway.
Ryu K; Susa M; Choy E; Yang C; Hornicek FJ; Mankin HJ; Duan Z
BMC Cancer; 2010 May; 10():187. PubMed ID: 20459702
[TBL] [Abstract][Full Text] [Related]
5. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells.
Stadheim TA; Suh N; Ganju N; Sporn MB; Eastman A
J Biol Chem; 2002 May; 277(19):16448-55. PubMed ID: 11880365
[TBL] [Abstract][Full Text] [Related]
6. The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
Konopleva M; Tsao T; Estrov Z; Lee RM; Wang RY; Jackson CE; McQueen T; Monaco G; Munsell M; Belmont J; Kantarjian H; Sporn MB; Andreeff M
Cancer Res; 2004 Nov; 64(21):7927-35. PubMed ID: 15520199
[TBL] [Abstract][Full Text] [Related]
7. The novel triterpenoid CDDO-Me suppresses MAPK pathways and promotes p38 activation in acute myeloid leukemia cells.
Konopleva M; Contractor R; Kurinna SM; Chen W; Andreeff M; Ruvolo PP
Leukemia; 2005 Aug; 19(8):1350-4. PubMed ID: 15931262
[TBL] [Abstract][Full Text] [Related]
8. CDDO-me induces apoptosis and inhibits Akt, mTOR and NF-kappaB signaling proteins in prostate cancer cells.
Deeb D; Gao X; Dulchavsky SA; Gautam SC
Anticancer Res; 2007; 27(5A):3035-44. PubMed ID: 17970042
[TBL] [Abstract][Full Text] [Related]
9. Combining the FLT3 inhibitor PKC412 and the triterpenoid CDDO-Me synergistically induces apoptosis in acute myeloid leukemia with the internal tandem duplication mutation.
Ahmad R; Liu S; Weisberg E; Nelson E; Galinsky I; Meyer C; Kufe D; Kharbanda S; Stone R
Mol Cancer Res; 2010 Jul; 8(7):986-93. PubMed ID: 20571062
[TBL] [Abstract][Full Text] [Related]
10. c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.
Zou W; Liu X; Yue P; Zhou Z; Sporn MB; Lotan R; Khuri FR; Sun SY
Cancer Res; 2004 Oct; 64(20):7570-8. PubMed ID: 15492284
[TBL] [Abstract][Full Text] [Related]
11. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
Shishodia S; Sethi G; Konopleva M; Andreeff M; Aggarwal BB
Clin Cancer Res; 2006 Mar; 12(6):1828-38. PubMed ID: 16551868
[TBL] [Abstract][Full Text] [Related]
12. The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism.
Ito Y; Pandey P; Sporn MB; Datta R; Kharbanda S; Kufe D
Mol Pharmacol; 2001 May; 59(5):1094-9. PubMed ID: 11306692
[TBL] [Abstract][Full Text] [Related]
13. The novel triterpenoid CDDO and its derivatives induce apoptosis by disruption of intracellular redox balance.
Ikeda T; Sporn M; Honda T; Gribble GW; Kufe D
Cancer Res; 2003 Sep; 63(17):5551-8. PubMed ID: 14500394
[TBL] [Abstract][Full Text] [Related]
14. Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3.
Amarante-Mendes GP; Naekyung Kim C; Liu L; Huang Y; Perkins CL; Green DR; Bhalla K
Blood; 1998 Mar; 91(5):1700-5. PubMed ID: 9473236
[TBL] [Abstract][Full Text] [Related]
15. Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL.
Suh WS; Kim YS; Schimmer AD; Kitada S; Minden M; Andreeff M; Suh N; Sporn M; Reed JC
Leukemia; 2003 Nov; 17(11):2122-9. PubMed ID: 12931220
[TBL] [Abstract][Full Text] [Related]
16. Induction of redox imbalance and apoptosis in multiple myeloma cells by the novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid.
Ikeda T; Nakata Y; Kimura F; Sato K; Anderson K; Motoyoshi K; Sporn M; Kufe D
Mol Cancer Ther; 2004 Jan; 3(1):39-45. PubMed ID: 14749474
[TBL] [Abstract][Full Text] [Related]
17. Retinoid induced apoptosis in leukemia cells through a retinoic acid nuclear receptor-independent pathway.
Hsu CA; Rishi AK; Su-Li X; Gerald TM; Dawson MI; Schiffer C; Reichert U; Shroot B; Poirier GG; Fontana JA
Blood; 1997 Jun; 89(12):4470-9. PubMed ID: 9192771
[TBL] [Abstract][Full Text] [Related]
18. Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells.
Wang YY; Yang YX; Zhao R; Pan ST; Zhe H; He ZX; Duan W; Zhang X; Yang T; Qiu JX; Zhou SF
Drug Des Devel Ther; 2015; 9():993-1026. PubMed ID: 25733817
[TBL] [Abstract][Full Text] [Related]
19. Transforming growth factor-beta1 inhibits all-trans retinoic acid-induced apoptosis.
Soucek K; Pacherník J; Kubala L; Vondrácek J; Hofmanová J; Kozubík A
Leuk Res; 2006 May; 30(5):607-23. PubMed ID: 16242776
[TBL] [Abstract][Full Text] [Related]
20. Resistance of acute myeloid leukemic cells to the triterpenoid CDDO-Imidazolide is associated with low caspase-8 and FADD levels.
Riccioni R; Senese M; Diverio D; Riti V; Mariani G; Boe A; LoCoco F; Foà R; Peschle C; Sporn M; Testa U
Leuk Res; 2008 Aug; 32(8):1244-58. PubMed ID: 18304628
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]