These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 11756445)

  • 1. Biosynthetic studies of A2E, a major fluorophore of retinal pigment epithelial lipofuscin.
    Ben-Shabat S; Parish CA; Vollmer HR; Itagaki Y; Fishkin N; Nakanishi K; Sparrow JR
    J Biol Chem; 2002 Mar; 277(9):7183-90. PubMed ID: 11756445
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane.
    Liu J; Itagaki Y; Ben-Shabat S; Nakanishi K; Sparrow JR
    J Biol Chem; 2000 Sep; 275(38):29354-60. PubMed ID: 10887199
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Immunochemical recognition of A2E, a pigment in the lipofuscin of retinal pigment epithelial cells.
    Abeywickrama C; Matsuda H; Jockusch S; Zhou J; Jang YP; Chen BX; Itagaki Y; Erlanger BF; Nakanishi K; Turro NJ; Sparrow JR
    Proc Natl Acad Sci U S A; 2007 Sep; 104(37):14610-5. PubMed ID: 17804788
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin.
    Kim SR; Nakanishi K; Itagaki Y; Sparrow JR
    Exp Eye Res; 2006 May; 82(5):828-39. PubMed ID: 16364293
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of peroxy-A2E and furan-A2E photooxidation products and detection in human and mouse retinal pigment epithelial cell lipofuscin.
    Jang YP; Matsuda H; Itagaki Y; Nakanishi K; Sparrow JR
    J Biol Chem; 2005 Dec; 280(48):39732-9. PubMed ID: 16186115
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of native retinal fluorophores involved in biosynthesis of A2E and lipofuscin-associated retinopathies.
    Bui TV; Han Y; Radu RA; Travis GH; Mata NL
    J Biol Chem; 2006 Jun; 281(26):18112-9. PubMed ID: 16638746
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A2E, a pigment of RPE lipofuscin, is generated from the precursor, A2PE by a lysosomal enzyme activity.
    Sparrow JR; Kim SR; Cuervo AM; Bandhyopadhyayand U
    Adv Exp Med Biol; 2008; 613():393-8. PubMed ID: 18188969
    [No Abstract]   [Full Text] [Related]  

  • 8. Characterization of dihydro-A2PE: an intermediate in the A2E biosynthetic pathway.
    Kim SR; He J; Yanase E; Jang YP; Berova N; Sparrow JR; Nakanishi K
    Biochemistry; 2007 Sep; 46(35):10122-9. PubMed ID: 17685561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal.
    Boyer NP; Higbee D; Currin MB; Blakeley LR; Chen C; Ablonczy Z; Crouch RK; Koutalos Y
    J Biol Chem; 2012 Jun; 287(26):22276-86. PubMed ID: 22570475
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A2E, a byproduct of the visual cycle.
    Sparrow JR; Fishkin N; Zhou J; Cai B; Jang YP; Krane S; Itagaki Y; Nakanishi K
    Vision Res; 2003 Dec; 43(28):2983-90. PubMed ID: 14611934
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Experimental approaches to the study of A2E, a bisretinoid lipofuscin chromophore of retinal pigment epithelium.
    Sparrow JR; Kim SR; Wu Y
    Methods Mol Biol; 2010; 652():315-27. PubMed ID: 20552437
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Preparative and biosynthetic insights into pdA2E and isopdA2E, retinal-derived fluorophores of retinal pigment epithelial lipofuscin.
    Zhao J; Yao K; Jin Q; Jiang K; Chen J; Liu Z; Li J; Wu Y
    Invest Ophthalmol Vis Sci; 2014 Nov; 55(12):8241-50. PubMed ID: 25414195
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease.
    Wu Y; Fishkin NE; Pande A; Pande J; Sparrow JR
    J Biol Chem; 2009 Jul; 284(30):20155-66. PubMed ID: 19478335
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Relative Contributions of All-Trans and 11-Cis Retinal to Formation of Lipofuscin and A2E Accumulating in Mouse Retinal Pigment Epithelium.
    Boyer NP; Thompson DA; Koutalos Y
    Invest Ophthalmol Vis Sci; 2021 Feb; 62(2):1. PubMed ID: 33523199
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of a novel lipofuscin pigment (iisoA2E) in retina and its effects in the retinal pigment epithelial cells.
    Li J; Yao K; Yu X; Dong X; Gan L; Luo C; Wu Y
    J Biol Chem; 2013 Dec; 288(50):35671-82. PubMed ID: 24169698
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model.
    Kim SR; Jang YP; Jockusch S; Fishkin NE; Turro NJ; Sparrow JR
    Proc Natl Acad Sci U S A; 2007 Dec; 104(49):19273-8. PubMed ID: 18048333
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Observation of A2E oxidation products in human retinal lipofuscin.
    Avalle LB; Wang Z; Dillon JP; Gaillard ER
    Exp Eye Res; 2004 Apr; 78(4):895-8. PubMed ID: 15037123
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A2E, a pigment of the lipofuscin of retinal pigment epithelial cells, is an endogenous ligand for retinoic acid receptor.
    Iriyama A; Fujiki R; Inoue Y; Takahashi H; Tamaki Y; Takezawa S; Takeyama K; Jang WD; Kato S; Yanagi Y
    J Biol Chem; 2008 May; 283(18):11947-53. PubMed ID: 18326047
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A2E: a component of ocular lipofuscin.
    Lamb LE; Simon JD
    Photochem Photobiol; 2004 Feb; 79(2):127-36. PubMed ID: 15068025
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium.
    Finnemann SC; Leung LW; Rodriguez-Boulan E
    Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3842-7. PubMed ID: 11904436
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.