These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
100 related articles for article (PubMed ID: 11764967)
1. Triazolam substrate inhibition: evidence of competition for heme-bound reactive oxygen within the CYP3A4 active site. Schrag ML; Wienkers LC Adv Exp Med Biol; 2001; 500():347-50. PubMed ID: 11764967 [No Abstract] [Full Text] [Related]
2. Triazolam substrate inhibition: evidence of competition for heme-bound reactive oxygen within the CYP3A4 active site. Schrag ML; Wienkers LC Drug Metab Dispos; 2001 Jan; 29(1):70-5. PubMed ID: 11124232 [TBL] [Abstract][Full Text] [Related]
3. Covalent alteration of the CYP3A4 active site: evidence for multiple substrate binding domains. Schrag ML; Wienkers LC Arch Biochem Biophys; 2001 Jul; 391(1):49-55. PubMed ID: 11414684 [TBL] [Abstract][Full Text] [Related]
4. Kinetics of testosterone 6beta-hydroxylation in the reconstituted system with similar ratios of purified CYP3A4, NADPH-cytochrome p450 oxidoreductase and cytochrome B5 to human liver microsomes. Taguchi M; Imaoka S; Yoshii K; Kobayashi K; Hosokawa M; Shimada N; Funae Y; Chiba K Res Commun Mol Pathol Pharmacol; 2001 Jul; 109(1-2):53-63. PubMed ID: 11458985 [TBL] [Abstract][Full Text] [Related]
5. Molecular characterization of specifically active recombinant fused enzymes consisting of CYP3A4, NADPH-cytochrome P450 oxidoreductase, and cytochrome b5. Inui H; Maeda A; Ohkawa H Biochemistry; 2007 Sep; 46(35):10213-21. PubMed ID: 17691855 [TBL] [Abstract][Full Text] [Related]
6. Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b5 in yeast. Hayashi K; Sakaki T; Kominami S; Inouye K; Yabusaki Y Arch Biochem Biophys; 2000 Sep; 381(1):164-70. PubMed ID: 11019832 [TBL] [Abstract][Full Text] [Related]
7. In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5. Patki KC; Von Moltke LL; Greenblatt DJ Drug Metab Dispos; 2003 Jul; 31(7):938-44. PubMed ID: 12814972 [TBL] [Abstract][Full Text] [Related]
8. N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine (DPPE) a chemopotentiating and cytoprotective agent in clinical trials: interaction with histamine at cytochrome P450 3A4 and other isozymes that metabolize antineoplastic drugs. Brandes LJ; Queen GM; LaBella FS Cancer Chemother Pharmacol; 2000; 45(4):298-304. PubMed ID: 10755318 [TBL] [Abstract][Full Text] [Related]
9. Effects of human cytochrome b5 on CYP3A4 activity and stability in vivo. Voice MW; Zhang Y; Wolf CR; Burchell B; Friedberg T Arch Biochem Biophys; 1999 Jun; 366(1):116-24. PubMed ID: 10334871 [TBL] [Abstract][Full Text] [Related]
10. [Activity of liver monooxygenase system in rats with low and high resistance to hypoxia]. Sharapov VI; Grek OR Biull Eksp Biol Med; 1996 Sep; 122(9):291-4. PubMed ID: 8974483 [No Abstract] [Full Text] [Related]
11. The effects of cytochrome b5, NADPH-P450 reductase, and lipid on the rate of 6 beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein. Shet MS; Faulkner KM; Holmans PL; Fisher CW; Estabrook RW Arch Biochem Biophys; 1995 Apr; 318(2):314-21. PubMed ID: 7733659 [TBL] [Abstract][Full Text] [Related]
12. Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam. van Waterschoot RA; Rooswinkel RW; Sparidans RW; van Herwaarden AE; Beijnen JH; Schinkel AH Drug Metab Dispos; 2009 Dec; 37(12):2305-13. PubMed ID: 19752211 [TBL] [Abstract][Full Text] [Related]
13. Benzene metabolism by two purified, reconstituted rat hepatic mixed function oxidase systems. Chepiga TA; Yang CS; Snyder R Adv Exp Med Biol; 1991; 283():261-5. PubMed ID: 2068993 [No Abstract] [Full Text] [Related]
14. [Activity of key enzymes of heme synthesis and degradation and contents of cytochromes b5 and P-450 in rat liver]. Kaliman PA; Padalko VI Biokhimiia; 1981 Aug; 46(8):1482-7. PubMed ID: 6895039 [TBL] [Abstract][Full Text] [Related]
15. Approach to predict the contribution of cytochrome P450 enzymes to drug metabolism in the early drug-discovery stage: the effect of the expression of cytochrome b(5) with recombinant P450 enzymes. Emoto C; Iwasaki K Xenobiotica; 2007 Sep; 37(9):986-99. PubMed ID: 17896325 [TBL] [Abstract][Full Text] [Related]
16. Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivo. Henderson CJ; McLaughlin LA; Scheer N; Stanley LA; Wolf CR Mol Pharmacol; 2015 Apr; 87(4):733-9. PubMed ID: 25657337 [TBL] [Abstract][Full Text] [Related]
17. Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen. Koenigs LL; Peter RM; Thompson SJ; Rettie AE; Trager WF Drug Metab Dispos; 1997 Dec; 25(12):1407-15. PubMed ID: 9394031 [TBL] [Abstract][Full Text] [Related]
18. Theoretical calculation of triazolam hydroxylation and endogenous steroid inhibition in the active site of CYP3A4. Torimoto N; Ishii I; Hata M; Kobayashi Y; Nakamura H; Ariyoshi N; Kitada M Biochim Biophys Acta; 2007 Feb; 1774(2):223-32. PubMed ID: 17204458 [TBL] [Abstract][Full Text] [Related]
19. Enhancement of cytochrome P-450 3A4 catalytic activities by cytochrome b(5) in bacterial membranes. Yamazaki H; Nakajima M; Nakamura M; Asahi S; Shimada N; Gillam EM; Guengerich FP; Shimada T; Yokoi T Drug Metab Dispos; 1999 Sep; 27(9):999-1004. PubMed ID: 10460798 [TBL] [Abstract][Full Text] [Related]
20. The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate. Loughran PA; Roman LJ; Miller RT; Masters BS Arch Biochem Biophys; 2001 Jan; 385(2):311-21. PubMed ID: 11368012 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]