BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

282 related articles for article (PubMed ID: 11767949)

  • 1. Osmolytes as modulators of conformational changes in serpins.
    Chow MK; Devlin GL; Bottomley SP
    Biol Chem; 2001 Nov; 382(11):1593-9. PubMed ID: 11767949
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prevention of polymerization of M and Z alpha1-Antitrypsin (alpha1-AT) with trimethylamine N-oxide. Implications for the treatment of alpha1-at deficiency.
    Devlin GL; Parfrey H; Tew DJ; Lomas DA; Bottomley SP
    Am J Respir Cell Mol Biol; 2001 Jun; 24(6):727-32. PubMed ID: 11415938
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Singular efficacy of trimethylamine N-oxide to counter protein destabilization in ice.
    Strambini GB; Gonnelli M
    Biochemistry; 2008 Mar; 47(11):3322-31. PubMed ID: 18293933
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Different conformational changes within the F-helix occur during serpin folding, polymerization, and proteinase inhibition.
    Cabrita LD; Dai W; Bottomley SP
    Biochemistry; 2004 Aug; 43(30):9834-9. PubMed ID: 15274637
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetic instability of the serpin Z alpha1-antitrypsin promotes aggregation.
    Knaupp AS; Levina V; Robertson AL; Pearce MC; Bottomley SP
    J Mol Biol; 2010 Feb; 396(2):375-83. PubMed ID: 19944704
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of Lys335 in the metastability and function of inhibitory serpins.
    Im H; Yu MH
    Protein Sci; 2000 May; 9(5):934-41. PubMed ID: 10850803
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alpha 1-antitrypsin polymerisation can occur by both loop A and C sheet mechanisms.
    Bottomley SP; Hopkins PC; Whisstock JC
    Biochem Biophys Res Commun; 1998 Oct; 251(1):1-5. PubMed ID: 9790897
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bypassing the kinetic trap of serpin protein folding by loop extension.
    Im H; Ahn HY; Yu MH
    Protein Sci; 2000 Aug; 9(8):1497-502. PubMed ID: 10975571
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Probing the equilibrium denaturation of the serpin alpha(1)-antitrypsin with single tryptophan mutants; evidence for structure in the urea unfolded state.
    Tew DJ; Bottomley SP
    J Mol Biol; 2001 Nov; 313(5):1161-9. PubMed ID: 11700071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Osmolyte mixtures have different effects than individual osmolytes on protein folding and functional activity.
    Warepam M; Singh LR
    Arch Biochem Biophys; 2015 May; 573():77-83. PubMed ID: 25817170
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin.
    Whisstock JC; Skinner R; Carrell RW; Lesk AM
    J Mol Biol; 2000 Feb; 296(2):685-99. PubMed ID: 10669617
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Engineering thermostability in serine protease inhibitors.
    Im H; Ryu MJ; Yu MH
    Protein Eng Des Sel; 2004 Apr; 17(4):325-31. PubMed ID: 15126675
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Viscous drag as the source of active site perturbation during protease translocation: insights into how inhibitory processes are controlled by serpin metastability.
    Shin JS; Yu MH
    J Mol Biol; 2006 Jun; 359(2):378-89. PubMed ID: 16626735
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Probing the local conformational change of alpha1-antitrypsin.
    Baek JH; Im H; Kang UB; Seong KM; Lee C; Kim J; Yu MH
    Protein Sci; 2007 Sep; 16(9):1842-50. PubMed ID: 17660256
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin.
    Whisstock JC; Skinner R; Carrell RW; Lesk AM
    J Mol Biol; 2000 Jan; 295(3):651-65. PubMed ID: 10623554
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of the connectivity of secondary structure segments in the folding of alpha(1)-antitrypsin.
    Lee C; Seo EJ; Yu MH
    Biochem Biophys Res Commun; 2001 Sep; 287(3):636-41. PubMed ID: 11563842
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA induces folding in alpha-synuclein: understanding the mechanism using chaperone property of osmolytes.
    Hegde ML; Rao KS
    Arch Biochem Biophys; 2007 Aug; 464(1):57-69. PubMed ID: 17537399
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Serpin polymerization and its role in disease--the molecular basis of alpha1-antitrypsin deficiency.
    Knaupp AS; Bottomley SP
    IUBMB Life; 2009 Jan; 61(1):1-5. PubMed ID: 18785256
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.
    Crowther DC; Belorgey D; Miranda E; Kinghorn KJ; Sharp LK; Lomas DA
    Eur J Hum Genet; 2004 Mar; 12(3):167-72. PubMed ID: 14694355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization and suppression of dysfunctional human alpha1-antitrypsin variants.
    Kim MJ; Jung CH; Im H
    Biochem Biophys Res Commun; 2006 Apr; 343(1):295-302. PubMed ID: 16540089
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.