BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 11768769)

  • 1. Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE).
    Kong AN; Owuor E; Yu R; Hebbar V; Chen C; Hu R; Mandlekar S
    Drug Metab Rev; 2001; 33(3-4):255-71. PubMed ID: 11768769
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential activation of MAPK and ICE/Ced-3 protease in chemical-induced apoptosis. The role of oxidative stress in the regulation of mitogen-activated protein kinases (MAPKs) leading to gene expression and survival or activation of caspases leading to apoptosis.
    Kong AN; Yu R; Lei W; Mandlekar S; Tan TH; Ucker DS
    Restor Neurol Neurosci; 1998 Jun; 12(2-3):63-70. PubMed ID: 12671299
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes.
    Rushmore TH; Kong AN
    Curr Drug Metab; 2002 Oct; 3(5):481-90. PubMed ID: 12369894
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of phase I, II and III drug metabolism/transport by xenobiotics.
    Xu C; Li CY; Kong AN
    Arch Pharm Res; 2005 Mar; 28(3):249-68. PubMed ID: 15832810
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. The role of oxidative stress in the activation of mitogen-activated protein kinases by phenolic antioxidants.
    Yu R; Tan TH; Kong AN
    J Biol Chem; 1997 Nov; 272(46):28962-70. PubMed ID: 9360968
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Signal transduction events elicited by cancer prevention compounds.
    Kong AN; Yu R; Hebbar V; Chen C; Owuor E; Hu R; Ee R; Mandlekar S
    Mutat Res; 2001 Sep; 480-481():231-41. PubMed ID: 11506817
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl isothiocyanate (PEITC).
    Keum YS; Owuor ED; Kim BR; Hu R; Kong AN
    Pharm Res; 2003 Sep; 20(9):1351-6. PubMed ID: 14567627
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death.
    Chen C; Yu R; Owuor ED; Kong AN
    Arch Pharm Res; 2000 Dec; 23(6):605-12. PubMed ID: 11156183
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antioxidants and oxidants regulated signal transduction pathways.
    Owuor ED; Kong AN
    Biochem Pharmacol; 2002 Sep; 64(5-6):765-70. PubMed ID: 12213568
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo pharmacokinetics, activation of MAPK signaling and induction of phase II/III drug metabolizing enzymes/transporters by cancer chemopreventive compound BHA in the mice.
    Hu R; Shen G; Yerramilli UR; Lin W; Xu C; Nair S; Kong AN
    Arch Pharm Res; 2006 Oct; 29(10):911-20. PubMed ID: 17121188
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals.
    Yu R; Lei W; Mandlekar S; Weber MJ; Der CJ; Wu J; Kong AN
    J Biol Chem; 1999 Sep; 274(39):27545-52. PubMed ID: 10488090
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2.
    Xu C; Yuan X; Pan Z; Shen G; Kim JH; Yu S; Khor TO; Li W; Ma J; Kong AN
    Mol Cancer Ther; 2006 Aug; 5(8):1918-26. PubMed ID: 16928811
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of heme oxygenase-1 (HO-1) and NAD[P]H: quinone oxidoreductase 1 (NQO1) by a phenolic antioxidant, butylated hydroxyanisole (BHA) and its metabolite, tert-butylhydroquinone (tBHQ) in primary-cultured human and rat hepatocytes.
    Keum YS; Han YH; Liew C; Kim JH; Xu C; Yuan X; Shakarjian MP; Chong S; Kong AN
    Pharm Res; 2006 Nov; 23(11):2586-94. PubMed ID: 17048120
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Signal transduction events elicited by natural products: role of MAPK and caspase pathways in homeostatic response and induction of apoptosis.
    Kong AN; Yu R; Chen C; Mandlekar S; Primiano T
    Arch Pharm Res; 2000 Feb; 23(1):1-16. PubMed ID: 10728649
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Butylated hydroxyanisole regulates ARE-mediated gene expression via Nrf2 coupled with ERK and JNK signaling pathway in HepG2 cells.
    Yuan X; Xu C; Pan Z; Keum YS; Kim JH; Shen G; Yu S; Oo KT; Ma J; Kong AN
    Mol Carcinog; 2006 Nov; 45(11):841-50. PubMed ID: 16739127
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of mitogen-activated protein kinases by green tea polyphenols: potential signaling pathways in the regulation of antioxidant-responsive element-mediated phase II enzyme gene expression.
    Yu R; Jiao JJ; Duh JL; Gudehithlu K; Tan TH; Kong AN
    Carcinogenesis; 1997 Feb; 18(2):451-6. PubMed ID: 9054642
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis.
    Saeki K; Kobayashi N; Inazawa Y; Zhang H; Nishitoh H; Ichijo H; Saeki K; Isemura M; Yuo A
    Biochem J; 2002 Dec; 368(Pt 3):705-20. PubMed ID: 12206715
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens.
    Yu R; Mandlekar S; Lei W; Fahl WE; Tan TH; Kong AN
    J Biol Chem; 2000 Jan; 275(4):2322-7. PubMed ID: 10644681
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1.
    Yu R; Jiao JJ; Duh JL; Tan TH; Kong AN
    Cancer Res; 1996 Jul; 56(13):2954-9. PubMed ID: 8674048
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dietary chemopreventive compounds and ARE/EpRE signaling.
    Chen C; Kong AN
    Free Radic Biol Med; 2004 Jun; 36(12):1505-16. PubMed ID: 15182853
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.