BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 11778052)

  • 1. Tumstatin, an endothelial cell-specific inhibitor of protein synthesis.
    Maeshima Y; Sudhakar A; Lively JC; Ueki K; Kharbanda S; Kahn CR; Sonenberg N; Hynes RO; Kalluri R
    Science; 2002 Jan; 295(5552):140-3. PubMed ID: 11778052
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins.
    Sudhakar A; Sugimoto H; Yang C; Lively J; Zeisberg M; Kalluri R
    Proc Natl Acad Sci U S A; 2003 Apr; 100(8):4766-71. PubMed ID: 12682293
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Vitronectin-αvβ3 integrin engagement directs hypoxia-resistant mTOR activity and sustained protein synthesis linked to invasion by breast cancer cells.
    Pola C; Formenti SC; Schneider RJ
    Cancer Res; 2013 Jul; 73(14):4571-8. PubMed ID: 23722547
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation.
    Horton LE; Bushell M; Barth-Baus D; Tilleray VJ; Clemens MJ; Hensold JO
    Oncogene; 2002 Aug; 21(34):5325-34. PubMed ID: 12149653
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway.
    Nathan CO; Amirghahari N; Abreo F; Rong X; Caldito G; Jones ML; Zhou H; Smith M; Kimberly D; Glass J
    Clin Cancer Res; 2004 Sep; 10(17):5820-7. PubMed ID: 15355912
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The PTEN/Akt pathway dictates the direct alphaVbeta3-dependent growth-inhibitory action of an active fragment of tumstatin in glioma cells in vitro and in vivo.
    Kawaguchi T; Yamashita Y; Kanamori M; Endersby R; Bankiewicz KS; Baker SJ; Bergers G; Pieper RO
    Cancer Res; 2006 Dec; 66(23):11331-40. PubMed ID: 17145879
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A; Usui I; Haruta T; Kawahara J; Uno T; Iwata M; Kobayashi M
    Mol Cell Biol; 2001 Aug; 21(15):5050-62. PubMed ID: 11438661
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Angiogenic role of adrenomedullin through activation of Akt, mitogen-activated protein kinase, and focal adhesion kinase in endothelial cells.
    Kim W; Moon SO; Sung MJ; Kim SH; Lee S; So JN; Park SK
    FASEB J; 2003 Oct; 17(13):1937-9. PubMed ID: 12897063
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of mammalian target of rapamycin signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma.
    Peponi E; Drakos E; Reyes G; Leventaki V; Rassidakis GZ; Medeiros LJ
    Am J Pathol; 2006 Dec; 169(6):2171-80. PubMed ID: 17148679
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers.
    Zhou X; Tan M; Stone Hawthorne V; Klos KS; Lan KH; Yang Y; Yang W; Smith TL; Shi D; Yu D
    Clin Cancer Res; 2004 Oct; 10(20):6779-88. PubMed ID: 15501954
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anti-HLA class I antibody-mediated activation of the PI3K/Akt signaling pathway and induction of Bcl-2 and Bcl-xL expression in endothelial cells.
    Jin YP; Fishbein MC; Said JW; Jindra PT; Rajalingam R; Rozengurt E; Reed EF
    Hum Immunol; 2004 Apr; 65(4):291-302. PubMed ID: 15120184
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of protein synthesis by IGF-I in proximal tubular epithelial cells.
    Senthil D; Choudhury GG; Abboud HE; Sonenberg N; Kasinath BS
    Am J Physiol Renal Physiol; 2002 Dec; 283(6):F1226-36. PubMed ID: 12388420
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.
    Wang X; Yue P; Chan CB; Ye K; Ueda T; Watanabe-Fukunaga R; Fukunaga R; Fu H; Khuri FR; Sun SY
    Mol Cell Biol; 2007 Nov; 27(21):7405-13. PubMed ID: 17724079
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells.
    Bhandari BK; Feliers D; Duraisamy S; Stewart JL; Gingras AC; Abboud HE; Choudhury GG; Sonenberg N; Kasinath BS
    Kidney Int; 2001 Mar; 59(3):866-75. PubMed ID: 11231341
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.
    Coutant A; Rescan C; Gilot D; Loyer P; Guguen-Guillouzo C; Baffet G
    Hepatology; 2002 Nov; 36(5):1079-88. PubMed ID: 12395317
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Puromycin insensitive leucyl-specific aminopeptidase (PILSAP) is involved in the activation of endothelial integrins.
    Akada T; Yamazaki T; Miyashita H; Niizeki O; Abe M; Sato A; Satomi S; Sato Y
    J Cell Physiol; 2002 Nov; 193(2):253-62. PubMed ID: 12385003
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of protein synthesis in apoptosis: differential requirements by the tumor necrosis factor alpha family and a DNA-damaging agent for caspases and the double-stranded RNA-dependent protein kinase.
    Jeffrey IW; Bushell M; Tilleray VJ; Morley S; Clemens MJ
    Cancer Res; 2002 Apr; 62(8):2272-80. PubMed ID: 11956083
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M; Kasprzycka M; Liu X; El-Salem M; Halasa K; Raghunath PN; Bucki R; Wlodarski P; Wasik MA
    Oncogene; 2007 Aug; 26(38):5606-14. PubMed ID: 17353907
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ErbB2 promotes Src synthesis and stability: novel mechanisms of Src activation that confer breast cancer metastasis.
    Tan M; Li P; Klos KS; Lu J; Lan KH; Nagata Y; Fang D; Jing T; Yu D
    Cancer Res; 2005 Mar; 65(5):1858-67. PubMed ID: 15753384
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Raptor-rictor axis in TGFbeta-induced protein synthesis.
    Das F; Ghosh-Choudhury N; Mahimainathan L; Venkatesan B; Feliers D; Riley DJ; Kasinath BS; Choudhury GG
    Cell Signal; 2008 Feb; 20(2):409-23. PubMed ID: 18068336
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.