These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 11779863)

  • 1. Transactivation of ErbB2 and ErbB3 by tumor necrosis factor-alpha and anisomycin leads to impaired insulin signaling through serine/threonine phosphorylation of IRS proteins.
    Hemi R; Paz K; Wertheim N; Karasik A; Zick Y; Kanety H
    J Biol Chem; 2002 Mar; 277(11):8961-9. PubMed ID: 11779863
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p38 mitogen-activated protein kinase-dependent transactivation of ErbB receptor family: a novel common mechanism for stress-induced IRS-1 serine phosphorylation and insulin resistance.
    Hemi R; Yochananov Y; Barhod E; Kasher-Meron M; Karasik A; Tirosh A; Kanety H
    Diabetes; 2011 Apr; 60(4):1134-45. PubMed ID: 21386087
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1.
    Kanety H; Feinstein R; Papa MZ; Hemi R; Karasik A
    J Biol Chem; 1995 Oct; 270(40):23780-4. PubMed ID: 7559552
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tumor necrosis factor alpha-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes.
    Engelman JA; Berg AH; Lewis RY; Lisanti MP; Scherer PE
    Mol Endocrinol; 2000 Oct; 14(10):1557-69. PubMed ID: 11043572
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON; Akca H; Mayo LD; Gustin JA; Maehama T; Dixon JE; Donner DB
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4640-5. PubMed ID: 11287630
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chronic tumor necrosis factor-alpha treatment causes insulin resistance via insulin receptor substrate-1 serine phosphorylation and suppressor of cytokine signaling-3 induction in 3T3-L1 adipocytes.
    Ishizuka K; Usui I; Kanatani Y; Bukhari A; He J; Fujisaka S; Yamazaki Y; Suzuki H; Hiratani K; Ishiki M; Iwata M; Urakaze M; Haruta T; Kobayashi M
    Endocrinology; 2007 Jun; 148(6):2994-3003. PubMed ID: 17379643
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Platelet-derived growth factor inhibits insulin stimulation of insulin receptor substrate-1-associated phosphatidylinositol 3-kinase in 3T3-L1 adipocytes without affecting glucose transport.
    Staubs PA; Nelson JG; Reichart DR; Olefsky JM
    J Biol Chem; 1998 Sep; 273(39):25139-47. PubMed ID: 9737973
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphoinositide 3-kinase-mediated reduction of insulin receptor substrate-1/2 protein expression via different mechanisms contributes to the insulin-induced desensitization of its signaling pathways in L6 muscle cells.
    Pirola L; Bonnafous S; Johnston AM; Chaussade C; Portis F; Van Obberghen E
    J Biol Chem; 2003 May; 278(18):15641-51. PubMed ID: 12594228
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner.
    de Alvaro C; Teruel T; Hernandez R; Lorenzo M
    J Biol Chem; 2004 Apr; 279(17):17070-8. PubMed ID: 14764603
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways.
    Rui L; Aguirre V; Kim JK; Shulman GI; Lee A; Corbould A; Dunaif A; White MF
    J Clin Invest; 2001 Jan; 107(2):181-9. PubMed ID: 11160134
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins.
    Liu YF; Paz K; Herschkovitz A; Alt A; Tennenbaum T; Sampson SR; Ohba M; Kuroki T; LeRoith D; Zick Y
    J Biol Chem; 2001 Apr; 276(17):14459-65. PubMed ID: 11278339
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.
    Hançer NJ; Qiu W; Cherella C; Li Y; Copps KD; White MF
    J Biol Chem; 2014 May; 289(18):12467-84. PubMed ID: 24652289
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307).
    Aguirre V; Uchida T; Yenush L; Davis R; White MF
    J Biol Chem; 2000 Mar; 275(12):9047-54. PubMed ID: 10722755
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation.
    Pederson TM; Kramer DL; Rondinone CM
    Diabetes; 2001 Jan; 50(1):24-31. PubMed ID: 11147790
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PKCdelta and mTOR interact to regulate stress and IGF-I induced IRS-1 Ser312 phosphorylation in breast cancer cells.
    Mingo-Sion AM; Ferguson HA; Koller E; Reyland ME; Van Den Berg CL
    Breast Cancer Res Treat; 2005 Jun; 91(3):259-69. PubMed ID: 15952059
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin resistance.
    Kim JA; Yeh DC; Ver M; Li Y; Carranza A; Conrads TP; Veenstra TD; Harrington MA; Quon MJ
    J Biol Chem; 2005 Jun; 280(24):23173-83. PubMed ID: 15849359
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling.
    Tanti JF; Grémeaux T; van Obberghen E; Le Marchand-Brustel Y
    J Biol Chem; 1994 Feb; 269(8):6051-7. PubMed ID: 8119950
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphatidylinositol 3'-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase.
    Cengel KA; Kason RE; Freund GG
    Biochem J; 1998 Oct; 335 ( Pt 2)(Pt 2):397-404. PubMed ID: 9761740
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TNF-alpha impairs insulin signaling and insulin stimulation of glucose uptake in C2C12 muscle cells.
    del Aguila LF; Claffey KP; Kirwan JP
    Am J Physiol; 1999 May; 276(5):E849-55. PubMed ID: 10329978
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential regulation of insulin receptor substrate-2 and mitogen-activated protein kinase tyrosine phosphorylation by phosphatidylinositol 3-kinase inhibitors in SH-SY5Y human neuroblastoma cells.
    Kim B; Leventhal PS; White MF; Feldman EL
    Endocrinology; 1998 Dec; 139(12):4881-9. PubMed ID: 9832424
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.