BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 11790725)

  • 1. Nuclear degradation of p53 occurs during down-regulation of the p53 response after DNA damage.
    Shirangi TR; Zaika A; Moll UM
    FASEB J; 2002 Mar; 16(3):420-2. PubMed ID: 11790725
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nuclear and cytoplasmic degradation of endogenous p53 and HDM2 occurs during down-regulation of the p53 response after multiple types of DNA damage.
    Joseph TW; Zaika A; Moll UM
    FASEB J; 2003 Sep; 17(12):1622-30. PubMed ID: 12958168
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analysis of nuclear and cytoplasmic degradation of p53 in cells after stress.
    Joseph TW; Moll UM
    Methods Mol Biol; 2003; 234():211-7. PubMed ID: 12824534
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53.
    Xirodimas DP; Stephen CW; Lane DP
    Exp Cell Res; 2001 Oct; 270(1):66-77. PubMed ID: 11597128
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.
    Roth J; Dobbelstein M; Freedman DA; Shenk T; Levine AJ
    EMBO J; 1998 Jan; 17(2):554-64. PubMed ID: 9430646
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53.
    Tao W; Levine AJ
    Proc Natl Acad Sci U S A; 1999 Mar; 96(6):3077-80. PubMed ID: 10077639
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MDM2 can promote the ubiquitination, nuclear export, and degradation of p53 in the absence of direct binding.
    Inoue T; Geyer RK; Howard D; Yu ZK; Maki CG
    J Biol Chem; 2001 Nov; 276(48):45255-60. PubMed ID: 11572869
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6.
    Freedman DA; Levine AJ
    Mol Cell Biol; 1998 Dec; 18(12):7288-93. PubMed ID: 9819415
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nuclear exclusion of p53 in a subset of tumors requires MDM2 function.
    Lu W; Pochampally R; Chen L; Traidej M; Wang Y; Chen J
    Oncogene; 2000 Jan; 19(2):232-40. PubMed ID: 10645001
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.
    Boyd SD; Tsai KY; Jacks T
    Nat Cell Biol; 2000 Sep; 2(9):563-8. PubMed ID: 10980695
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation.
    Migliorini D; Danovi D; Colombo E; Carbone R; Pelicci PG; Marine JC
    J Biol Chem; 2002 Mar; 277(9):7318-23. PubMed ID: 11744695
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of nuclear export in human papillomavirus type 18 E6-mediated ubiquitination and degradation of p53.
    Stewart D; Ghosh A; Matlashewski G
    J Virol; 2005 Jul; 79(14):8773-83. PubMed ID: 15994771
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MDM2-dependent ubiquitination of nuclear and cytoplasmic P53.
    Yu ZK; Geyer RK; Maki CG
    Oncogene; 2000 Nov; 19(51):5892-7. PubMed ID: 11127820
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Overexpression of Mdm2 and MdmX fusion proteins alters p53 mediated transactivation, ubiquitination, and degradation.
    Ghosh M; Huang K; Berberich SJ
    Biochemistry; 2003 Mar; 42(8):2291-9. PubMed ID: 12600196
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation.
    Zhang Y; Xiong Y
    Science; 2001 Jun; 292(5523):1910-5. PubMed ID: 11397945
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.
    Li M; Brooks CL; Wu-Baer F; Chen D; Baer R; Gu W
    Science; 2003 Dec; 302(5652):1972-5. PubMed ID: 14671306
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The contribution of the acidic domain of MDM2 to p53 and MDM2 stability.
    Argentini M; Barboule N; Wasylyk B
    Oncogene; 2001 Mar; 20(11):1267-75. PubMed ID: 11313871
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation.
    Stommel JM; Wahl GM
    EMBO J; 2004 Apr; 23(7):1547-56. PubMed ID: 15029243
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs.
    LaĆ­n S; Midgley C; Sparks A; Lane EB; Lane DP
    Exp Cell Res; 1999 May; 248(2):457-72. PubMed ID: 10222137
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The MDM2 RING-finger domain is required to promote p53 nuclear export.
    Geyer RK; Yu ZK; Maki CG
    Nat Cell Biol; 2000 Sep; 2(9):569-73. PubMed ID: 10980696
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.