BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 11793442)

  • 1. Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer.
    Nyström-Lahti M; Perrera C; Räschle M; Panyushkina-Seiler E; Marra G; Curci A; Quaresima B; Costanzo F; D'Urso M; Venuta S; Jiricny J
    Genes Chromosomes Cancer; 2002 Feb; 33(2):160-7. PubMed ID: 11793442
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic and epigenetic modification of MLH1.
    Perucho M
    Am J Pathol; 2000 Sep; 157(3):1052-3. PubMed ID: 10980144
    [No Abstract]   [Full Text] [Related]  

  • 3. A conserved motif in the disordered linker of human MLH1 is vital for DNA mismatch repair and its function is diminished by a cancer family mutation.
    Wolf K; Kosinski J; Gibson TJ; Wesch N; Dötsch V; Genuardi M; Cordisco EL; Zeuzem S; Brieger A; Plotz G
    Nucleic Acids Res; 2023 Jul; 51(12):6307-6320. PubMed ID: 37224528
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome.
    Abildgaard AB; Stein A; Nielsen SV; Schultz-Knudsen K; Papaleo E; Shrikhande A; Hoffmann ER; Bernstein I; Gerdes AM; Takahashi M; Ishioka C; Lindorff-Larsen K; Hartmann-Petersen R
    Elife; 2019 Nov; 8():. PubMed ID: 31697235
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Involvement of p53 mutation and mismatch repair proteins dysregulation in NNK-induced malignant transformation of human bronchial epithelial cells.
    Shen Y; Zhang S; Huang X; Chen K; Shen J; Wang Z
    Biomed Res Int; 2014; 2014():920275. PubMed ID: 25215298
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multiple mutations and frameshifts are the hallmark of defective hPMS2 in pZ189-transfected human tumor cells.
    Ceccotti S; Ciotta C; Fronza G; Dogliotti E; Bignami M
    Nucleic Acids Res; 2000 Jul; 28(13):2577-84. PubMed ID: 10871409
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Classification of MLH1 Missense VUS Using Protein Structure-Based Deep Learning-Ramachandran Plot-Molecular Dynamics Simulations Method.
    Tam B; Qin Z; Zhao B; Sinha S; Lei CL; Wang SM
    Int J Mol Sci; 2024 Jan; 25(2):. PubMed ID: 38255924
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations affecting a putative MutLalpha endonuclease motif impact multiple mismatch repair functions.
    Erdeniz N; Nguyen M; Deschênes SM; Liskay RM
    DNA Repair (Amst); 2007 Oct; 6(10):1463-70. PubMed ID: 17567544
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a Catalytic Lysine Residue Conserved Among GHKL ATPases: MutL, GyrB, and MORC.
    Fukui K; Fujii Y; Yano T
    J Mol Biol; 2024 Apr; 436(10):168575. PubMed ID: 38641238
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Urothelial carcinoma in a man with hereditary nonpolyposis colon cancer.
    Lenz DL; Harpster LE
    Rev Urol; 2003; 5(1):49-53. PubMed ID: 16985618
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional significance and clinical phenotype of nontruncating mismatch repair variants of MLH1.
    Raevaara TE; Korhonen MK; Lohi H; Hampel H; Lynch E; Lönnqvist KE; Holinski-Feder E; Sutter C; McKinnon W; Duraisamy S; Gerdes AM; Peltomäki P; Kohonen-Ccorish M; Mangold E; Macrae F; Greenblatt M; de la Chapelle A; Nyström M
    Gastroenterology; 2005 Aug; 129(2):537-49. PubMed ID: 16083711
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional analysis of HNPCC-related missense mutations in MSH2.
    Lützen A; de Wind N; Georgijevic D; Nielsen FC; Rasmussen LJ
    Mutat Res; 2008 Oct; 645(1-2):44-55. PubMed ID: 18822302
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional analysis of human MLH1 variants using yeast and in vitro mismatch repair assays.
    Takahashi M; Shimodaira H; Andreutti-Zaugg C; Iggo R; Kolodner RD; Ishioka C
    Cancer Res; 2007 May; 67(10):4595-604. PubMed ID: 17510385
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional characterization of MLH1 missense variants identified in Lynch syndrome patients.
    Andersen SD; Liberti SE; Lützen A; Drost M; Bernstein I; Nilbert M; Dominguez M; Nyström M; Hansen TV; Christoffersen JW; Jäger AC; de Wind N; Nielsen FC; Tørring PM; Rasmussen LJ
    Hum Mutat; 2012 Dec; 33(12):1647-55. PubMed ID: 22753075
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanisms of pathogenicity in human MSH2 missense mutants.
    Ollila S; Dermadi Bebek D; Jiricny J; Nyström M
    Hum Mutat; 2008 Nov; 29(11):1355-63. PubMed ID: 18951462
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae.
    Shimodaira H; Filosi N; Shibata H; Suzuki T; Radice P; Kanamaru R; Friend SH; Kolodner RD; Ishioka C
    Nat Genet; 1998 Aug; 19(4):384-9. PubMed ID: 9697702
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Assessing how reduced expression levels of the mismatch repair genes MLH1, MSH2, and MSH6 affect repair efficiency.
    Kansikas M; Kasela M; Kantelinen J; Nyström M
    Hum Mutat; 2014 Sep; 35(9):1123-7. PubMed ID: 24924810
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Verification of the three-step model in assessing the pathogenicity of mismatch repair gene variants.
    Kansikas M; Kariola R; Nyström M
    Hum Mutat; 2011 Jan; 32(1):107-15. PubMed ID: 21120944
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Analysis of mismatch repair gene mutations in Turkish HNPCC patients.
    Tunca B; Pedroni M; Cecener G; Egeli U; Borsi E; Zorluoglu A; Di Gregorio C; Yilmazlar T; Yerci O; de Leon MP
    Fam Cancer; 2010 Sep; 9(3):365-76. PubMed ID: 20373145
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional analysis of MSH6 mutations linked to kindreds with putative hereditary non-polyposis colorectal cancer syndrome.
    Kariola R; Raevaara TE; Lönnqvist KE; Nyström-Lahti M
    Hum Mol Genet; 2002 May; 11(11):1303-10. PubMed ID: 12019211
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.